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Cholangiocarcinoma is a rare and heterogeneous malignant neoplasm with epithelial cell origin of biliary duct and histologic and biochemical features of cholangiocyte differentiation. The malignant tumor may arise from any portion of the bile duct i.e., from terminal ductules to the ampulla of Vater, and at the peribiliary glands. <br>
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CHOLANGIOCARCINOMA(CCA) Market Insights, Epidemiology, and Market Forecast- 2028
CHOLANGIOCARCINOMA (CCA) ORIGIN CLASSES BASIS Cholangiocarcinoma (CCA) is coded as intrahepatic bile duct carcinoma (C22.1), extrahepaticbile duct carcinoma (C24.0), Ampulla of Vater (C24.1), overlapping lesion of biliary tract (C24.8) or it involves both intrahepatic and extrahepatic bile ducts (C22.0-C24.1), and Biliary tract unspecified (C24.9). It can be classified anatomically based on tumor location within the biliary tree into intrahepatic (iCCA), perihilar (pCCA), and distal (dCCA) cholangiocarcinoma subtypes. The latter two subtypes were previously grouped as extrahepatic CCA (eCCA), but are now considered distinct entities based upon differences in their tumor biology and management. Cholangiocarcinoma is a rare and heterogeneous malignant neoplasm with epithelial cell origin of biliary duct and histologic and biochemical features of cholangiocyte differentiation. The malignant tumor may arise from any portion of the bile duct i.e., from terminal ductulesto the ampulla of Vater, and at the peribiliaryglands. • DelveInsight © 2019 | All rights reserved
CCA EPIDEMIOLOGY Diagnosed EU-5 Incidence Cholangiocarcinoma total diagnosed incident population in the 7MM was 18,470 in 2017. Among the EU5 countries, Germany had the highest CCA incident population with 4,471cases. US Incidence Prevalence Among all the countries, the higher Cholangiocarcinoma incidence was 6,768cases in the US in 2017. Males are more prone to Cholangiocarcinomaas compared to females among all countries. • DelveInsight © 2019 | All rights reserved
Cholangiocarcinoma Market Outlook 01 02 03 04 05 Cholangiocarcinomamarket size in the 7MM* was found to USD 379.57 million in 2017 for the study period (2017-2028). CCA market size in Germany was found to be highest with USD 82.46 million in 2017, whereas Spain has the lowest share with USD 3.69 million in 2017. Cholangiocarcinoma market size for early stage includes surgery with chemotherapy and chemoradiation therapy. Among 7MM* the United States accounts for the highest CCA market size in comparison with EU-5 and Japan. The launch of various multiple-stage pipeline products will significantly revolutionize CCA market in future. *7MM includes:- United States; EU 5 (Germany, France, Spain, Italy, United Kingdom); Japan. www.website.com 4 • DelveInsight © 2019 | All rights reserved
CCA Emerging Drugs and Companies Drug-Pemigatinib Company-Incyte Corporation Drug-Regorafenib Company- Bayer 03 01 Drug- Ivosidenib Company-Agios Pharmaceuticals Drug-Entrectinib Company-Roche 02 04 • DelveInsight © 2019 | All rights reserved
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