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gpt

This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.

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gpt

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  1. gpt gpt Official Full Name Official Full Name glutamic-pyruvate transaminase (alanine aminotransferase) Background Background This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase. Synonyms Synonyms GPT; glutamic-pyruvate transaminase (alanine aminotransferase); alanine aminotransferase 1; ALT1; GPT1; AAT1; Alanine aminotransferase; ALAT1_HUMAN; Glutamate pyruvate transaminase 1; Glutamic alanine transaminase 1; Glutamic pyruvic transaminase 1; Glutamic--alanine transaminase 1; Glutamic--pyruvic transaminase 1; GPT 1; OTTHUMP00000228783; glutamic-alanine transaminase 1 Recombinant Recombinant Proteins Proteins  Native Proteins Native Proteins Cell & Tissue Lysates Cell & Tissue Lysates Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price GPT- 2236H Recombinant Human GPT Protein, MYC/DDK-tagged HEK293 Human MYC/DDK +Inquiry GPT- 5304H Recombinant Human GPT Protein, GST- tagged Wheat Germ Human GST +Inquiry

  2. Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price GPT- 1283H Recombinant Human Glutamic-Pyruvate Transaminase (Alanine Aminotransferase), His-tagged E. coli Human His +Inquiry GPT- 26390TH Recombinant Human GPT, His-tagged E. coli Human His +Inquiry GPT-33H Recombinant Human GPT E. coli Human +Inquiry GPT-59H Recombinant Human GPT protein, His- tagged E. coli Human His +Inquiry Gpt-131M Recombinant Mouse Gpt protein, His- tagged E. coli Mouse His +Inquiry Gpt-203M Recombinant Mouse Gpt Protein, His- tagged E. coli Mouse His +Inquiry ALT- 3248R Recombinant Rat ALT, His-tagged E. coli Rat His +Inquiry Gpt-206R Recombinant Rat Gpt Protein, His- tagged E. coli Rat His +Inquiry

  3. Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price GPT- 2676R Recombinant Rat GPT Protein Mammalian Cells Rat His +Inquiry Gpt-294R Recombinant Rat Gpt, His tagged Baculovirus- Insect Cells Rat His +Inquiry Gpt-44R Recombinant Rat Gpt protein, His- tagged E. coli Rat His +Inquiry GPT- 1964R Recombinant Rhesus monkey GPT Protein, His- tagged Mammalian Cells Rhesus Macaque His +Inquiry GPT-204P Recombinant Pig GPT Protein, His/GST-tagged E. coli Pig His/GST +Inquiry Involved Pathway Gpt involved in several pathways and played different roles in them. We selected most pathways Gpt participated on our site, such as Arginine biosynthesis, Alanine, aspartate and glutamate metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with Gpt were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway Name Pathway Name Pathway Related Protein Pathway Related Protein Arginine biosynthesis GOT2A; GLS; NAGS; NOS2B; ASL2; ACY1; GPT2L; NOS3; ybaS; ARG2 Alanine, aspartate and glutamate metabolism ASL; AGXTA; GLUD1B; GLS2; GLUD1; GLS; GFPT1; GLULA; GOT2B; FOLH1 Metabolic pathways

  4. UMPS; GFPT1; ST6GALNAC6; AGXT2; CYP8B1; HADH; GAL3ST1A; MBOAT2; ITPK1A; MTHFS Carbon metabolism PGAM1; SUCLG1; PRPS1; ACADS; SDSL; PKM; CAT; TKT; GPR19; PKLR -Oxocarboxylic acid metabolism BCAT2; GPT2; GOT1; GOT2; ACO1; GOT2A; AADAT; BCAT1; GPT2L; ACO2 Biosynthesis of amino acids GOT1; PYCR2; IDH3G; THA1; PYCR1B; PFKM; PCXB; GLULA; PFKMA; ASL2 Protein Function Gpt has several biochemical functions, for example, L-alanine:2- oxoglutarate aminotransferase activity, pyridoxal phosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Gpt itself. We selected most functions Gpt had, and list some proteins which have the same functions with Gpt. You can find most of the proteins on our site. Function Function Related Protein Related Protein Function Function L-alanine:2-oxoglutarate aminotransferase activity Related Protein Related Protein GPT2L; GPT2; GPT Function Function pyridoxal phosphate binding Related Protein Related Protein GOT1; PYGMB; GOT2; ABAT; SDSL; PHYKPL; CBSB; SDS; GAD2; AGXT2L2 Interacting Protein Gpt has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Gpt here. Most of them are supplied by our site. Hope this information will be useful for your research of Gpt. CDC7; RALA; SASS6 Gpt Related Articles Selleng, S; Selleng, K; et al. Prevalence and clinical implications of anti-PF4/heparin antibodies in intensive care patients: a prospective observational study. JOURNAL OF THROMBOSIS AND THROMBOLYSIS 39:60-67(2015). Zhang, FS; Chen, WQ; et al. Transcriptional activity comparison of different sites in recombinant Marek's disease virus for the expression of the H9N2 avian influenza virus hemagglutinin gene. JOURNAL OF VIROLOGICAL METHODS 207:138-145(2014).

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