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SOURCES OFDRUGS ANKITA TRIPATHI Department ofPharmacology IIMT COLLEGE OF PHARMACY, GREATER NOIDA
SOURCES OFDRUGS Drugs are obtained from six majorsources: Plantsources Syntheticsources Animalsources Microbiological sources Mineral/Earthsources Recombinant DNAtechnology IIMT COLLEGE OF PHARMACY
Plant Sources • Plant source is the oldest source of drugs. • Most of the drugs in ancient times were derived fromplants. • Almost all parts of the plants are used • i.e. leaves, stem, bark, fruits and roots. IIMT COLLEGE OF PHARMACY
Leaves IIMT COLLEGE OF PHARMACY
Flowers IIMT COLLEGE OF PHARMACY
Fruits IIMT COLLEGE OF PHARMACY
Seeds IIMT COLLEGE OF PHARMACY
Roots IIMT COLLEGE OF PHARMACY
Seeds IIMT COLLEGE OF PHARMACY
Bark IIMT COLLEGE OF PHARMACY
Animalsources • Byproducts of animals, including humans, are a source fordrugs • Replacementtherapy IIMT COLLEGE OF PHARMACY
Hormonal Replacement IIMT COLLEGE OF PHARMACY
Animalsource IIMT COLLEGE OF PHARMACY
MineralSources • Minerals are inorganic crystal substances that are found naturally on earth (or in thesoil). • Patients lacking an adequate level of these materials may take specific mineral based drugs to raise the level ofminerals. IIMT COLLEGE OF PHARMACY
MiscellaneousSources: IIMT COLLEGE OF PHARMACY
Metallic and Non-metallicsources: IIMT COLLEGE OF PHARMACY
SyntheticSources • A synthetic drug is produced using chemical synthesis, which rearranges chemical derivatives to form a newcompound. IIMT COLLEGE OF PHARMACY
SyntheticSources: IIMT COLLEGE OF PHARMACY
MicrobiologicalSources • Antibiotics are the chemical substances produces by a microorganism, which on high dilution can inhibit the growth and/or multiplication, or kill anothermicroorganism. Antibiotics IIMT COLLEGE OF PHARMACY
MicrobiologicalSources IIMT COLLEGE OF PHARMACY
Recombinant DNAtechnology • Recombinant DNA technology involves cleavage of DNA by enzyme restrictionendonucleases. • The desired gene is coupled to rapidly replicating DNA (viral, bacterial or plasmid). • The new genetic combination is inserted into the bacterial cultures which allow production of large amount of geneticmaterial. IIMT COLLEGE OF PHARMACY
Recombinant DNAtechnology • Forexample- • humaninsulin, • tissue plasminogenactivator, • hematopoietic growth factors likeerythropoietin • Advantages • Huge amounts of drugs can beproduced. • Drug can be obtained in pureform. • It is lessantigenic. IIMT COLLEGE OF PHARMACY
Assignment Enlist sources ofdrugs. Name any five plant sources ofdrugs Name any five mineral drugs with therapeuticuses Name any five synthetic drugs with therapeuticuses. IIMT COLLEGE OF PHARMACY
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