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The Health theme Framework Programme for Research FP7

The Health theme Framework Programme for Research FP7. Kevin McCarthy Head of Sector Public Health Directorate Health DG Research – European Commission. Outline today…. The 7 th Framework programme (FP7) Rationale and approach Basic principles Structure Pillar 3

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The Health theme Framework Programme for Research FP7

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  1. The Health themeFramework Programme for Research FP7 Kevin McCarthy Head of Sector Public Health Directorate Health DG Research – European Commission

  2. Outline today… The7th Framework programme (FP7) • Rationale and approach • Basic principles • Structure • Pillar 3 • Outcome of first calls • Present call for proposals • Some projects

  3. N.B.: The European Commission currently manages about 5% of total public spending in R&D in the European Union. The EU currently invests about 1.9% of GDP in research EU Research Policy -Competitiveness, Quality of Lifeand Support to EU policies The key objective of EU Research research policy (Art. 163 & 178 of the Treaty): “the strengthening of the scientific and technological bases of Community industry“ and “promoting all research activities deemed necessary for other policies”. The core objectives for Health research in FP7 are “improving the health of the European citizens and increasing the competitiveness of the European health related industries and businesses…” with emphasis on “translational research”.

  4. FP7 budget (2007-2013): €55 billion = ~6% of public R&D investment in Europe

  5. Cooperationprogramme:thematic areas (€32.4 billion)

  6. Collaborative research in FP7: The Cooperation programme Thematic Priorities • Health 6.1 • Food, agriculture, fisheries and biotechnology 1.9 • Information and communication technologies 9.1 • Nanosciences, nanotechnologies, materials and new production technologies 3.5 • Energy 2.3 • Environment (including climate change) 1.9 • Transport (including aeronautics) 4.2 • Socio-economic sciences and the humanities 0.6 • Security & 10. Space 2.8 Total for collaborative research €32.4 billion

  7. Collaborative researchin the Health theme • Main policy drivers: • Improving health of European citizens • Increasing competitiveness of European health-related industries and businesses • Addressing global health issues, including emerging epidemics Budget: • €6.1 billion over 7 years (2007-2013)

  8. Collaborative research across borders and other barriers • betweencountries: • multinational consortia, with at least 3 partners from 27 EU Member States (MS) + Associated Countries (AC) eg: Albania, Croatia, FYROM, Iceland, Israel, Liechtenstein, Montenegro, Norway, Serbia, Switzerland, Turkey. • researchers from any country in the world can participate, from industrialised countries and from developing countries. eg: Argentina, Australia, Brazil, Canada, China, India, Japan, Korea, New-Zealand, Russia, South-Africa, USA, … … … • between different types oforganizationsPublic & private sector: universities, research centres, large companies, Small and medium-sized enterprises (SMEs), etc. • betweendisciplines: multidisciplinary, translational research

  9. Scientific excellence at European level From policy to funding the best research projects: • The policy for Health research is described in the FP7 specific programme (available on CORDIS) • Each year, a work programme is prepared by the EC, with the Advisory Group and in consultation with the Programme Committee • Through calls for proposals the EC invites researchers from all Europe and beyond to submit their proposals • The very best projects are selected on the basis of evaluation by independent experts (peer review) • After negotiation of a grant agreement, a project is funded for 2-5 y.

  10. Submission & evaluation Basic principles: • annual calls – single-stage or two-stage • eligibility check (partners, limits, scope, deadline) • evaluation by panels of independent expertsoverseen by Independent Observers • 3 criteria: Thresholds: • Science & Technology excellence 3/5 • Implementation & Management 3/5 overall • Potential Impact 3/5 10/15 • feedback: Evaluation Summary Reports (ESRs)

  11. Commission: final ranking list and decision Evaluation procedure Proposal submission Eligibility check IER/IAR eligible 1. Individual evaluation not eligible: exclusion 2. Consensus Group meeting CR + ESR If below threshold If above threshold Consensus Report 3. Panel Evaluation Ethical review (if necessary) Evaluation Summary Report Priority list Commission decision Report Rejection Reserve list Negotiation

  12. Funding schemes in the Health theme (3rd call) Funding schemes upper limits min. partners Large-scale integrating project (CP-IP)* €12m ≥3 Network of Excellence (NoE) €12m ≥3 Small- or medium-scale focussed research project (CP-FP) €3m or €6m ≥3 Coordination action (CA)** €1.5m ≥3 Support action (SA)** €0.5m ≥1 * for CP-IPs there is also a lower limit to the requested EC grant: €6m.** for CAs and SAs there are some exceptions to the upper limit. Warning: the limits for minimum and maximum requested EC grant and for the minimum number of partners are eligibility criteria !

  13. Collaborative Project (CP) – small or medium scale • Designed to generate knowledge to improve European competitiveness and to meet the needs of society or Community policies • To support research, development & demonstration activities of a more limited scope than required by large scale CPs • well defined, focused research and technological development • demonstration, where applicable • project management

  14. Coordination Action • Designed to promote & support the networking & coordination of research & innovation activities at national, regional & European level over a fixed period • Establishing in a coherent way coordinated actions – Programme of work: • - Coordination activities • - Project management activities • CA do not conduct S&T research!

  15. Support Action • Designed to support the implementation of the programme: • To complement the other FP6 instruments • To help to prepare future EU policy activities • To stimulate, encourage & facilitate the participation of e.g. SMEs or organisations from the ACS • May combine two types of activities: • - Support activities • - Consortium management activities • SA do not conduct S&T research!

  16. The Health themeStructure pillar 3: Optimising the delivery of health care pillar 2: Translating research for human health pillar 1: Biotechnology, generic tools & technologies for health cross-cutting issues: child health,the health of ageing population gender-related health issues Activity (pillar) 4: Other actions across the theme

  17. Collaborative researchin the Health theme • 1:Biotechnology, generic tools and technologies • High-throughput research • Detection, diagnosis and monitoring • Predicting suitability, safety and efficacy of therapies • Innovative therapeutic approaches and interventions

  18. Collaborative researchin the Health theme • 2:Translating research for human health • Integrating biological data and processes: large-scale data gathering, systems biology • Research on the brain and related diseases, human development and ageing • Translational research in major infectious diseases • Translational research in other major diseases

  19. Collaborative researchin the Health Theme • Pillar 3:Optimising the delivery of health care to citizens • Translating clinical research into clinical practice • Quality, efficiency and solidarity of health care systems • Enhanced health promotion and disease prevention • including international cooperation in public health & health systems

  20. Collaborative researchin the Health Theme i) Translating clinical research into clinical practice: Better use of medicines, behavioural and organisational interventions, health technologies; focus on patient safety: to identify the best clinical practice to understand decision making in clinical settings in primary and specialised care to foster evidence-based medicine and patient empowerment

  21. Collaborative researchin the Health Theme ii) Quality, solidarity and sustainability of health systems Basis for countries to adapt their health systems taking into account national contexts and population characteristics Organizational, financial and regulatory aspects Implementation – best practice Outcomes - effectiveness, efficiency and equity Special attention on investment issues and human resources

  22. Collaborative researchin the Health Theme iii)Enhanced Health Promotion & Disease Prevention: Evidence for best public health measures in terms of life style interventions; focus on the wider determinants of health and how they interact at the individual and community level Diet, stress, tobacco, physical activity, nutrition, inequalities Mental health to be addressed in life-course perspective

  23. Collaborative researchin the Health Theme The Third Pillar: a completely new activity – health policy driven aims at developing new research methods to generate a sound scientific basis to underpin informed policy decisions on health systems to achieve more effective and efficient evidence-based strategies of health promotion, disease prevention, diagnosis and therapy in a context set by the overarching values of universality, access to good health care, equity and solidarity aiming to make provision that is patient-centred and responsive to individual need Users: EC, MS, WHO, OECD, clinicians, patients, other stakeholders

  24. Identifying priority areas for research is influenced by a range of factors including … • EU Health Strategy & 2nd Programme of Community Action in the field of Health (2008-13) • DG SANCO policy initiatives – patient mobility, cross-border care, health services, health strategy, centres of reference, patient safety, mental health, organ transplantation, urban health, indicators … • European stakeholders – Health Forum, EHFG-Gastein, platforms, councils, … • Member States and the High Level Group on Health Services and Medical Care and various sub groups

  25. Other operational DGs concerned – DG COMP, DG EMPL, DG EAC, DG DEV, DG AIDCO, DG REGIO, DG ENV, DG TRADE, DG ENTR, EUROSTAT, … • International dimension - WHO (Regional Office & HQ) • Wider context of economic reform and growth – importance of health care as a driver of growth and employment locallyNot forgetting of course - • FP7 mechanisms (Advisory Group, Programme Committee, NCPs …) • Project development, feedback as well as project results scientific communities, conferences, workshops, consultations … … influencing factors …

  26. Scientific excellence at European level Topics selection: • FP6 and FP7 actions are taken into consideration • Workshops and conferences with scientific communitiy and others • Early input from MS & AC (strategic priorities) • Topics are drafted by the Commission services, to implement FP7. • Not all topics / areas can be opened at any one time:some areas are closed in some call, emphasis placed on others • Trying to have a structuring effect on European research

  27. Scientific excellence at European level Indicative roadmap : • Strategic reflections (…- October) • Hearing with Cabinet (early November) • Meeting Advisory Group (24 November) • 1st Draft sent to PC (Programme Committee) (early December) • Meeting with PC to discuss draft (12 January 2009) • Updated work programme sent to PC for final comments (February) • Work programme finalised (March) • Internal consultations (April) • Interservice consultation (May) • PC consultation (June) • Written procedure (July) • Publication (end-July) or early September • Deadline December 2009

  28. Key figuresoutcome of 1st & 2nd calls 20072008 (call 2007-A, April 2007) (call 2007-B, Sept. 2007) • budget: € 635 million (2007) € 567 million (2008) • proposals received: 914 902 • proposals evaluated: 893 (ineligible 21) 865 (37) • proposals selected: 152 (+1*) 167 (+5*)% of proposals evaluated: 17% 19% (20%) • av. grant per participant: €412,000 €334,000 * from reserve lists 2007-2008: 325 projects funded with > €1.2 billion

  29. Health theme in FP71st call: €641m, 153 proposals pillar 3: Optimising the delivery of health care pillar 2: Translating research for human health pillar 1: Biotechnology, generic tools & technologies for health 23 proposals: €143m 110 proposals: €476m* closed Activity (pillar) 4: Other actions across the theme 20 proposals: €20m13.7 € of which *plus €2m for ERA-Net on Cancer

  30. Health theme in FP72nd call: €577m: 172 proposals pillar 3: Optimising the delivery of health care pillar 2: Translating research for human health pillar 1: Biotechnology, generic tools & technologies for health 26 proposals: €109m 71 proposals: €280m 38 proposals: €88m Activity (pillar) 4: Other actions across the theme 37 proposals: €100m,incl. €44m & €25m

  31. Optimizing the delivery of healthcare to European citizens 2nd call • Comments across the activity: • Large number of proposals (177) for the 28 topics of this activity • Quality of proposals varied considerably • this new activity was open for the first time • new funding opportunity in a generally underfinanced technical area • few established Europe-wide research consortia • Successful proposals: • responded specifically to the topic • had broad European coverage • Unsuccessful proposals: • weak description of methodology • lacked the required multidisciplinarity • appeared as resubmissions from neighbouring programmes (PHP, ICT)

  32. 3.1 Translating the results of clinical research into practice2nd call • Topics in second call: • Implementation of research into healthcare practice (FP) • Self-medication and patient safety(FP) • Patient Safety Research Network (CA) • Improving clinical decision making (FP) • Better use of medicines (FP) • Continuity of clinical care (FP) • Patient self-management of chronic disease (FP) • Outcome of evaluation • 80 proposals evaluated, 21 (26%) above threshold • Two topics not covered.

  33. 3.1 Translating clinical research into practice 3rd call • Topics proposed topics for 3rd call : • Patient Safety: Effective implementation of prevention strategies for healthcare associated infectionsFunding scheme: CP-FP, max. € 3m. (1 or more projects) • Improve quality and safety of hospital careFunding scheme: CP-FP, max. € 3m. (1 or more projects) • Complementary and alternative MedicineFunding scheme: Coordination Action, max. € 1.5m. (max. 1 project) • Improved treatment of chronic diseases in developingcountriesFunding scheme: CP-FP, max. € 3m. (1 or more projects)

  34. 3.2 Healthcare systems2nd call • Topics in second call: • Evaluation of disease management programmes (FP) • Health systems and long term care of the elderly (FP) • Mobility of health professionals (FP) • Health care human resource planning in nursing (FP) • Clinician working time and patient safety (FP) • Health outcome measures and population ageing (FP) • Trends of population health (FP) • European system of Diagnosis-related groups (FP) • Outcome of evaluation • 54 proposals evaluated, 24 (44%) above threshold • Two topics not covered

  35. 3.2 Healthcare systems3rd call • Topics proposed topics for 3rd call : • Organisation of dementia careFunding scheme: CP-FP, max. € 3m. (1 or more projects) • Health care outcomes and cost-benefitsFunding scheme: CP-FP, max. € 3m. (1 or more projects) • Primary care quality linkage to costsFunding scheme: CP-FP, max. € 3m. (1 or more projects) • Impact of cross border collaboration on health servicesFunding scheme: CP-FP, max. € 6m. (1 or more projects)

  36. 3.2 Healthcare systems3rd call • Topics proposed for 3rd call : • Research access to comparable health care dataFunding scheme: Coordination Action, max. € 1.5m. (max. 1 project) • Scoping study to address the methodological challenges ofquantifying the socio-economic burden of brain diseasescompared to other major diseasesFunding scheme: Support Action, max. € 0.5m. (max. 1 project)

  37. 3.3 - Health promotion and disease prevention 2nd call • Topics in second call: • Promoting healthy behaviour in children and adolescents • Interventions addressing the gradient of health inequalities • Public health interventions addressing the abuse of alcohol • Evaluation of suicide prevention strategies in European countries • Improve vaccination coverage • Outcome of evaluation • 40 proposals evaluated, 17 (42%) above threshold • Two topics not covered

  38. 3.3 - Health promotion anddisease prevention 2nd call • Remarks on the outcomes of 2nd call: • substantial interest and broad coverage of topic 3.3-1 “Promoting healthy behaviour in children and adolescents” • two topics were not covered: • none of the 2 proposals submitted to 3.3-5 “Improve vaccination coverage” were successful. Due to the importance of this research topic the evaluators suggested to republish this topic in a later work programme • the only proposal submitted to 3.4-7 “Mental health research conference” was not successful

  39. 3.3 – Health promotion and disease prevention 3rd call • Topics proposed for 3rd call : • Child and adolescent mental healthFunding scheme: CP-FP, max. € 3m. (1 or more projects) • Environmental prevention of substance abuse by adolescentsFunding scheme: CP-FP, max. € 3m. (1 or more projects) • Ageing cohortsFunding scheme: CP-IP, max. € 12m. (max. 1 project) • Birth/Mother-Child Cohorts co-ordinationFunding scheme: Coordination Action, max. € 1.5m. (max. 1 project) • European child health research platformFunding scheme: Coordination Action, max. € 1.5m. (max. 1 project) • Planned IP on a Health Examination Survey postponed to WP2010

  40. Optimising the delivery of healthcareto European citizens 2nd call • 3.4 – Horizontal CA & SA • Topics in second call successful proposals: • Disease networks of centres of reference Scoping study (SA) • Effectiveness of health investments Scoping study(SA) • Patient mobility and access to information. Scoping study (CA/SA) • Brokering research into policy Scoping study (SA) • A road-map for ageing research(CA/SA) • Health Services Research conference(SA) • No succesful proposals: • Mental health research conference(SA) • Public Health intervention research conference(SA)

  41. EIS – European implementation score for measuring implementation of healthcare practice using vascular disease as an example, will focus on stroke COURAGE – validated measures of health & health related outcomes for an ageing population TEMPEST – investigates how personal & environmental approaches may complement each other in order to develop more effective preventive interventions that will encourage young people to develop a health lifestyle GRADIENT – focusing on effective actions to reduce the gradient in health inequalities, particularly for families & children Some successful FP7 proposals

  42. EUROVAQ – determining the monetary value of quality life adjusted year (QALY) across a number of European States EPIC – European prospective investigation into cancer, chronic diseses, nutrition & lifestyle EUROCADET - Impact iof key determinants on the current & future burden of cancer in Europe EURO-PREVOB – Tackling the social & economic determinants of nutrition and physical activity for the preventio of obesity in Europe HOPE – Health promotion through obesity prevention across Europe MHADIE - Aims to demonstrate the utility and feasibility of ICF model in measuring different types and prevalence of impairments and limitations Not forgetting on-goingFP6 projects …

  43. Key factorsfor success in applying for FP7 funding Competition is tough - only the best projects get funded • the proposal must be in scope with the topic and the work programme (not wishful thinking) • the consortium of partners must be excellent and appropriate for the task (select the right partners) • the proposal must address all 3 criteria, • convince the evaluators (don’t rely on reputation), • and, of course, respect the basic rules.(deadlines, n° participants, ceilings, length, ethics, …)

  44. The Health Directorate Director (acting) – Dr. Manuel Hallen: Medical and Public Health Research unit (F2) Head of unit: Dr. Manuel Hallen (manuel.hallen@ec.europa.eu) Deputy Head of Unit: Dr. Maria Vidal (maria-jose.vidal-ragout@ec.europa.eu) Head of sector Public Health: K. McCarthy (kevin.mccarthy@ec.europa.eu) Infectious Diseases unit (F3) Head of unit: Dr. Alain Vanvossel (alain.van-vossel@ec.europa.eu) Deputy Head of unit: Dr. Anna Lönnroth (anna.lonnroth@ec.europa.eu) Head of IMI sector: Dr. Irene Norstedt (irene.norstedt@ec.europa.eu) Genomics and Systems Biology unit (F4) Head of unit: Patrik Kolar (patrik.kolar@ec.europa.eu) Deputy Head of unit: Dr. B. Mulligan (bernard.mulligan@ec.europa.eu) Health Biotechnology unit (F5) Head of unit: Dr. Arnd Hoeveler (arnd.hoeveler@ec.europa.eu) Coordination unit (F1) Head of unit: Stéphane Hogan (stephane.hogan@ec.europa.eu) Admin. & Finance unit (F6)Head of unit: Georgios Zisimatos(georgios.zisimatos@ec.europa.eu)

  45. Contacts & Information FP7 Health web site: http://cordis.europa.eu/fp7/health NCPs: http://cordis.europa.eu/fp7/health/support_en.html Registration as an Expert: https://cordis.europa.eu/emmfp7/ Fact Sheets: http://ftp.cordis.europa.eu.pub/fp7/docs/healthfacts_en.pdf FP6 projects database: www.lifecompetence.eu SME participation: Dr. Ludovica SerafiniTel. +32 2 295 6759 – Email:ludovica.serafini@ec.europa.euwww.smesgohealth.org International Cooperation: Dr. Indridi BenediktssonTel. +32 2 299 3137 – Email: indridi.benediktsson@ec.europa.eu

  46. Thank you ! • EU – Member States (n = 27) • Candidate/Accession countries • Croatia • Turkey • Countries associated with the FP • Iceland • Israel • Norway • Switzerland

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