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University of Cincinnati

University of Cincinnati. Intellectual Property Office. UC Firsts. First oral polio vaccine – Albert Sabin First antihistamine, Benadryl – George Rieveschl First safe anti-knock gasoline First electric organ – Winston Koch First use of a YAG laser to remove brain tumor.

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University of Cincinnati

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  1. University of Cincinnati Intellectual Property Office

  2. UC Firsts • First oral polio vaccine – Albert Sabin • First antihistamine, Benadryl – George Rieveschl • First safe anti-knock gasoline • First electric organ – Winston Koch • First use of a YAG laser to remove brain tumor

  3. Mission of Intellectual Property Office • Main Mission - Technology Transfer • Assess new invention disclosures • Develop strategies for protecting University’s IP • Transfer University’s IP to industry for the public good and commercial gain (increase society’s wealth locally and nationally) • Promote entrepreneurship through faculty counseling and referral • Provide University presence within industrial and investment communities

  4. Technology Transfer Process • Process begins with the submission of an invention disclosure • Evaluation involves the investigation of many complex patent/legal, ownership and business related questions. • Esp pre-existing obligations to sponsor

  5. Ongoing Administrative Obligations • Bayh-Dole Compliance • Reporting • Election of Title • Patent Filing Decisions • Invention Utilization • Licensee Diligence • Progress reports • Milestone, royalty payments

  6. Skills Set • Complexity of University Technology Transfer demands sophisticated knowledge of many different fields • patent law • licensing & contract law • federal, state, and university polices & laws related to IP • in-depth understanding of market trends • capacity to understand new technical developments • We’re fortunate in our office to have a team with a highly complimentary skills set (PhD, JD, MBA)

  7. Intellectual Property Staff

  8. About Our Office • Approx 75 active licenses • 164 active patents • $6.5 million in license revenue in FY02 • Over 50% of US patents issued to us in the last 5 years have been licensed or optioned to industry • Top 1/3 of Technology Transfer Offices nationwide, top office in tri-state

  9. Invention Disclosures and Patents

  10. Licensing Income

  11. UC IP Helping to Advance Local Firms • Small Firms • KY Pharmaceutical firm • Considering license to slow-release diuretic technology and sponsoring research to develop the product. Also considering re-locating R&D from KY to Bio/Start • Local Medical Device firm • Considering license to early stroke diagnostic technology and also sponsoring research at UC to develop the medical device • Local Biosensor firm • Interested in acquiring a license to our biosensor technology and partnering with us on development environment monitoring equipment

  12. UC Helping Cont’d • Large Firms • P&G Pharmaceuticals • Collaborative research in area of obesity • Halliburtin • Oil drilling technology • GE • Aerospace technology

  13. Example Recent License Agreement • Inventors - Drs. Joseph Clark (UC) and Ton Degrauw (Children’s Hospital) and Rima Daouk (Avicena) • Licensee - Avicena (Biotech in Cambridge, MA) • Invention - Discovered that a mutations in gene that encodes creatine transport protein located on X chromosome (afflicts males) can cause mental retardation • Currently working on a cure • License complemented with sponsored research agreement designed to determine prevalence of this defect and to identify therapeutics

  14. Examples of Faculty Start-ups • Extreme Photonics (solid-state display) • Apologic (develops drugs for Apo-E related diseases, e.g., Alzheimer’s) • CardioEnergetics (mechanical devices for treating heart failure) • Cutanogen (skin substitutes) • Allergenics (oral vaccines) • Phase 2 Discovery (develops drugs for treating psychiatric and neurologic disorders) • Intracellular (cellular imaging instruments)

  15. "Extreme" Engineering Innovation Launches High-tech FirmAn idea born in the labs of Ohio Eminent Scholar Andrew Steckl led to the birth of Cincinnati's newest high-tech company -- Extreme Photonix. The company was started by Steckl, Gieringer Professor of Solid State Microelectronics in the electrical and computer engineering and computer science department. Research Corporation Technologies (RCT) of Tuscon, Ariz., recently announced it would support the company's research and development so prototype products can be made. Extreme Photonics

  16. Examples of Licensing Opportunities • Pharmacogenomics • Genetic test for asthma and congestive heart patients to help physician to determine best drug • Diagnostic • Blood test that can diagnosis any neurological disease (stroke, epilepsy, possibly even Alzheimer’s) • Medical Device • Ultrasonic “clot busting” device for treating stroke • Therapeutic • Patented Cystic Fibrosis drug

  17. Ultrasound Enhances tPA Thrombolysis

  18. Questions Richard Kordal, Ph.D., Director, IPO University of Cincinnati Mail Location 0829 Cincinnati, OH 45267-0829 Ph: (513) 556-4724 Fax: (513) 558-2296 Email: richard.kordal@uc.edu

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