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London (South) Comprehensive Local Research Network

Learn about the NIHR and the CLRN funding for dementia research. Explore the benefits and eligibility for accessing NHS service support and the NIHR Coordinated System for gaining NHS permission. Discover the funding flow and open funding calls.

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London (South) Comprehensive Local Research Network

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  1. London (South)Comprehensive Local Research Network Clare Gillott Lead RM&G Manager

  2. Agenda • Background to NIHR and the CLRN • CLRN funding • NIHR Coordinated System for gaining NHS Permission (NIHR CSP) • Dementia research

  3. 6 TCRNs Stroke, Cancer, Diabetes, Mental Health, PCRN Medicines for Children, CCRN Dementias and neurodegenerative diseases 25 Comprehensive Clinical Research NIHR Clinical Networks Research Network Coordinating Centre Overview of NIHR CRN

  4. Our Goals • To ensure all areas of healthcare can take part in clinical research • Remove barriers to research within the NHS • Streamline administrative procedures associated with regulation, governance, reporting and approvals • Strengthen research collaboration with industry

  5. NIHR Clinical Research Network Portfolio • Eligibility • Funded by peer reviewed open national competition or commercial • Of benefit to NHS • Advantages • Access to NHS Service Support • Access to set up support (CLRN, TCRN, PCRN) • Access to NIHR Coordinated System for gaining NHS permission (CSP)

  6. CLRN funding allocation • Clinical Research Coordinating Centre allocates funding to CLRNs based on uploaded accrual to the NIHR Portfolio • L(S) CLRN allocates funding to member Trusts based on accrual uploads (70%) and # Studies (30%) – This is currently being re-modelled for 2011/12

  7. NIHR CRN £258m L(S) CLRN £18m Institution costs • HR • Finance • Estates • Facilities Funding Flow 2010/11 Member Trusts 60% 10% 10% 20% Service Support Research Management & Governance Sessions for clinicians, nurses and other support staff • Routine service support • Key service Support • Imaging • Pharmacy • Research passport • CSP (R&D approval) • Costing • Study management

  8. Open funding calls: • CLRN Contingency funding available to support: • Salary costs for staff recruiting to CLRN portfolio studies which cannot be covered by any other sources (devolved CLRN funding via Trust R&D departments, research grants, Trust FSF allocations etc) • Existing NIHR faculty members who are “between grants” • Research-related time of NHS-employed administrative and secretarial staff that are supporting recruitment to CLRN portfolio studies

  9. Service support costs for studies that commence in year and cannot be funded by R&D departments • Unforeseen in year costs where recruitment would fail without additional support. More information and details on how to apply are on the London (South) CLRN website: http://www.crncc.nihr.ac.uk/about_us/ccrn/slondon/Funding

  10. Coordinated System for Gaining NHS Permission (NIHR CSP)

  11. NIHR CSP Benefits Consistency – consistent and comprehensive set of NHS research governance checks Speed – streamlining and rationalising processes to reduce NHS R&D approval times Predictability – a single system for processing and reviewing applications for NHS permission, centrally coordinated and supported through NIHR Comprehensive Local Research Networks

  12. CSP principles • All instructions and submissions through IRAS • Study wide activity: • CI makes study wide submission through IRAS • Lead CLRN completes global governance • Documents and governance made available to all sites taking part in the study • Local activity: • Local PI makes local submission through IRAS, includes; • Signed SSI form • Localised PIS and consent forms • Research team CVs • Local site completes local governance

  13. Global governance undertaken once for the whole study • Local governance undertaken at each site • Once global and local review complete site issues NHS Permission • Substantial amendments managed through the system – no need for PIs to submit to local R&D Offices • However it is still the sponsors responsibility to provide PI’s with documentation

  14. London (South) CLRN • CSP functionality devolved out to member trusts • Trust R&D Departments assume roles of Lead and Host CLRN contact • R&D Departments able to provide full advice on CSP and IRAS submission process • All documentation submitted to the R&D Department will be uploaded to CSP (including substantial amendments) • R&D Department responsible for undertaking governance checks within CSP and issuing NHS Permission

  15. Dementia research: • Identified as the only priority area by the Government for 2011/12 • In response to this the CLRN have: • Set up a Dementia Specialty group • Funded a dementia nurse to help with the set-up and delivery of Dementia studies If interested in being part of the Dementia Specialty Group please contact the CLRN for meeting details

  16. Any questions?

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