Febuxostat – A novel drug for treating hyperuricemia in gout-Pharmaffiliates Analytics and Synthetics Pvt. Ltd.

1. Febuxostat – A novel drug for treating hyperuricemia in gout- Pharmaffiliates Analytics and Synthetics Pvt. Ltd. Febuxostat is a recently approved medication used for the treatment of chronic gout and hyperuricemia. A non-purine, orally active selective inhibitor of xanthine oxidase, Febuxostat works by reducing the production of uric acid in the body. Gouty arthritis and hyperuricemia are the common diseases that have ailed humans for centuries. Febuxostat is effective in the treatment of mild-to-moderate renal/hepatic impairment with dramatic effects on the serum urate level. It can be safely used in patients with hypersensitivity reactions to allopurinol. With the rapid economic development, magnitude of diseases like gout have increases manifold times and there is an extensive need of medications like Febuxostat in the pharmaceutical world. Pharmaffiliates Analytics and Synthetics Pvt. Ltd., established in the 2005 is an eminent name worldwide as a leading manufacturer and supplier of active pharmaceutical ingredient (API), pharmaceutical impurity standard, pharmacopeial & non-pharmacopeial reference standards, drug gluconorides and metabolites, Isotope labelled reference standards, pesticides, Phytochemicals, agrochemicals and many more. Pharmaffiliates offers reference standard of Febuxostat and the impurities associated during the development stages of the drug. Details are listed below: Name of the product Product Code CAS No. PA 06 61000 FEBUXOSTAT (API) 144060-53-7 PA D 40640 1285539-74-3 Febuxostat D7 PA D 40630 1246819-50-0 Febuxostat D9 2-(3-CARBAMOYL-4- ISOBUTOXYPHENYL)-4- METHYLTHIAZOLE-5- CARBOXYLIC ACID 1239233-86-3 PA 06 61510 2-ISOBUTOXY-5-(4- METHYLTHIAZOL-2-YL) BENZONITRILE 1335202-60-2 PA 06 61520 2,2'-(4-ISOBUTOXY-1,3- PHENYLENE)BIS(4- METHYLTHIAZOLE-5- CARBOXYLIC ACID) 1330632-48-8 PA 06 61530 ETHYL 2-(3-CYANO-4- ISOBUTOXYPHENYL)-4- METHYLTHIAZOLE-5- CARBOXYLATE PA 06 61540 160844-75-7 ISOPROPYL 2-(3-CYANO-4- ISOBUTOXYPHENYL)-4- METHYLTHIAZOLE-5- PA 06 61550 1346238-10-5 1

2. Febuxostat – A novel drug for treating hyperuricemia in gout- Pharmaffiliates Analytics and Synthetics Pvt. Ltd. CARBOXYLATE 2-[4-(2- METHYLPROPOXY)PHENYL]-4- METHYLTHIAZOLE-5- CARBOXYLIC ACID PA 06 61560 1206550-99-3 FEBUXOSTAT ACYL-SS-D- GLUCURONIDE PA 06 61570 1351692-92-6 FEBUXOSTAT DIACID IMPURITY PA 06 61580 1239233-87-4 FEBUXOSTAT SEC-BUTOXY ACID PA 06 61590 1335202-59-9 FEBUXOSTAT TERT-BUTOXY ACID PA 06 61600 1530308-87-2 FEBUXOSTAT ISOPROPOXY ACID PA 06 61610 144060-52-6 3-CYANO-4- HYDROXYBENZOTHIOAMIDE PA 06 61620 NA FEBUXOSTAT DITHIOAMIDE IMPURITY PA 06 61630 1330632-46-6 FEBUXOSTAT DICYANO IMPURITY PA 06 61640 161718-81-6 FEBUXOSTAT DICYANO NITRO IMPURITY PA 06 61650 52054-41-8 3-DESCYANO-3- ((HYDROXYIMINO)METHYL) FEBUXOSTAT PA 06 61660 1350352-70-3 Order these impurities by simply clicking on the link given below: https://www.pharmaffiliates.com/send-enquiry Or visit our website www.pharmaffiliates.com The above-mentioned reference standards are supplied with a Certificate of Analysis, MSDS, and all the required documentation to ensure statutory domestic and international requirements. Our standards are of high purity and are scientifically characterized. 2