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neurotrophic tyrosine kinase, receptor, type 2

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway.

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neurotrophic tyrosine kinase, receptor, type 2

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  1. ntrk2 ntrk2 Official Full Name Official Full Name neurotrophic tyrosine kinase, receptor, type 2 Background Background This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Synonyms Synonyms NTRK2; neurotrophic tyrosine kinase, receptor, type 2; TRKB; trk-B; GP145-TrkB; BDNF/NT-3 growth factors receptor; trkB tyrosine kinase; tyrosine kinase receptor B; tropomyosin-related kinase B; BDNF- tropomyosine receptor kinase B; neurotrophic tyrosine receptor kinase type 2 Recombinant Recombinant Proteins Proteins  Cell & Tissue Lysates Cell & Tissue Lysates Assay Kits Assay Kits Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price NTRK2-379H Recombinant Human NTRK2 Protein, His-tagged E. coli Human His +Inquiry NTRK2-109H Recombinant Human NTRK2, Fc Chimera HEK293 Human Fc +Inquiry NTRK2-157H Recombinant Human NTRK2, His tagged HEK293 Human His +Inquiry

  2. Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price NTRK2-158H Recombinant Human NTRK2, Fc-His tagged HEK293 Human FC/His +Inquiry NTRK2-159H Recombinant Human NTRK2 Protein, Fc-tagged HEK293 Human Fc +Inquiry NTRK2-31620TH Recombinant Human NTRK2 Human +Inquiry NTRK2-31621TH Recombinant Human NTRK2, Fc-tagged Human Fc +Inquiry NTRK2-449H Recombinant Human NTRK2, GST-tagged, Active Sf 9 Insect cells Human GST +Inquiry NTRK2-496H Recombinant Human Neurotrophic Tyrosine Kinase, Receptor, Type 2 NS0 Human N/A +Inquiry NTRK2-718H Recombinant Human NTRK2, GST-His Sf 9 Insect cells Human GST +Inquiry NTRK2-751H Recombinant Human NTRK2 Protein, DDK/His-tagged HEK293 cells Human DDK/His +Inquiry NTRK2-752H Recombinant Human NTRK2 Protein, DDK-tagged Sf9 cells Human DDK +Inquiry NTRK2-87H Recombinant Human NTRK2 protein, Flag-tagged, Biotinylated Insect cell Human Flag +Inquiry Ntrk2-1353M Recombinant Mouse Ntrk2, His tagged HEK293 Mouse His +Inquiry

  3. Cat.# Cat.# Product name Product name Source (Host) Source (Host) Species Species Tag Tag Price Price Ntrk2-359M Recombinant Mouse Ntrk2 Protein, His-tagged Insect cell Mouse His +Inquiry NTRK2-1095R Recombinant Rat NTRK2 Protein, His-tagged HEK293 Rat His +Inquiry NTRK2-4103R Recombinant Rat NTRK2 Protein Mammalian Cells Rat His +Inquiry Ntrk2-7471R Recombinant Rat Ntrk2, Fc tagged HEK293 Rat Fc +Inquiry NTRK2-3118R Recombinant Rhesus monkey NTRK2 Protein, His-tagged Mammalian Cells Rhesus Macaque His +Inquiry NTRK2-1041C Recombinant Canine NTRK2 Protein, Fc-tagged HEK293 Canine Fc +Inquiry NTRK2-6784C Recombinant Chicken NTRK2 Mammalian Cells Chicken His +Inquiry Involved Pathway NTRK2 involved in several pathways and played different roles in them. We selected most pathways NTRK2 participated on our site, such as MAPK signaling pathway, Neurotrophin signaling pathway, Alcoholism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NTRK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway Name Pathway Name Pathway Related Protein Pathway Related Protein MAPK signaling pathway RRAS2; CACNG6; CACNB4A; CACNA1BA; FGFR4; MAPT; MAPK8; CASP3A; ZAK; FASLG

  4. Neurotrophin signaling pathway RHOA; RAP1A; CALML5; NTF4; CAMK2B; MAP3K5; PDPK1; YWHAE; FASLG; MATK Alcoholism HIST1H4I; GRIN2C; GRIN3A; PRKACA; CREB3; HIST2H3C; HIST2H4A; FOSB; HDAC4; HIST1H2AK Protein Function NTRK2 has several biochemical functions, for example, ATP binding, brain-derived neurotrophic factor binding, brain-derived neurotrophic factor-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NTRK2 itself. We selected most functions NTRK2 had, and list some proteins which have the same functions with NTRK2. You can find most of the proteins on our site. Function Function Related Protein Related Protein Function Function ATP binding Related Protein Related Protein ULK3; ABCF2; TTL; AK5; NLRP4E; ERBB3B; OLA1; PFKFB4L; NEK12; UBE2E3 Function Function brain-derived neurotrophic factor binding Related Protein Related Protein NTRK2 Function Function brain-derived neurotrophic factor-activated receptor activity Related Protein Related Protein NTRK2 Function Function neurotrophin binding Related Protein Related Protein NTRK1; NGFR; NTRK2; NTRK3 Function Function protein homodimerization activity Related Protein Related Protein HPGD; IL12B; HOGA1; TCF12; TOP2A; CD247; CRYBA2; CTBP2A; CCL5; NPPC Interacting Protein NTRK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NTRK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NTRK2. saicar; PKM; SORT1; abl-tide; HSP90AB1; NTF4; EGFR; POLR2G; AP1B1; NMNAT1 NTRK2 Related Articles

  5. Pajtler, KW; Mahlow, E; et al. Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells. ONCOTARGET 5:11180-11192(2014). Wessels, JM; Wu, L; et al. The Brain-Uterus Connection: Brain Derived Neurotrophic Factor (BDNF) and Its Receptor (Ntrk2) Are Conserved in the Mammalian Uterus. PLOS ONE 9:-(2014).

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