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Lasinone (Nitisinone) Capsules A Promising Therapeutic Option for HT-1

Send your inquiry and we will help you calculate the total price to buy Lasinone capsules online and have them delivered to your location. From your side, weu2019ll generally need a prescription letter from your treating physician. In some places, we might also ask for an import permit. We are GDP certified and can facilitate the supply of Lasinone (Nitisinone).

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Lasinone (Nitisinone) Capsules A Promising Therapeutic Option for HT-1

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  1. Lasinone (Nitisinone) Capsules: A Promising Therapeutic Option for HT-1

  2. Values HT-1 or Hereditary tyrosinemia type-1 is a rare, autosomal recessive amino acid metabolism disorder. The inadequacy of fumarylacetoacetate hydrolase (FAH), the final enzyme in the pathway of tyrosine catabolism, causes accumulation of toxic metabolites in the FAH-deficient hepatocytes and proximal renal tubular cells and is subsequently responsible for the liver as well as kidney damage.

  3. Hereditary tyrosinemia type-1 typically manifests in infancy and is mainly characterized by increased plasma tyrosine levels. Liver dysfunction, such as hypoglycemia, vomiting, edema, ascites, irritability and jaundice, is the dominant clinical manifestation in children whose diseases are not detected by newborn screening.

  4. The lifetime probability of occurring Hepatocellular Carcinoma is as greater as 37 percent in survivors without proper treatment, as per previous research. Many individuals also suffer from neurocognitive deficits. If left untreated, the survival in individuals with HT-1 is less than 1 year of life; most of these children die because of liver failure and serious coagulopathy. The medicine Lasinone (Nitisinone) capsules are commercially available in 10 mg, 5 mg, and 2 mg dosage strength for the treatment of patients with HT-1 in combination with dietary restriction of tyrosine and phenylalanine.

  5. Nitisinone (Lasinone) is a competitive inhibitor of HPPD, also known as α-ketoisocaproate dioxygenase (KIC dioxygenase). It is designed to help prevent the accumulation of the catabolic intermediates, which may be turned into the toxic metabolites succinylacetone as well as succinyl acetoacetate. The effect of Lasinone capsules on blocking the catabolism of tyrosine also causes a boost in the levels of plasma tyrosine. Therefore, treatment with Lasinone capsules needs restriction of the dietary use of tyrosine as well as phenylalanine in order to help prevent tyrosine toxicity.

  6. Where to Buy Generic Nitisinone (Lasinone) from India: Send your inquiry and we will help you calculate the total price to buy Lasinone capsules online and have them delivered to your location. From your side, we’ll generally need a prescription letter from your treating physician. In some places, we might also ask for an import permit. We are GDP certified and can facilitate the supply of Lasinone (Nitisinone).

  7. Buy Nitisinone (Lasinone) from THE INDIAN PHARMA (TIP), a certified Lasinone supplier in India. Kindly Call or WhatsApp: +91 8130290915 or dial our TOLL-FREE: 1800-889-1064 to buy this medicinal product through legal channels.

  8. Thank You Contact US: Email: info@theindianpharma.com P: +91-120-4080562, M: + 91 8130290915 Toll Free; 1800-889-1064 Website: https://theindianpharma.com/

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