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PROTEINS

PROTEINS. The final product of the DNA blueprint. Hemoglobin. Why are proteins important?. “When the body has something it needs to do, it is a protein that does it” http://www.rothamsted.ac.uk/notebook/courses/guide/prot.htm. Antibodies – fight disease. Why are proteins important?.

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PROTEINS

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  1. PROTEINS The final product of the DNA blueprint Hemoglobin

  2. Why are proteins important? “When the body has something it needs to do, it is a protein that does it” http://www.rothamsted.ac.uk/notebook/courses/guide/prot.htm Antibodies – fight disease

  3. Why are proteins important? “When the body has something it needs to do, it is a protein that does it” http://www.rothamsted.ac.uk/notebook/courses/guide/prot.htm Receptors – part of cell membrane, recognize other proteins and inform the cell (“The Door Bell”)

  4. Why are proteins important? “When the body has something it needs to do, it is a protein that does it” http://www.rothamsted.ac.uk/notebook/courses/guide/prot.htm Enzyme that digests insulin Enzymes – assemble or digest

  5. Why are proteins important? “When the body has something it needs to do, it is a protein that does it” http://www.rothamsted.ac.uk/notebook/courses/guide/prot.htm Neurotransmitters Neurotransmitters and hormones – trigger the receptor (“finger on the doorbell”)

  6. Why are proteins important? Channels and pores – holes in the cell membrane

  7. What determines the role or function of a protein? Shape – click for examples

  8. Amino Group Acid Group What determines the shape of a protein? Amino acids are building blocks of proteins

  9. What determines the shape of a protein? 20 different amino acids each with their own size, shape, and charge

  10. What determines the shape of a protein? Amino acids are connected by peptide bonds

  11. Four levels of structure Primary Structure – Sequence of amino acids.

  12. Four levels of structure Secondary Structure – some chains form an alpha helix (coil) or a beta sheet (accordion).

  13. Four levels of structure Tertiary Structure – How all of the helices and sheets fold together.

  14. Four levels of structure Quaternary Structure – some proteins are made of more than one subunit.

  15. What is denaturing? Denaturing – Losing shape. Proteins that have lost their shape can’t function correctly. What can cause a protein to denature? VIDEO

  16. How does the body know how to make proteins? • DNA sequence. • If nucleotide order is changed: • - sequence of amino acids is changed. • - Shape of protein is different. • - Protein loses function. Cystic Fibrosis Video – “Cracking the Code” Chapter 9 – it’s in the DVD drive ;)

  17. Genetic Testing Video CLICK HERE - http://topics.nytimes.com/top/news/national/series/dnaage/index.html - WATCH “When a DNA Test Shows a Lethal Fate”

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