San Diego firm offers Whole Genome Resequencing services

1. San Diego firm offers Whole Genome Resequencing services 1010 Genome, the San Diego based company that offers next generation sequencing and bioinformatics analysis, reports strong demand for its Whole Genome Resequencing services and RNA sequencing services. Popularly known by its acronym WGS, this is used to identify the differences in the DNA of particular individuals with that of a referenced genome. The exercise is to create a catalog of mutations that will help to learn more about genetic backgrounds of individuals. The Director, Research and Products had this to say “WGS is extremely valuable to drill deep into the genetic backgrounds of individuals concerned, and we have witnessed a spate in the demands for these services. At 1010 Genome, we possess the technological capabilities to carry out the massive parallel sequencing and bioinformatics analysis that is necessary for WGS”. Typically, WGS involves sequence library preparation and massive sequencing to extract adequate DNA fragments, which will straddle the whole span of the genome. 1010 Genome, with offices in San Diego and Singapore has an impressive portfolio of services including whole genome sequencing. Cost of all services are reasonable; the company relies on advanced equipment and instrumentation from some of the world’s best known brands for sequencing instrumentation – Illumina, Pacbio and Oxford Nanaopre. With a team of highly trained, brilliant scientists, 1010 Genome has consistently managed to offer superior quality sequencing data in the swiftest possible turnaround time. The WGS data analysis leverages cutting edge tools for detecting data, through advanced QC of the raw sequences. The Director shared additional details of the processes, “After the preprocessing of the raw reads, reading of the alignment with the reference genome needs to be carried out extremely carefully. The mapping and identification of the variants hinges upon this process.” 1010 Genome offers annotated genomes as output of the WGS, which is basically the compilation of information about genomic location and mutations. In VCF format, the annotations report, offers descriptions of various filters in standardized text file format. The specifications subscribe to the Global Alliance for Genomics and Health Data Working Group File Format Team - this is a standard format which makes it easy to interpret.