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Study Design Grading Systems

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Study Design Grading Systems

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    1. Study Design Grading Systems

    2. Overview of Study Designs

    3. Well Designed Reports Randomization Concealed allocation Double-blinding Complete patient follow-up Intention-to-treat analysis

    4. Grade the Evidence McMaster Grading System Grade 1: Large, well-designed randomized controlled clinical trials Grade 2: Small, or not-so-well-designed controlled clinical trials Grade 3: Non-randomized prospective cohort studies Grade 4: Non-randomized historical cohort studies, case-control studies Grade 5: Case series Grade 6: Expert opinion

    5. Grade the Evidence AHRQ Grading System Grade IA: Meta-analysis of RCTs Grade IB: At least one RCT Grade II: At least one well-designed controlled study without randomization Grade III: Well-designed, non-experimental, descriptive studies; e.g., comparison study, correlation study, or case-control study Grade IV: Experiences of expert committees or experts; case reports

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