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67 years old man Asymptomatic left solid renal tumor of 6 cm.

67 years old man Asymptomatic left solid renal tumor of 6 cm. Radical nephrectomy Clear cell renal cell carcinoma Grade II Fuhrman grading Focal invasion fat tissue sinus Category pT3a. UROLOGIST COMMENTS. PATHOLOGIST COMMENTS. TUMOR-KIDNEY INTERFACE.

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67 years old man Asymptomatic left solid renal tumor of 6 cm.

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  1. 67 years old man Asymptomatic left solid renal tumor of 6 cm. Radical nephrectomy Clear cell renal cell carcinoma Grade II Fuhrman grading Focal invasion fat tissue sinus Category pT3a

  2. UROLOGIST COMMENTS

  3. PATHOLOGIST COMMENTS

  4. TUMOR-KIDNEY INTERFACE Tumoral psedocapsule

  5. TUMOR-KIDNEY INTERFACE Tumoral psedocapsule

  6. TUMOR-KIDNEY INTERFACE Tumoral psedocapsule * *

  7. TUMOR-CAPSULE INTERFACE Kidney capsule

  8. TUMOR-CAPSULE INTERFACE Kidney capsule

  9. KIDNEY-RENAL SINUS INTERFACE No Kidney capsule

  10. TUMOR-RENAL SINUS INTERFACE

  11. RENAL SINUS

  12. RENAL SINUS

  13. RENAL SINUS

  14. RENAL SINUS Vein wall Bonsib. Modern Pathol. 2007; 20: 44

  15. RENAL SINUS

  16. RENAL SINUS Extrarenal invasion 57% Only Sinus invasion.. 38.6% Sinus+Capsule inv. ... 61.4% Vascular invasion Sinus invasion..... 83% Capsule invasion.. 40% Main renal vein 55% Bonsib. Am. J. Surg. Pathol. 2004; 28: 1594

  17. Vein involvement without stroma invasion 19.5% Bonsib. Am. J. Surg. Pathol. 2004; 28: 1594

  18. Sinus invasion and Fuhrman grading Grade 1 + 2.. 17% Grade 3 + 4... 71% Sinus invasion and Tumoral size Bonsib. Am. J. Surg. Pathol. 2004; 28: 1594

  19. Sinus fat tissue invasion 21% of cases with extra-renal growth J. Urol 2005; 174: 1218-1221 AJSP 2004; 28: 1594-1600

  20. ONCOLOGIST COMMENTS

  21. 63 years old man Asymptomatic rigth solid renal tumor of 7.5 cm. Radical nephrectomy Chromophobe renal cell carcinoma Grade III Fuhrman grading Without invasion Category pT2a

  22. UROLOGIST COMMENTS

  23. PATHOLOGIST COMMENTS

  24. Grados de Fuhrman Carcinomas células claras G1 G2 G3 G4

  25. GRADOS DE FUHRMAN Carcinomas células claras G1 100% 80% G2 60% Disease-specific Survival G3 40% G4 20% 0% 0 60 120 180 Months from Nephrectomy

  26. Grados de Fuhrman Carcinomas cromófobos G1 G2 G3 G4

  27. Grados de Fuhrman Carcinomas cromófobos

  28. Nueva propuesta Carcinomas cromófobos Paner et al. Am. J. Surg. Pathol. 2010; 34: 1233 Grado 1 Con posible “atipia cromófoba” sin anaplasia ni apelotonamiento nuclear

  29. Nueva propuesta Carcinomas cromófobos Paner et al. Am. J. Surg. Pathol. 2010; 34: 1233 Grado 2 Variaciones nucleares Apelotonamiento nuclear focal

  30. Nueva propuesta Carcinomas cromófobos Paner et al. Am. J. Surg. Pathol. 2010; 34: 1233 Grado 3 Clara anaplasia Sarcomatoide

  31. Nueva propuesta Carcinomas cromófobos Paner et al. Am. J. Surg. Pathol. 2010; 34: 1233

  32. Nueva propuesta Carcinomas cromófobos Paner et al. Am. J. Surg. Pathol. 2010; 34: 1233

  33. Nueva propuesta Carcinomas cromófobos Paner et al. Am. J. Surg. Pathol. 2010; 34: 1233

  34. ONCOLOGIST COMMENTS

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