NC State University The Research Enterprise

1. NC State UniversityThe Research Enterprise Welcome Sun microsystems Matt Ronning. Associate Vice Chancellor and Director Research Administration

2. North Carolina State University Land-grant 22,000 Undergraduates 7,000 Graduate Students 1,600 Faculty Ten Colleges: Agriculture and Life Sciences, Design, Education, Engineering, Humanities and Social Sciences, Management, Natural Resources, Physical and Mathematical Sciences, Textiles, Veterinary Medicine

3. NC State Research Summary • $300M in research expenditures in 2001 • 32nd of all US universities – Science and Engineering • 13th of all US universities in non-Federal sponsored research • 8th of all US universities in Industry sponsored research • 5th of all non-Medical US Universities overall • $170M in external sponsored research awards (2002) • Over 60% of faculty engaged in sponsored projects • 59 established research centers – 25 are Membership centers • Over 2700 graduate students supported on paid appointments • Over 60 integrated Centennial Campus research partners

4. Sponsored Program Portfolio

5. IP Disclosures

6. IP Licenses

7. NC State Licenses & Royalties Year Licenses Royalty Income (millions) 1997 13 $3.16 1998 39 $4.28 1999 83 $7.76 * 2000 47 $2.02 2001 51 $3.55 2002 44 $3.69 * Includes a one-time ~$5 million payment

8. NC State Start-Up Companies(based on technologies developed in whole or in part, at NC State) • Environmental Machine Systems, Inc. • Togabi Technologies, Inc. *** • AgRenaissance Software, LLC • Quantum Logic Devices • BioResource International, Inc. *** • Kyma Technologies, Inc. • Zetta Core, Inc. *** • SolarAmp, LLC • Insect Biotechnology, Inc. • Micell Intergrated Solutions • SharpVista • Norcarex Bio Corporation • BioMarck Pharmaceuticals • Neos Discovery, Inc. • Nanovector Incorporated • Noven Pharmaceuticals, Inc. • ArrayXpress, Inc. *** • Allasso Industries, Inc. *** • Super Soil Systems USA, Inc. • HDF Technologies, Inc. • Cree Research (public) • Embrex, Inc. (public) • Biolex, Inc. *** • Origen Therapeutics, Inc. • LipoScience, Inc. • SpaceNet, Inc. • Biotechnologies for Horticulture, Inc. • 3-Tex, Inc. *** • Silicon Semiconductor *** • AlphaVax, Inc. • RCS Technologies • Southeast Tillage, LLC • 22nd Century Limited • SentriSystems, Limited *** • Nitronex Corporation *** • Premitec, Inc. *** • Tribofilm Research, Inc. • Prime Color Software, Inc. • OC3, Inc.

9. NC State Start-UP Summary • 43 Start-Up Companies • 2 publicly traded companies • 39 active companies • 4 defunct companies 12 companies on Centennial Campus • FY 2001—7 new companies • FY 2002—4 new companies • FY 2003 to date—5 new companies

10. NC State’s Centennial Venture Partners • Centennial Venture Partners (CVP) = Fund I • Established in September, 1998 • Sponsored by NC State • $10 million venture capital fund • NC State Endowment & Foundations • Seed and early-stage companies • Pre-Seed Business Formation Program ($15-75k) • Centennial Campus incubator • Focused on NC State affiliation • Intellectual Property • Sponsoring Research • Centennial Campus • Graduates/Students Follow on fund: Academy Funds

11. Partners in Negotiation