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Dr. Arun Aggarwal is one of the famous doctor of Gastroenterology has studied some cases of ANMS and prepared report so that every one could realise there health problem or can get the review about that <br>
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CASE I 7 year old male with h/o chronic constipation and encopresis Never had formed stools in life, always leaking On regular diet No organic cause of constipation
Physical examination: normal Rectal: full of stools Multiple admissions in past for clean out.
Previous Investigations CBC, BMP: normal Abdominal X ray: fecal loading Barium enema: no transition zone, reduntant colon Anorectal manometry: average resting pressure 69-86, RAIR present at 30 cc, max squeeze pressure at 116/9 mmHg Rectal biopsy: ganglion cells present Colonic transit study: slow transit
Previous medicines Enemas Suppositories Miralax Stimulant laxatives Golytely
Referred from outside hospital for further evaluation before possible colectomy…..
Plan was made for colonic manometry Colonic catheter placed with colonoscopy Colonoscopy: dilated colon
Colonic manometry after Bisacodyl administration showing High Amplitude propagated contractions
Colonic manometry after Bisacodyl administration showing High Amplitude propagated contractions
RESULT: normal colonic manometry PLAN: cecostomy for antegrade enemas; avoid colectomy.
CASE II 7 year old male with chronic constipation and encopresis. No other significant past medical history. No organic cause of constipation. Physical examination: normal
CBC, BMP, Ca, TFT, celiac profile: normal Anorectal manometry and suction biopsy: normal MRI: normal lumbosacral spine, constipation Barium enema: normal
Previous medications: • Miralax • Exlax • Enemas • Suppositories • Clean out in the ER
colonic manometry followed by cecostomy was done in 10/09. Started on antegrade enemas. Continued to have stool retention and encopresis
Admitted for repeated colonic manometry to decide for further management…..
Colonic manometry showing HAPC in proximal colon, none in distal colon
Colonic manometry showing HAPC in proximal colon, none in distal colon
RESULT: normal proximal colonic manometry, no motility in distal colon. PLAN: distal colectomy.