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Klinik und Poliklinik für Augenheilkunde

Comparison Between Central Corneal Thickness Measurements in Healthy Eyes Using a New Device and 2 Other Methods. Klinik und Poliklinik für Augenheilkunde. R. Khoramnia, J. P. Salgado, C.P. Lohmann, C. Winkler von Mohrenfels.

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Klinik und Poliklinik für Augenheilkunde

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  1. Comparison Between Central Corneal Thickness Measurements in Healthy Eyes Using a New Device and 2 Other Methods Klinik und Poliklinik für Augenheilkunde R. Khoramnia, J. P. Salgado, C.P. Lohmann, C. Winkler von Mohrenfels All authors have no financial interest in the subject matter of this poster. ASCRS 2011

  2. Klinik und Poliklinik für Augenheilkunde Purpose • The TMS-5 (Tomey) is a new device for the examination of the anterior eye segment combining Placido- and Scheimpflug-Technology. The purpose of this study was to compare central corneal thickness (CCT) measurements using TMS-5, LenStar/Allegro Biograph (Haag-Streit/WaveLight), and the gold standard ultrasonic pachymetry(Pachymeter SP-3000, Tomey). SP-3000 Foto: www.eyenovation.de TMS-5 Foto: www.ophthalworld.de Allegro Biograph/LenStar Foto: www.wavelight.com

  3. Klinik und Poliklinik für Augenheilkunde Material and methods 48 eyes of 24 healthy volunteers were included in this comparative study. In all eyes, CCT was measured with the TMS-5 (Tomey, Nagoya, Japan), LenStar (Haag-Streit AG, Koeniz, Switzerland)/Allegro Biograph (WaveLight AG, Erlangen, Germany), and ultrasonic pachymetry (Pachymeter SP-3000, Tomey, Nagoya, Japan). The values obtained from the different devices were compared using Bland-Altman plots and linear regression.

  4. Klinik und Poliklinik für Augenheilkunde Results I The mean CCT readings with the TMS-5, LenStar/Allegro Biograph, and ultrasound were 516.6 µm, 535.7 µm, and 543.6 µm, respectively. Regression analysis showed a high correlation between the values obtained with the TMS-5 and the LenStar/Allegro Biograph (r=0.950, p<0.001) and the values obtained with the TMS-5 and ultrasound (r=0.918, p<0.001).

  5. Klinik und Poliklinik für Augenheilkunde Results II Compared to the LenStar/Allegro Biograph and ultrasound, the TMS-5 underestimated the CCT. The mean differences were -19.1 µm compared to the LenStar/Allegro Biograph and -27.0 µm compared to ultrasound as shown in the Bland-Altman plots.

  6. Klinik und Poliklinik für Augenheilkunde Conclusion • Regression analysis showed a high correlation between the values obtained with the TMS-5 and the LenStar/Allegro Biograph and the values obtained with the TMS-5 and ultrasound. • However, the TMS-5 underestimated the CCT compared to the LenStar/Allegro Biograph and ultrasound. • Therefore, the TMS-5, LenStar/Allegro Biograph, and ultrasound should not be used interchangeably for the measurement of CCT.

  7. Klinik und Poliklinik für Augenheilkunde Name der Klinik Contact: Klinikum rechts der Isar Tel.: +49 89 4140 – 2310 Technische Universität München Fax: +49 89 4140 – 4076 Klinik und Poliklinik für Augenheilkunde Email: augenklinik@lrz.tum.de Ismaninger Str. 22 www.med.tum.de 81675 Munich www.augenklinik.med.tum.de GERMANY

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