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Nicardipine

Nicardipine. Antihypertensive Drugs. Diuretics Beta blockers ACE-inhibitors Angiotensin II receptor blockers (ARB) Ca antagonist Verapamil Diltiazem Dihydropiridine (DHP)  nifedipine, nicardipine. Katzung BG. Basic and clinical pharmacology. 10 th ed. USA: McGraw-Hill; 2006.

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Nicardipine

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  1. Nicardipine

  2. Antihypertensive Drugs • Diuretics • Beta blockers • ACE-inhibitors • Angiotensin II receptor blockers (ARB) • Ca antagonist • Verapamil • Diltiazem • Dihydropiridine (DHP)  nifedipine, nicardipine Katzung BG. Basic and clinical pharmacology. 10th ed. USA: McGraw-Hill; 2006.

  3. Nicardipine • Mechanism of action: inhibitcalcium influx into arterial smooth muscle cells. • IV preparation  100% bioavailability • > 90% hepatic metabolism • Minimum renal excretion  safe for renal insufficiency • Indication: hypertensive crisis • Side effect: hypotension Katzung BG. Basic and clinical pharmacology. 10th ed. USA: McGraw-Hill; 2006.

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