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Pharmaceuticals Techno Development – Tatvachintan

It has been found out that inspite of all the time, energy and resources spent in research and development process for pharmaceutical drug development and discovery, no more than 1% of drugs in the discovery and development funnel reached the marketplace. The rates of failure are too high, and all too often drug candidates fail relatively late in development, having already consumed substantial time and resources. TatvaChintan provides pharmaceuticals raw materials that have proved to be a bane for pahrmaceutical companies.<br>

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Pharmaceuticals Techno Development – Tatvachintan

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  1. Technological Advancement Technological Advancement A Bellwether for Pharmaceutical Drug Development

  2. Introduction Introduction The drug development industry is entering a new technology era that is filled with both opportunities and challenges. Due to an increasing array of cost-reduction, efficiency objectives and safety drivers from the commercial, regulatory and patient sectors research organizations are embracing innovative technologies across the entire drug development continuum at a tremendous pace.

  3. Manufacturing Technology From discovery through clinical research, the integration, analysis and reporting of data to support biomarker and product development is one of the critical paths in the drug development process. Various forms of data exist to support the research process: Patient Consent ● Protocol Design ● Drug Safety ● Genome and Biomarker analysis ● Clinical Laboratory Results ● Sample Inventory ● Bioinformatics Data ●

  4. Molecular Modeling Molecular modeling encompasses all theoretical methods and computational techniques used to model or mimic the behavior of molecules. The simplest calculations can be performed by hand, but inevitably computers are required to perform molecular modeling of any reasonably sized system. Its common feature is the atomistic level description of the molecular systems & include treating atoms as the smallest individual unit or explicitly modeling electrons of each atom.

  5. Computational Chemistry Computational chemistry work in a property driven paradigm where scientists specify first the property of the molecule then the procedure for its determination. This allows them to quickly specify the properties for a virtual compound library and trigger automated calculations. It uses methods that are incorporated into efficient computer programs, to calculate the structures and properties of molecules and solids.

  6. Latest Trends – Research & development Liquid Chromatography -Mass Spectrometry The growth of the pharmaceutical industry is heavily dependent on its constant research into new products and the enhancement of those products already on the market. LC-MS is a sophisticated analytical chemistry technique that amalgamates the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Preparative LC-MS systems can be used for rapid mass-directed purification of specific substances from such mixtures that are important in basic research, and pharmaceutical, agro-chemical, food, and other industries.

  7. Schematic Diagram

  8. LC MS - Advantages Increased throughput. ● Avoids transfer of multiple small samples multiple times. ● Reduction of data processing costs for mass spectrometry. ● Advancement in sensitivity and ease of use ● Better analysis of proteins, peptides, and oligonucleotides ● Development of suitable software for identification of protein ●

  9. About Us!! We combine economic success, social responsibility and environmental protection. Through science and innovation, we support our customers in nearly every industry in meeting the current and future needs of society. We aim to strengthen its position as one of the world’s leading specialty chemical company & our products contribute to conserving resources and improving quality of life. Sustainability and innovation will be significant driving forces.

  10. Contact Us!! Address950 Taylor Avenue Suite 230A Grand Haven, MI 49417 USA Contact (616) 607-7073 (616) 402-4911 Email Address curt@tatvachintan.com Website www.tatvachintan.com

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