1 / 2

PPP1R11

8. (a). 7. PPP1R11. 6. 5. 4. 3. 2. 1. 8. 7. PPP1R10. 6. 5. 4. 3. 2. 1. 8. 7. TUBB. 6. 5. 4. 3. 2. 1. 8. 7. BAT1. 6. (b). 5. 4. 3. 2. 1. 0. 8. Relative mRNA to those in normal cerebella. 7. Relative mRNA to those in normal cerebella. BAT2. 6. 5. 4.

teenie
Download Presentation

PPP1R11

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. 8 (a) 7 PPP1R11 6 5 4 3 2 1 8 7 PPP1R10 6 5 4 3 2 1 8 7 TUBB 6 5 4 3 2 1 8 7 BAT1 6 (b) 5 4 3 2 1 0 8 Relative mRNA to those in normal cerebella 7 Relative mRNA to those in normal cerebella BAT2 6 5 4 3 0 2 1 0 8 Relative mRNA to those in normal cerebella 7 Relative mRNA to those in normal cerebella CSNK2B 6 5 4 3 0 2 1 0 8 Relative mRNA to those in normal cerebella Relative mRNA to those in normal cerebella 7 BRD2 6 5 4 3 0 2 8 1 7 HMGA1 0 6 5 Relative mRNA to those in normal cerebella Relative mRNA to those in normal cerebella 4 3 2 1 0 NC1 NC2 NC3 NC4 NC5 NC1 NC2 NC3 NC4 NC5 D341 D283 D384 D425 D458 D341 D283 D384 D425 D458 DAOY DAOY ONS76 ONS76 Normal cerebella Normal cerebella MB cell lines MB cell lines Supplementary Figure S1

  2. Supplementary Figure S1. Recurrent chromosomal alterations in medulloblastoma and expression of 8 selected candidate genes that are located at 6p21.33-6p21.31 in medulloblastoma cell lines and normal cerebellar samples. (a) Agilent whole human genome 44K CGH microarray was used to determine genetic alterations of four MB cell lines (DAOY, ONS76, D283 and D341) and eight clinical samples. The data were analyzed using Z-score algorithm with 4 as threshold level for detection of chromosomal aberration and 2Mb as window size. The recurrent chromosomal aberrations (>50% of MB samples) are tabulated. (b) Results of quantitative RT-PCR of 8 selected candidate genes at 6p21.33-6p21.31 for 7 MB cell lines and 5 normal cerebellar samples. Relative fold changes of the mRNA levels of the genes to the mean level of normal cerebellar samples are presented. Each sample was in triplicate. Columns, means; bars, standard deviations. Supplementary Figure S1

More Related