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Table S2. Cell cycle mutants simulated by our model of DNA replication initiation.

Table S2. Cell cycle mutants simulated by our model of DNA replication initiation. * This is an estimate of the defect of cdc45-1 in initiating replication. It is likely that the phenotype is more severe in vivo .

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Table S2. Cell cycle mutants simulated by our model of DNA replication initiation.

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  1. Table S2. Cell cycle mutants simulated by our model of DNA replication initiation. • * This is an estimate of the defect of cdc45-1 in initiating replication. It is likely that the phenotype is more severe in vivo. • ** This is simulated using Cdc45 as a proxy for the complex that stabilizes CMG at origins. A three-fold increase in levels and association (overexpression) was simulated by the model based on Western blotting results from [3]. Table S3. Cell cycle mutants reported in Chen et al. [45], simulated by the combined model.

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