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thbs1

The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]

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thbs1

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  1. thb thbs1 s1 Official Full Name Official Full Name thrombospondin 1 Background Background The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008] Synonyms Synonyms THBS1; thrombospondin 1; TSP; THBS; TSP1; TSP-1; THBS-1; thrombospondin-1; thrombospondin-1p180 Recombinant Recombinant Proteins Proteins  Native Proteins Native Proteins Cell & Tissue Lysates Cell & Tissue Lysates Others Others Source Source (Host) (Host) Cat.# Cat.# Product name Product name Species Species Tag Tag Price Price THBS1-355H Recombinant Human THBS1 Protein, His- tagged HEK293 Human His +Inquiry THBS1-894H Recombinant Human THBS1 Protein, MYC/DDK-tagged HEK293 Human MYC/DDK +Inquiry THBS1-185H Recombinant Human Thrombospondin 1 Baculovirus- Insect Cells Human N/A +Inquiry

  2. Source Source (Host) (Host) Cat.# Cat.# Product name Product name Species Species Tag Tag Price Price THBS1-2657H Recombinant Human THBS1 protein, His- tagged E. coli Human His +Inquiry THBS1- 31513TH Recombinant Human THBS1 protein, glycosylated Insect cells Human +Inquiry THBS1- 31516TH Recombinant Human THBS1 E. coli Human +Inquiry Thbs1-2658M Recombinant Mouse Thbs1 protein, His- tagged E. coli Mouse His +Inquiry Thbs1-2659M Recombinant Mouse Thbs1 protein, His- tagged E. coli Mouse His +Inquiry Thbs1-2660M Recombinant Mouse Thbs1 protein, His- tagged E. coli Mouse His +Inquiry Thbs1-659M Recombinant Mouse Thbs1 NSO Cells Mouse +Inquiry Thbs1-2661R Recombinant Rat Thbs1 protein, His-tagged E. coli Rat His +Inquiry Thbs1-2662R Recombinant Rat Thbs1 protein, His-tagged E. coli Rat His +Inquiry

  3. Source Source (Host) (Host) Cat.# Cat.# Product name Product name Species Species Tag Tag Price Price Thbs1-2663R Recombinant Rat Thbs1 protein, His-tagged E. coli Rat His +Inquiry Thbs1-2664R Recombinant Rat Thbs1 protein, His-tagged E. coli Rat His +Inquiry THBS1-4319C Recombinant Chicken THBS1 Mammalian Cells Chicken His +Inquiry THBS1-2656C Recombinant Cattle THBS1 protein, His & T7-tagged E. coli Cattle His/T7 +Inquiry Involved Pathway THBS1 involved in several pathways and played different roles in them. We selected most pathways THBS1 participated on our site, such as Rap signaling pathway, p signaling pathway, Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with THBS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway Name Pathway Name Pathway Related Protein Pathway Related Protein Rap signaling pathway MAGI2; GNAI2; KIT; RALGDS; FGF2; FGF19; FPR1; PLCE1; FGF9; RRAS p signaling pathway RRM2B; TNFRSF10B; MDM2; CCNG1; BAX; GADD45BA; Casp3; THBS1; TP53; GADD45AA Phagosome THBS1; ATP6V0E; HLA-DRB1; HLA-DRB3; SEC22BB; CTSL1B; ATP6V1BA; HLA- DMA; HLA-C; BMA2 PIK-Akt signaling pathway PPP2R3A; BRCA1; EPO; HGF; TCL1B4; THBS1; IFNA10; VEGFA; HSP90AB1; PPP2R3C TGF-beta signaling pathway

  4. RBX1; TFDP1A; INHBB; SMAD1; LTBP1; PITX2; RPS6KB1B; FST; BMP7B; CHD Focal adhesion PDGFAA; HRAS; PIK3CG; PDGFC; ACTN3B; COL6A5; HRASB; FYNB; GSK3AA; ELK1 ECM-receptor interaction GP1BB; CD47; COL5A2; Npnt; VTN; COL2A1; LAMB1A; THBS3; FN1A; ITGA9 Malaria KLRC4-KLRK1; TLR9; CD40; TGFB1; IL1B; GYPA; IL-8; SELP; MET; CD81 Proteoglycans in cancer PPP1R12B; PAK1; CBLB; PRKACB; SDC2; TRP53; CAMK2G; TLR2; TGFB2; PIK3R1 MicroRNAs in cancer MAP2K1; ERBB2; NFKB1; APC; TNC; CDC25C; KIF23; CDC25A; TP53; RPTOR Bladder cancer THBS1; RASSF1; CXCL8; DAPK1; MMP9; E2F1; BRAF; RB1; ARAF; MYC Protein Function THBS1 has several biochemical functions, for example, calcium ion binding, collagen V binding, fibrinogen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by THBS1 itself. We selected most functions THBS1 had, and list some proteins which have the same functions with THBS1. You can find most of the proteins on our site. Function Function Related Protein Related Protein Function Function calcium ion binding Related Protein Related Protein SYT2; CABYR; MYL10; HEG; CABP1; CALN1; ANXA11A; PVALB; S100A12; S100A4 Function Function collagen V binding Related Protein Related Protein THBS1; ECM2 Function Function fibrinogen binding Related Protein Related Protein FBLN1; THBS1; MFAP2; ITGA2B Function Function fibroblast growth factor binding Related Protein Related Protein S100A13; FIBPA; FGFBP3; FIBPB; KLB; FGFR3; FGFR1A; FGFBP1; HSPA9; Api5 Function Function fibronectin binding Related Protein Related Protein PLEKHA2; CTSS; ITGAV; MYOC; HSD17B12; SDC4; IGFBP5; SFRP2; MFAP2; IGFBP5A Function Function glycoprotein binding Related Protein Related Protein SDCBP; FBXO6; LGALS1; LACRT; ITGAM; TFRC; DNAJC5; AZGP1; TGFB1; Shh Function Function heparin binding

  5. Related Protein Related Protein APOH; PLA2G5; PRG2; MSTN; COL25A1; CCL23; FMOD; FSTL1; CCDC80; APOA5 Function Function identical protein binding Related Protein Related Protein SMG9; S100A1; DDX58; MBIP; IGF1R; ACADM; PYCARD; AIRE; SOD1; CLPP Function Function integrin binding Related Protein Related Protein ADAMTS13; TLN1; ADAMTS8; COL4A3; ILK; GFAP; PTPN2; FN1A; MMP14; CXADR Function Function laminin binding Related Protein Related Protein LGALS1; LGALS3; ITGA3; TINAGL1; NID1; LYPD5; ITGA7; NCL; AGRN; CTSS Function Function low-density lipoprotein particle binding Related Protein Related Protein PCSK9; COLEC12; CDH13; LIPC; THBS1; SCARF1; CRP; MSR1; SORL1; SCARB1 Function Function phosphatidylserine binding Related Protein Related Protein OSBPL10; ANXA9; OSBPL8; GAP43; SCARB1; RS1; SCIN; RASGRP1; PLCD1; CPNE6 Function Function protein binding Related Protein Related Protein MOAP1; IFT57; SEC31A; EFCAB11; TUBA1B; TBCEL; WDFY2; SPERT; RIPK1; PPP1R9A Function Function proteoglycan binding Related Protein Related Protein THBS1; FCN2; CECR1; CTSS; CTSB; CECR1A; NID1; COL5A1; CTSL1; CTSK Function Function transforming growth factor beta binding Related Protein Related Protein TGFBR3; TGFBR2; LTBP4; THBS1; ACVRL1; TGFB3; VASN; ACVR1; ENG; CD109 Interacting Protein THBS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with THBS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of THBS1. PCOLCE; TGFB1; PLEK; chondroitin_sulfate; dermatan_sulfate; heparin; heparan_sulfate; collagen_i_human; collagen_xi_human; collagen_vi_human; FN1; APP; Col11a1; BGN; TGM2

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