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Mobile elements existence in mycobacteriophages

Mobile elements existence in mycobacteriophages. Farah Dahman Bioinformatics 301. Background information. Evolution of mycobacteriophage (transposons) ( mosaicism ) Mobile Elements MPEME1 & MPME2. Method .

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Mobile elements existence in mycobacteriophages

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  1. Mobile elements existence in mycobacteriophages Farah DahmanBioinformatics 301

  2. Background information • Evolution of mycobacteriophage (transposons) (mosaicism) • Mobile Elements MPEME1 & MPME2

  3. Method • Phages studied: Cluster F (average length- 57,422bp)Fruit Loop, DotProduct, Bobi, Yoshi, Taj  

  4. METHOD CONTINUED • Run this method for each phage -compared sequence relations -repetitive sequence within each? -Mobile Element possibility

  5. How to know if mobile element found • Classified their phages to have mobile element in them • 5′-TTATC[a/t]GGGGT-3’MPEME1MPEME2 changes at positon 8 • If find in phages, find match “MycobacteriophagesBPs, Angel and Halo: comparative genomics reveals a novel class of ultra-small mobile genetic elements.”

  6. Conclusion • Results still being compared

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