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Chapter 05 Promoting Reproductive Health Through an Understanding of Sexually Transmitted Diseases. Human Immunodeficiency Virus/ AIDS. HIV – entry via percutaneous /genital routes Plasma viremia → organ dissemination Progression → acquired immunodeficiency syndrome (AIDS)
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Chapter 05Promoting Reproductive Health Through an Understanding of Sexually Transmitted Diseases
Human Immunodeficiency Virus/ AIDS • HIV – entry via percutaneous/genital routes • Plasma viremia → organ dissemination • Progression → acquired immunodeficiency syndrome (AIDS) • Most women infected by exposure to infected men
Screening Recommendations • CDC – opt-out testing, all patients • ACOG – routine for women ages 19–64 • Provide and document post-test counseling • Conform to HIPAA regulations
HIV + Women: Special Concerns • Psychosocial issues • Gynecologic problems related to immunocompromise • Vulvovaginalcandidiasis • Human papillomavirus • Herpes simplex virus
Chlamydia Trachomatis • Most common bacterial STD • Leading cause of preventable infertility • Complications include ectopic pregnancy, pelvic inflammatory disease • Usually asymptomatic in women
Chlamydia Trachomatis (cont’d) • Diagnosis • Culture • Direct immunofluorescence • Nucleic acid hybridization/amplification (NAAT) • Enzyme immunoassay • Treatment • Antibiotics (e.g., doxycycline, azithromycin)
Gonorrhea • Causative bacterium: Neisseria gonorrhoeae • Second most commonly reported STD • Women often asymptomatic • May progress to pelvic inflammatory disease
Gonorrhea (cont’d) • USPSTF, CDC: Annually screen all sexually active women ages 25 and younger • Testing: culture, nucleic acid hybridization, NAAT (cervical or urine sample) • Treatment: antibiotics (cefixime, ceftriaxone); include partners
Trichomoniasis • Causative protozoan: Trichomonas vaginalis • Most common curable STD in U.S. • May be asymptomatic • Symptoms: frothy vaginal discharge (gray, green) with foul odor
Trichomoniasis (cont’d) • Diagnosis • Wet mount (+ motile trichomonad parasites) • Rapid trichomoniasis test, affirm VP III test • Treatment • Metronidazole; tinidazole • Treat partners simultaneously
Pelvic Inflammatory Disease • Acute infection of uterus, fallopian tubes • May cause scarring, adhesions, blockage • Common causative organisms: C. trachomatis, N. gonorrhoeae • Symptoms: pain, bleeding, N & V • Treatment: combined drug therapy
Human Papillomavirus • Cause of condylomata acuminata • Over 100 viral types identified • Usually asymptomatic, sub-clinical • Vaccine available for certain types • Treatment of external warts: topical chemical agents, cryotherapy, laser surgery, electrosurgery
Herpes Simplex Virus 1 and 2 • HSV-1 associated with cold sores • HSV-2 associated with genital lesions • Occurs more frequently in women • Primary infection: flu-like symptoms, pain, appearance of multiple blister-like lesions • Recurrent outbreaks less severe • Transmission possible during viral shedding
Herpes Simplex Virus (cont’d) • Diagnosis: viral culture, serum testing • Treatment goal: hasten healing, reduce symptoms • Antiviral medications • Complementary care measures • Patient education
Syphilis • Causative spirochetal bacterium: Treponema pallidum • Transmission: sexual intercourse, transplacental (maternal-fetal) • Increased incidence since 2001
Syphilis (cont’d) • Primary: chancre • Secondary: fever, rash, malaise, headache, weight loss, condylomata lata • Tertiary: gummas, joint disease, neurosyphilis, C-V syphilis • Treatment: penicillin G, doxycycline, tetracycline
Hepatitis • Leading cause of liver cancer • Most common reason for liver transplantation • May be caused by Hepatitis A virus (HAV), Hepatitis B virus (HBV), or Hepatitis C virus (HCV)
Hepatitis A Virus • Formerly known as “infectious hepatitis” • Incidence highest in developing countries • In U.S., primarily contracted during overseas travel to affected countries • No specific treatment • Vaccine available
Hepatitis B Virus • Highest incidence in persons 20–49 years • More contagious than HIV • Causes liver disease, may be fatal • Transmission: sexual intercourse, blood-to-blood contact, maternal-fetal transfer
Hepatitis B Virus (cont’d) • Symptoms: fever, fatigue, anorexia, jaundice, N & V, dark-colored urine • Most adults recover completely; 25% become chronically infected • Screen all pregnant women, individuals at high risk • Vaccines available
Hepatitis C Virus • Most common bloodborne infection in U.S. • Formerly called “non-A, non-B hepatitis” • Primarily transmitted via blood-blood contact • Most infected individuals progress to chronic viral hepatitis
Hepatitis C Virus (cont’d) • Newly acquired infection often asymptomatic • Various serum screening tests available • After diagnosis, evaluate liver functioning • Consider Hepatitis B vaccination • Combination therapy for chronic infection
Hepatitis D Virus • Only occurs in individuals already infected with HBV • Clinically indistinguishable from other hepatitis types • Transmitted via body fluids • Perinatal transmission rare
Women With Chronic Hepatitis: Nursing Implications • Education, counseling • Maintain excellent hygiene • Avoid contact with all blood sources • Intimate partners use condoms • Nutritional strategies • Avoid alcohol, tobacco, hepatotoxic medications • Referrals
Chancroid • Causative streptobacillus: Haemophilus ducreyi • Symptoms: painful lesion on labia, dysuria, dyspareunia, inguinal adenopathy • Diagnosis: culture or biopsy • Treatment: antibiotics
Lymphogranuloma Venereum • Causative bacterium: Chlamydia trachomatis • Stage 1 – painless genital ulcer • Stage 2 – lymphadenopathy • Symptoms: cervicitis, salpingitis, fever • Treatment: doxycycline, erythromycin
Granuloma Inguinale • Causative bacterium: Klebsiella granulomatis • Symptoms: painless ulcerative lesions on labia, perineum (no lymphadenopathy) • Diagnosis: history, tissue biopsy • Treatment: doxycycline
Pthirus Pubis • Primarily spread through sexual contact • Typically found attached to pubic hair • Do not transmit disease • Feed on human blood • Treatment: permethrin lotion • Teach patients strategies for lice control
STD Education and Counseling • Create a therapeutic environment • Provide information appropriate to patient circumstances (e.g., age, drug use) • Include partners when possible • Teach strategies to promote genital health