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DNA

DNA. BIBC 100. Alphabet = language L,I,F,E LIFE DNA = DNA code A, T, C, G CAC =Histidine CAG =Glutamine GGG =Glycine Protein = Protein code 20 a.a. L, I, F, E N C not CN. Sequence = Information. LIVE EVIL. DNA. A DNA chain has polarity

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DNA

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  1. DNA BIBC 100

  2. Alphabet = language L,I,F,E LIFE DNA = DNA code A, T, C, G CAC=Histidine CAG=Glutamine GGG=Glycine Protein = Protein code 20 a.a. L, I, F, E NC not CN Sequence = Information LIVEEVIL

  3. DNA • A DNA chain has polarity • Just as for proteins we have N C, For DNA the base sequence is 5’ 3’ Both proteins and DNA are polymers with sequence specificity and directionality Protein: Polypeptide DNA: Polynucleotide Amino-end Carboxy-end 5’ OH unlinked 3’ OH unlinked

  4. DNA • Four kinds of bases joined to a sugar-phosphate backbone • Long molecule • Packed – right handed helical staircase (double helix) • Rails: antiparallel sugar-phosphate chains • Steps: Purine-Pyrimidine H-bonded base pairs • Polarity: sequence 5’3’ direction ACG is different to GCA

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