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tICEC-0942 is a small-molecule cyclin-dependent kinase 7 (CDK7) inhibitor developed for cancer therapy. Preclinical study in Acute Myeloid Leukaemia (AML) models shows that ICEC-0942 effectively inhibits the proliferation of several AML cell lines and patient derived AML cells in vitro (IC50 = 0.15-2.6 u03bcM).
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ICEC-0942 Website: https://www.bocsci.com/icec-0942-cas-1805833-75-3-item-8621.html Address: 45-16 Ramsey Road, Shirley, NY 11967, USA