Ikgdar 100Mg Injection - Uses, Side Effects, Substitutes, Composition And More |MHP

1. Ikgdar-100mg Medicine Overview of Ikgdar-100mg Uses of Ikgdar-100mg Tablet: Ikgdar 100mg injection and hyaluronidase human injection are given alone or combination with another drugs to treat certain types of non-Hodgkin's lymphoma and chronic lymphocytic leukemia (cancer start in WBC). Ikgdar 100mg injection is also used with methotrexate (Otrexup, Rasuvo, Xatmep, others) for the treatment rheumatoid arthritis symptoms in adults that have been already treated with a some type of regimen knowns as tumor necrosis factor (TNF) inhibitor. Ikgdar 100mg injection is a type in a classification of drugs called monoclonal antibodies. Ikgdar 100mg injection is used to killing cancer cells to treat NHL , CLL, rheumatoid arthritis, granulomatosis with polyangiitis, and microscopic polyangiitis by stopping the activity of the part of the immune system which can damage the joints, veins, and other blood vessels and cause damage to organs (heart and lungs). Ikgdar-100mg Side effects of Ikgdar-100mg Tablet Common effects: fever and chills (flu lik symptoms)

2. Less common side effects: Weakness; nausea ; headache; cough ; dyspnea ; pharyngitis How to use Ikgdar-100mg Tablet Ikgdar injection is recommended to administer only through intravenous infusion not by IV push or bolus. PREMEDICATE BEFORE EACH INFUSION First infusion: initially rate of 50 mg/hr is given , in not showing infusion toxicity, rate rised upto 50 mg/hr increments at intervals of 30 min and max of 400 mg/hr. Successive infusion: start at rate of 100 mg/hr, in not showing infusion toxicity, rate raised upto 100 mg/hr increments at intervals of 30 min and max of 400 mg/hr. Premedication with corticosteroids must be considered, if Ikgdar injection combination with CHOP chemotherapy is not given. LOW GRADE OR FOLLICULAR NON-HODGKINS LYMPHOMA: Dose is 375 mg/m2 as an IV infusion. Relapsed treatment : once weeks for 4 or 8 doses administrated. Retreatment for relapsed : once weekly for 4 doses administrated. Previously untreated : administer on day 1 of each cycle of chemotherapy, upto8 doses. In complete or partial response of patient, start with 8 weeks for maintenance following rituximab in combination with chemotherapy completed then administer 8 weeks for 12 dose as a single agent. Non – progression ( following CVP chemotherapy completion 6 – 8 cycles): once weekly for 4 dose at intervals of 6 months and max of 16 dose. Diffuse large B- cell NHL : on day 1 each cycle of chemotherapy upto 8 infusions. CHRONIC LYMPHOCYTIC LEUKEMIA Before starting of FC chemotherapy, dose recommended is 375 mg/m2 followed 500 mg/m2 on day 1 of 2-6 cycles every 28 days. COMPONENT OF ZEVALIN FOR TREATMENT OF NHL: Ikgdar infusion about 250 mg/m2 within 4 hours prior to the administration of Indium-111-(In-111-) Zevalin and Yttrium-90- (Y-90-) Zevalin. Rituxan and In-111-Zevalin 7–9 days before to Rituxan and Y-90- Zevalin administrated. RHEUMATOID ARTHRITIS Ikgdar injection is administer with methotrexate combination

3. Ikgdar injection administrating as two dose of 100mg IV infusion 2 weeks separated. When glucocorticoids administered as methylprednisolone 100mg IV Successive course based on clinical evaluation must administer every 24 weeks,but not early than every 16 weeks. GRANULOMATOSIS POLYANGITIS AND MICROSCOPIC POLYANGITIS Dose of 375 mg/m2 IV infusion weekly once for 4 weeks. When Glucocorticoids treat with methylprednisolone by dose of 1000 mg IV/ day for 1- 3 days and purse by oral prednisone 1 mg/kg/day are recommended for the treatment of symptoms of serious vasculitis . This drug should intiate within 14 days before or with the starting of Ikgdar 100mg injection and may continue during and after the 4 week course with treatment of Ikgdar injection. Safety and not established for subsequent infusion. Take an Ikgdar 100mg injection amount and diluted to final concentration of 1 mg/ml upto 4 mg/ml as infusion (containing either 0.9% Nacl or 5% dextrose in water). Invert gently the bag and mix the solution. Dispose unused drug left in vial. Expert Advice for Ikgdar-100mg Tablets Allgeric condition against Ikgdar 100mg injection or any other medication inform your doctor. Regarding your past medical drug used which include in prescription, non- prescription, vitamins & supplements , nutritional products just inform the doctor. While using Ikgdar 100mg injection do not take any vaccination or immunization without taking advice from doctors. Avoid use ofIkgdar 100mg injection if you are pregnant. It will harm the baby unborn, while using Ikgdar injection use correct birth control to prevent pregnancy and for at least 2 weeks after your treatment ends. Ikgdar 100mg injection may affect the ability to have children in women. Inform your doctor if you planning to pregnant. It is unknown whetherIkgdar 100mg injection passes into breast milk , avoid breast-feed while on Ikgdar injection treatment. Discard the unused drug by asking the advice from doctor or pharmacist.

4. Missed Dosage If you missed a dose take it as soon as possible, if time reach for next dose, then skip missed dose and continue and continue the regular schedule. Do not take extra or 2 dose at a same time. OVERDOSAGE: If overdosage occurs seek immediately to the emergency department or poison control help line. Please consult the doctor for further clarification. CONTACTS Phone : +919940472902 Email:millionhealthpharmaceuticals@gmail.com WEBSITE: https://millionpharma.sg