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1. MedInvents’ concept and products

2. MedInvents Concepts and Products Molecular biology MedInvents Applications and Markets
3. Effects of Sodium Ascorbate (Vitamin C) and 2-Methyl- 1,4- Naphthoquinone (Vitamin K3) treatment on Human Tumor Cell Growth In Vitro 2. Synergism with combined chemotherapy action. De Loecker, W : Janssens, J : Bonte, J : Taper, H S Anticancer Research 1993; 13: 103-6. Morphology Effects of Vitamin C and Vitamin K3 Treatment on Human Tumor Cell Growth In Vitro 1. Synergism of Combined Vitamin C and K3 Action VINCENZO NOTO, MD,* HENRYK S. TAPER, MD,t JIANG YI-HUA, MD,*’$ JAAK JANSSENS, MD,§ JAN BONTE, MD,§ AND WILLIAM DE LOECKER, MD’ Cancer 63:901-906, 1989. Biochemistry J PhJanssens, I Russo, J Russo, J Breitmeyer, M LopezBresnahan.Inhibitory effect of recombinant humanchorionicgonadotropin (rhCG) in metastaticbreastcancer in postmenopausalwomen. Biopsybefore and aftertreatment.Monographs of the National CancerInstitute, 2000. Molecular biology Agendia TiGenix MasterGenix Diagenode
4. MedInvents’ concept Implementing clinical use of personalized diagnostics can stratify patients, give molecular classification of disease, determine the likelihood of occurrence, and recommend the best course of treatment.  These approaches promise to reduce costs in healthcare, improve treatment, and have the potential to provide consumer-driven access to health information.  But how will we acquire tissue to fulfill all these opportunities ? Cambridge Healthtech Institute
5. Anno 2011
6. Powerful weapon But where is the monition ?
7. Obstacles for translational research
8. MedInvents’ technology superiority Innovative technology Right in time for the market Safety & Comfort Accuracy Product portfolio Strong science Patents & certificate Consistency Next generation applications Direct & Frontal Macrobiopsy All soft tissues Easy procedure Less invasive
9. MedInvents’ technology superiority Molecular biology Innovative technology Right in time for the market Safety & Comfort Accuracy Product portfolio Strong science Patents & certificates Consistency Next generation applications
10. MedInvents’ technology superiority Innovative technology Right in time for the market Safety & Comfort Accuracy Product portfolio Strong science Patents & certificates Consistency Next generation applications
11. MedInvents’ technology superiority Innovative technology Right in time for the market Safety & Comfort Accuracy Product portfolio Strong science Patents & certificates Consistency Next generation applications
12. MedInvents’ technology superiority Innovative technology Right in time for the market Safety & Comfort Accuracy Product portfolio Strong science Patents & certificates Consistency Next generation applications Gielen JL, De Schepper AM, Blom R, Van Dyck P, Bosmans JML, Creytens DH, Veryser J, Somville J, Parizel PM. Experience with a novel frontal core biopsy device in soft tissue and bone lesions. Skeletal Radiol 2011; 40 In press – Published online.
13. MedInvents’ technology superiority Innovative technology Right in time for the market Safety & Comfort Accuracy Product portfolio Strong science Patents & certificates Consistency Next generation applications
14. MedInvents’ technology superiority Innovative technology Right in time for the market Safety & Comfort Accuracy Product portfolio Strong science Patents & certificates Consistency Next generation applications
15. MedInvents’ technology superiority Innovative technology Right in time for the market Safety & Comfort Accuracy Product portfolio Strong science Patents & certificate Consistency Next generation applications
16. MedInvents’ technology superiority Proprietary technology ISO 9001-2008 ISO 13485 FDA (13 applications) Reimbursement Several applications Several countries Innovative technology Right in time for the market Safety & Comfort Accuracy Product portfolio Strong science Patents & certificates Consistency Next generation applications
17. MedInvents’ technology superiority Innovative technology Right in time for the market Safety & Comfort Accuracy Product portfolio Strong science Patents & certificates Consistency Next generation applications
18. MedInvents’ technology superiority Innovative technology Right in time for the market Safety & Comfort Accuracy Product portfolio Strong science Patents & certificates Consistency Next generation applications
19. Mirror sampling Creation of mirror samples: Pathology: Formaldehyde 5% Molecular biology: RNALater Biobanking: RNALater Deps control
20. Tissue acquisition for translational research
21. Medinvents’ Products A range of large core soft tissue biopsy needles Based on NEW double rota-cutting technique 8 – 14 Gauge Vacuum system on Single Use Product portfolio: Spirotome Single Use/Reusable Spirotome Cervicore ™ Spirotome MRI ™ Spirotome Bone ™ Spirotome Easy Punch ™ Automated version Handheld or stereotactically positioned Reusable handle controller, disposable 8 – 10 Gauge needles Vacuum assisted system Multiple samples without reinserting
22. Medinvents’ Applications Spirotome™ Breast Thyroid Salivary glands Thoracic wall Abdominal wall Lymph nodes Muscle Liver Coramate ™ Breast Thyroid Salivary glands Thoracic wall Abdominal wall Lymph nodes Muscle Spirotome Spine™ Soft tissues within bone Spirotome Endo™ Laparoscopy (type terBrugge) Uterus (type Campo) Spirotome Cervicore ™ Cervix Uterus Spirotome Bone ™ Soft tissues within bone Spirotome Easy Punch ™ Skin Vulva Spirotome Neuro™ Brain
23. MedInvents’ application domains Oncology Animal health Gynecology Infertility Pharmacological research Regenerative medicine Myocardial infarct Urinary incontinency Knee orthopedics Revalidation medicine
24. MedInvents’ in Gynecology
25. Medinvents’ Clinicians - Prof. Gielen; Antwerpen - Dr. Verjans; Tienen - Prof. Lifrange; Liège - Dr. Steyaert; Brugge - Dr. De Jonge; Genk - Prof. Vergote; Leuven - Prof. Kridelka; Liège Prof. Cusumano; Liège Prof. Bogers; Antwerpen - Dr. Naudts; Antwerpen - Dr. Van Wiemeersch; Antwerpen Dr. Coppens; Geel Dr. Schraepen; Brussel - Dr. Michielsen; Antwerpen - Dr. Opdenakker; Hasselt - Dr. Weyers; Gent - Dr. Cornelis; Tienen Dr. Campo; Leuven Dr. DeGryse; Ieper Dr. De Vlaeminck; Torhout …. - Prof. Petignat; Switserland - Dr. Harries; UK - Dr. Rotenberg; France - Dr. Chersevani; Italy - Prof. Schulz-Wendtland; Germany Prof. Polkowski; Poland - Prof. Russo; USA Prof. Nickers; France Prof. Cabula; Sardinia Dr. Feydi; France Prof. Laredo; France Dr. Sentis; Spain Prof. Palussière; France Dr. terBrugge; The Netherlands Dr. Dijkstra; The Netherlands Dr. Mendoza; Peru Dr. Murta; Brasil Prof. Adapon; Philippines Dr. Yespica; USA …. International Belgium
26. What colleagues say: Dear Sir,I have had the opportunity to use the Spirotome in clinical cases and have been very impressed with the level of control and safety, ease of use, and high quality of samples obtained. My pathologist in the college has examined these samples and was likewise impressed with the high quality of diagnostic information obtainable and lack of crushing artifact as sometimes occurs with other systems such as the Tru-Cut style system. Dr. MB, Knoxville, TN 2010
27. Medinvents’ Device R&D We will continue to develop in the spirit of innovative products, “simple, useful and patient friendly” Continuous input from physicians will have an impact on the development ”Coramate M7” Prototype ready for clinical testing IWT supported project
28. Sales Business Opportunities MedInvent’s technology opportunities: Interventional radiology Breast Thyroid Head & Neck Lymph node Lung Liver Kidney Muscle Bone Vertebroplasty Women’s Health Vulva Cervix Hysteroscopy Laparoscopy Surgery Skin Laparoscopy Bronchoscopy Prostate Neurosurgery Bone Drill Cell transplantation Muscle Chondroblast regeneration Animal Health