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HDL-Atherosclerosis Treatment Study (HATS): Lipid Results

HDL-Atherosclerosis Treatment Study (HATS): Lipid Results. Placebo Simvastatin + niacin (S+N). Antioxidant vitamins (AV) S+N+AV. *p<.05 vs baseline. Change, %. *. *. *. *. *. *. *. *. *. *. *. *. *. *. LDL-C. HDL-C. HDL 2 -C. TG. Lp(a). TC.

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HDL-Atherosclerosis Treatment Study (HATS): Lipid Results

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  1. HDL-Atherosclerosis Treatment Study(HATS): Lipid Results Placebo Simvastatin + niacin (S+N) Antioxidant vitamins (AV) S+N+AV *p<.05 vs baseline Change, % * * * * * * * * * * * * * * LDL-C HDL-C HDL2-C TG Lp(a) TC Brown BG et al. N Engl J Med 2001;345:1583-1592.

  2. HATS: Angiographic and Clinical Endpoints S+N Placebo AV S+N+AV 25 20 15 10 5 0 90% reduction +3.9 23.7 21.4 *p<.05 vs placebo 14.3 Composite Event Rate, % Change in Stenosis, % +1.8 * * +0.7 2.6 * -0.4 9 Proximal Lesions Coronary Death, MI, Stroke, or Revascularization Brown BG et al. N Engl J Med 2001;345:1583-1592.

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