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Many people have never heard of the term hydronephrosis. Thatu2019s because it is only prevalent in around 1% of the general population according to a research paper published by Science Direct. Hydronephrosis can affect both children and adults. In fact, it can even affect babies in the womb; this can be found via prenatal ultrasound. The same study by Science Direct observed that 1 in 100 to 200 fetuses suffered from hydronephrosis. Because of this, finding out that you suffer from hydronephrosis and require surgery might seem daunting. But donu2019t worry about it. You can find hydronephrosis treatment in Delhi without breaking a sweat!
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Antenatal Antenatal Hydronephrosis Hydronephrosis(ANH): Surgical Aspects Surgical Aspects (ANH): Dr Dr Prashant Prashant Jain Sr. Consultant Sr. Consultant Pediatric Surgery & Pediatric Urology Pediatric Surgery & Pediatric Urology Dr BLK BLK Superspeciality Superspeciality Hospital, New Delhi Jain Dr Hospital, New Delhi
Antenatal Hydronephrosis Renal anomalies accounts for 17% of all the congenital anomalies Hydronephrosis is commonest (1-5% of all pregnancies) Management dilemma
ANTENATAL HYDRONEPHROSIS DILATATION OF FETAL RENAL COLLECTING SYSTEM Transient dilatation (41 to 88%) Vesico-ureteric reflux (10 -20%) True Obstruction (20 -50%)
What is True Obstruction??? • Anatomical or Functional impairment in urinary drainage from kidney which ultimately is going to affect the renal function Impairment in Urinary drainage Dilatation Impairment of renal functions
True obstruction Pelvi Ureteric Junction Uretero-vesical Junction Bladder outlet Posterior Urethral Valve
Why diagnostic Dilemma? Transient impairment of urinary flow Permanent impairment of urinary flow IMPORTANT TO DIFFERENTIATE
Evaluation Of ANH Ultrasound Micturiting Cystourethrogram Nuclear renal scan * DRCG * DMSA * DTPA Magnetic Resonance Urography (MRU) - - - -
Antero-Posterior Diameter of Renal Pelvis (Transverse plane)
Definition of ANH by AP(Antero-Posterior) Diameter of Renal Pelvis Mild 4 to <7 mm 7 to <9 mm Moderate 7 to 10 mm 9 to 15 mm Severe >10 mm >15 mm Second trimester Third trimester
Case: Antenatal hydronephrosis Antenatal scan- 32 wks Lt hydronephrosis with dilated pelvicalyceal system; No hydroureter Antero-posterior(AP) diameter of Lt renal pelvis: 13 mm AFI: 9 What Next?? 13mm
Counseling is Challenge….. Is it a transient dilatation or pathological dilatation? What is accurate diagnostic tool? How to prognosticate? How long to follow? When to operate?
Risk Of Postnatal Pathology Mild: 11.8% Moderate:44.1% Severe: 88.3%
Moderate hydronephrosis (Resolution: 40- 50%) CAN NOT BE IGNORED Re-assessment after delivery Will require regular follow up with USG and renal scans Continue pregnancy till term
Post natal Newborn passing urine Bladder not palpable What Next? USG KUB after 48-72hrs AP Diam: 14mm What Next? Chemoprophylaxis USG & DTPA Scan after 1 month of age
ANTENATAL HYDRONEPHROSIS Post Natal USG at 48 -72 hrs Hydro-ureteronephrosis present No hydronephrosis Hydronephrosis present Mild Chemoprophylaxis Early MCU Moderate/severe Repeat USG at 3 months USG at 3, 6, 12 mths Chemoprophylaxis ??MCU DTPA Scan No hydronephrosis No further evaluation B/L HN, BLADDER OUTLET OBSTRUCTION, AND SINGLE KIDNEY NEEDS EARLY EVALUATION
Consider Surgery Split function is < 40% Progressive increase in AP diameter Symptomatic
RK AP DIAMETER LK AP DIAMETER ANTENATAL - 14 MM DAY3 - 14 MM 1MTH - 18 MM DTPA scan 3MTH - 18 MM 6MTH 19 12MTH 19 Advised DTPA scan
Case: Antenatal Hydronephrosis Rt AP of Pelvis diameter of 6 mm 20 wks scan Rt AP diameter of pelvis 8 mm 28 wks scan Rt AP diameter of pelvis 7mm 36 wks scan Before discharge Rt AP of Pelvis diameter of 8 mm Rt AP of Pelvis diameter of 8 mm USG at 1mth USG at 3mth & 1 year No dilatation
Antenatal Scan 32 wks Bilateral hydronephrosis and hydroureter Bilateral AP diameter 7mm Bilateral echogenic kidneys Bladder full; Key hole sign AFI 8
Antenatal Scan: Hydrouretronephrosis Vesico-ureteric reflux Vesico-ureteric junction obstruction Posterior Urethral Valve
Counseling Obstruction at vesico-urethral junction Need for surgery(Endoscopic Fulgaration) Need for long term follow up Risk of ESRD
Case… 37 wks, LSCS, 1.6 kg USG: B/L HN & HU Thinned out renal parenchyma Thickened and distended bladder Catheterised Serum Na: 132 Serum K: 5.3 S. Creatinine:1.6 VBG: Normal Urine C/S: sterile
Post Operataive Stable Polyuria: 5ml/kg/hr(Post operative diuresis) Catheter removed after 72 hrs Polyuria Settled in 7 days Discharged with S.Creatinine of 1meq/l Chemoprophylaxis Anticholinergics (Tropan)
Follow up Intermittent dribbling present Urinary Stream good DMSA: left scarred kidney S.Creatinine : 0.6 Dilatation on USG is less, PVR5 ml Now 2yrs No chemoprophylaxis Needs long term follow up MCU on follow up
Case Ante natal USG s/o left moderate hydronephrosis Repeat USG, dilatation of upper kidney with hydroureter s/o duplex system and ureterocele
CASE Antenatal scan 32 wks Left hydronephrosis AP diam of renal pelvis 11mm Left ureteric dilatation present Right Kidney normal Bladder normal
Post natal Term male newborn;3kg Newborn passing urine Bladder not palpable WHAT NEXT Antibiotic prophylaxis USG KUB after 48-72hrs AP Diam: 11mm;Ureter dilated WHAT NEXT MCU under antibiotic cover
MCU • Rt Grade III VUR
DMSA Scan • Scarred left kidney
Follow up Advice Chemoprophylaxis Early toilet training Avoid constipation Perineal Hygine Growth/BP monitoring Regular Urine examination/ultrasounds/DMSA scan
When to intervene? Recurrent breakthrough UTI Progressive scars in DMSA SCAN Parents choice Endoscopic injection Vs Ureteric Reimplantation
STING technique (Subureteric transurethral injection) 43
Follow Up Chemoprophylaxis stopped Follow up with nephrologist
CARRY HOME MESSAGE Do not ignore ANH even if it is transient Remember AP diameter of pelvis 4/7/10 mm Most ANH just need surveillance Hydronephrosis is not synonymous with obstruction Be positive, supportive, ANH usually have good prognosis.