1 / 8

The Microcirculation & Lymphatic System

The Microcirculation & Lymphatic System. Structure of the Microcirculation. Capillary System Metarterioles Precapillary sphincter Large “preferential channels” Small “true capillaries”. Structure of the Microcirculation. Metarteriole. Preferential Channel. Arteriole.

wood
Download Presentation

The Microcirculation & Lymphatic System

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. The Microcirculation & Lymphatic System

  2. Structure of the Microcirculation • Capillary System • Metarterioles • Precapillary sphincter • Large “preferential channels” • Small “true capillaries”

  3. Structure of the Microcirculation Metarteriole Preferential Channel Arteriole Precapillary Sphincter True Arterioles Venule

  4. Structure of the Microcirculation (1 Endothelial Cell Thick) Plasmalemmal Vesicles Endothelial Cell Vesicular Channel? Basement Membrane (Collagen Type I) Intercellular Cleft

  5. Transport Mechanisms • Diffusion • Intercellular Clefts • Plasmalemmal Vesicles • “Tight Junctions” (brain) • Open Junctions (liver) • Fenestra (kidney)

  6. Capillary Vasomotion • Intermittent flow regulated by precapillary sphincters. • Controlled by O2 concentration.

  7. Diffusion through Capillary Membrane • Lipid soluable – through endothelial cell membrane. • Water soluable – through intercellular pores • Size Dependent

  8. Diffusion through Capillary Membrane This figure illustrates that the permeability of substances through capillary membrane decreases roughly with the logarithm of size.

More Related