liver cancer treatment in chennai pdf

1. 2/6/24, 5:08 PM Liver Cancer treatment in Chennai Introduction: Notes - Evernote Liver cancer, also known as hepatocellular carcinoma (HCC), is a significant health concern globally, with a considerable burden in Chennai, India. Recognized as one of the leading causes of cancer-related deaths worldwide, liver cancer requires comprehensive treatment strategies to address its complexity and improve patient outcomes. In Chennai, renowned medical institutions offer a multidisciplinary approach to liver cancer treatment, integrating surgery, chemotherapy, radiation therapy, and innovative therapies to provide patients with optimal care. Understanding Liver Cancer: Liver cancer typically arises from hepatocytes, the primary cells of the liver, and can manifest as primary liver cancer or metastatic liver cancer originating from other organs. Chronic liver diseases such as hepatitis B and C, alcoholic liver disease, non-alcoholic fatty liver disease (NAFLD), and cirrhosis significantly predispose individuals to liver cancer. Early symptoms may be nonspecific, including abdominal pain, unexplained weight loss, jaundice, and fatigue, often leading to late-stage diagnoses with limited treatment options. Diagnostic Approaches: In Chennai, diagnosing liver cancer involves a thorough evaluation, including medical history review, physical examination, and imaging studies such as ultrasound, CT scans, and MRI scans. Blood tests to assess liver function, alpha-fetoprotein (AFP) levels, and genetic markers aid in diagnosis and staging. Advanced diagnostic techniques like biopsy may be employed to confirm the presence of cancer and determine its characteristics, guiding treatment planning. Multidisciplinary Treatment Modalities: The treatment of liver cancer in Chennai is comprehensive, involving a multidisciplinary team of specialists collaborating to tailor individualized treatment plans. The primary modalities include: Surgery: 1. Surgical resection: Resection of the tumor along with a margin of healthy tissue is performed when the cancer is confined to a specific area of the liver and the remaining liver function is adequate. Liver transplantation: For patients with advanced liver cancer or underlying liver cirrhosis, liver transplantation offers a curative option, replacing the diseased liver with a healthy liver from a compatible donor. Locoregional Therapies: 2. Radiofrequency ablation (RFA): RFA involves the use of heat energy to destroy cancer cells. It is effective for small tumors and can be performed percutaneously or laparoscopically. Transarterial chemoembolization (TACE): TACE delivers chemotherapy directly to the tumor while blocking its blood supply, reducing tumor growth and improving patient outcomes. Radioembolization: This procedure involves the delivery of radioactive microspheres directly into the blood vessels supplying the tumor, causing localized radiation therapy while minimizing damage to healthy liver tissue. https://www.evernote.com/client/web?login=true#/notes/65b63859-bffb-12df-1a3d-1c42e6eb5abc 1/4

2. 2/6/24, 5:08 PM Notes - Evernote minimizing damage to healthy liver tissue. Systemic Therapies: Chemotherapy: Traditional chemotherapy agents or targeted therapies may be administered orally or intravenously to target cancer cells and inhibit their growth and spread. Immunotherapy: Immunotherapeutic agents such as immune checkpoint inhibitors stimulate the body's immune system to recognize and attack cancer cells, offering promising results in select patients with liver cancer. Palliative Care: Palliative care focuses on alleviating symptoms, improving quality of life, and providing psychosocial support for patients with advanced liver cancer or those not amenable to curative treatments. 3. 4. Innovative Approaches and Clinical Trials: Chennai's medical institutions actively participate in clinical trials evaluating novel therapies, including molecularly targeted agents, immunotherapies, and combination treatments for liver cancer. These trials offer eligible patients access to cutting-edge treatments and contribute to advancing the understanding and management of liver cancer on a global scale. Post-Treatment Surveillance and Follow-Up: After completing treatment for liver cancer, patients undergo regular surveillance to monitor for disease recurrence and assess treatment efficacy. Imaging studies, blood tests, and physical examinations are performed at scheduled intervals, allowing for early detection of recurrence and timely intervention if needed. Patients are also provided with ongoing support and resources to manage treatment-related side effects and optimize their overall well-being. Collaborative Care Approach: The management of liver cancer in Chennai emphasizes a collaborative care approach, involving close coordination among hepatologists, surgical oncologists, medical oncologists, radiation oncologists, interventional radiologists, pathologists, and supportive care teams. This multidisciplinary approach ensures that patients receive comprehensive, evidence-based care tailored to their unique clinical circumstances, with a focus on achieving the best possible outcomes and improving their quality of life. Patient-Centered Care and Support Services: In addition to medical treatment, patients with liver cancer in Chennai have access to a range of support services designed to address their physical, emotional, and psychosocial needs. These services may include nutritional counseling, pain management, palliative care, psychological counseling, support groups, and survivorship programs, fostering a holistic approach to patient care and well-being. Clinical Outcomes and Quality Metrics: Chennai's medical institutions continually evaluate clinical outcomes and quality metrics related to liver cancer treatment to ensure the delivery of high-quality, evidence-based care. Data on treatment efficacy, complication rates, survival outcomes, and patient satisfaction are systematically collected and analyzed, guiding quality improvement initiatives and informing clinical decision-making to optimize patient outcomes. https://www.evernote.com/client/web?login=true#/notes/65b63859-bffb-12df-1a3d-1c42e6eb5abc 2/4

3. 2/6/24, 5:08 PM Notes - Evernote Conclusion: Liver cancer treatment in Chennai encompasses a multidisciplinary approach that integrates surgical, locoregional, systemic, and palliative therapies to provide patients with comprehensive care throughout their treatment journey. With a focus on personalized treatment plans, innovative approaches, collaborative care, and support services, Chennai's medical institutions strive to improve clinical outcomes, enhance quality of life, and advance the field of liver cancer management. Through ongoing research, clinical trials, and quality improvement efforts, Chennai remains at the forefront of liver cancer care, offering hope and healing to patients and their families facing this challenging disease. For more details visit https://drmagnusjayaraj.com/liver-cancer-treatment-in- chennai/ https://www.evernote.com/client/web?login=true#/notes/65b63859-bffb-12df-1a3d-1c42e6eb5abc 3/4

4. 2/6/24, 5:08 PM Notes - Evernote https://www.evernote.com/client/web?login=true#/notes/65b63859-bffb-12df-1a3d-1c42e6eb5abc 4/4