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Congenital wbc disorders

Pathology of Congenital WBC disorders.

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Congenital wbc disorders

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  1. 1 Shashidhar Venkatesh Murthy A/Prof & Head of Pathology College of Medicine & Dentistry Quick PATH Bytes Congenital WBC Disorders

  2. 2 Congenital WBC disorders:  Leucocytosis:  Idiopathic Neutrophilia. Increased neutrophils. Asymptomatic.  Leucopenia:  Ethnic or Benign familial Neutropenia. (Jews, Blacks & Arab)  Cyclical Neutropenia. – cyclical variation in WBC counts.  Kostmann’s syndrome: Congenital agranulocytosis – lack of G-CSF severe neutropenia & severe infections.  Felty’s syndrome: Rheumatoid arthritis & severe neutropenia.  Severe Combined Immunodeficiency: absent T Lymphocytes.  WBC Function disorders:  Chronic Granulomatous Disease: Defective microbicidal function.  Lazy leukocyte syndrome.

  3. “Everyone is a genius. But if you judge a fish by its ability to climb a tree, it will spend its whole life believing it is stupid…!” -Albert Einstein

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