1 / 11

Tagrisso 80mg tablet Osimeritinib | Apple pharmaceuticals

Tagrisso 80mg (osimertinib) tablet is containing an active substance known as Osimeritinib, <br>which is formerly known as Mereletinib.Buy Tagrisso 80mg tablets @ Apple Pharmaceuticals <br>

Emimadi
Download Presentation

Tagrisso 80mg tablet Osimeritinib | Apple pharmaceuticals

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Tagrisso 80mg tablet | osimertinib80mg Apple pharmaceuticals

  2. A Tagrisso80mg tablet is containing an active substance known as Osimeritinib, which is formerly known as Mereletinib. • Tagrisso 80mg is considered as third generation medicine, which is available in tablet form.  • Tagrisso 80mg tablet is an inevitable, selectively deviated epidermal growth factor receptor prohibitor, containing anti-cancer activity.  Tagrisso 80mg tablet)

  3. A Tagrisso 80mg (osimertinib) tablet is widely indicated as first line therapy for advanced non-small cell lung cancer with EGFR mutation positive patients. • Tagrisso 80mg is also used for the treatment of patients affected with advanced EGFR T792M mutation positive NSCLC, disease has advanced on or after the tyrosine kinase inhibitor treatment. INDICATION

  4. The usual prescribed dosage of Tagrisso tablets are, 80mg tablet should be taken as a single dose . • Tagrisso 80mg tabletshould be administered with or without food. • If patient felt difficult to swallow the Tagrisso 80mg tablets as such, must disperse the tablet in 60ml of noncarbonated water and drink the solution immediately. • Tagrisso tablet do not break, crush or chew. DOSAGE

  5. Absorption: • Peak plasma concentration time of osimertinib reaches within 6 hours Distribution: * Volume of distribution 918L Plasma protein bound to Osimeritinib is 95% Metabolism : • The metabolism of Osimeritinib is occurs through oxidation. The Two pharmacologically active metabolite of Osimeritinib are AZ7550 & AZ5104 ADME

  6. Osimeritinib is similar in action when compared to other tyrosine kinase inhibitor drugs.  • Osimeritinib80mg is named tyrosine kinase inhibitor of epidermal development factor receptor which is available on the surface of tumor cells  • Osimeritinib is non-reversibly converge with mutant type of EGFR at 9 folds than wild sort  MECHANISM

  7. Some of the adverse effects occur during the therapy • Interstitial lung disease: To avoid this problem, withheld or discontinue the Tagrisso 80mg tablet. • QTc extension: Avoid concurrent use of Tagrisso 80mg with drug prolong the QTc • Cardiomyopathy: Periodic cardiac monitoring is assessed; in this condition discontinue the therap PRECAUTION

  8. Tagrisso 80mg tablet combines with strong CYP3A4 inducers causes reducing the exposure of Osimeritinib, this may leads to reduce the efficacy of Tagrisso. • Avoid the concomitant use of strong CYP3A4 inducers with Tagrisso 80mg tablets. • Tagrisso 80mg tablet combined with BCRP substrates may causes increasing the exposure of BCRP substrates. Thus results as increasing the adverse effects related to BCRP substrates  DRUG INTERACTION

  9. No contraindication occurred during the therapy • In some patient’s anaphylactic reaction may occur due to patients may contraindicated to the ingredient of the product • Tagrisso 80mg is a chemo medicine, in case of missed dose occurred skip the missed dose and follow the regular dosing schedule. CONTRAINDICATION

  10. Common side effects : • Fatigue; Lymphocytopenia (Low White Blood Cells); Low Sodium; Shortness of breath; Musculoskeletal Pain; Decreased Appetite; Cough Less common side effects : • Constipation; Increased serum creatinine; Colitis; Low potassium; Low magnesium; High calcium; Vomiting; Weakness; Diarrhea; High potassium; Low calcium; Swelling; Fever; Rash; Abdominal pain; Increased serum AST; Thrombocytopenia; Increased serum alkaline phosphatase; Chest pain; Weight loss.This are the tagrisso side effects. SIDE EFFECT

  11. phone No      :9987711567 • Email             :info@myapplepharma.com website • https://myapplepharma.com/osimeritinib-80mg.php Contact Us

More Related