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Sumatriptan- An oldest drug in the Triptan class - Pharmaffiliates Analytics and Synthetics Pvt. Ltd.

A family of tryptamine-based drugs used in treating migraine and cluster headaches is termed as Triptans. Triptans exhibits agonist effect towards Serotonin 5 HT1Band 5 HT1D receptors in blood vessels hence causing their constriction.

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Sumatriptan- An oldest drug in the Triptan class - Pharmaffiliates Analytics and Synthetics Pvt. Ltd.

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  1. Sumatriptan- An oldest drug in the Triptan class - Pharmaffiliates Analytics and Synthetics Pvt. Ltd. A family of tryptamine-based drugs used in treating migraine and cluster headaches is termed as Triptans. Triptans exhibits agonist effect towards Serotonin 5-HT1Band 5-HT1D receptors in blood vessels hence causing their constriction. There are seven different types of Triptans available in the market. Sumatriptan is a selective agonist at serotonin 5-HT1-like receptors, including 5-HT1B/1D subtypes and is effective treatment for acute migraine attacks. The injectable form of Sumatriptan has also shown efficacy in the treatment of cluster headaches. Studies have revealed that migraine has become a highly disabling neurological condition for the individual as well as the society, healthcare services, and the economy. Sumatriptan which is an abortive medication for migraine attacks, belonging to the Triptan family is therefore an important drug in the Pharmaceutical parlance. Sumatriptan was introduced in 1991 and it is the oldest drug in the Triptan class. Another advantage with Sumatriptan is that it is the most flexible Triptan which is being available in subcutaneous injection, oral tablet, nasal spray, oral dispersible tablet and suppository forms. Pharmaffiliates Analytics and Synthetics Pvt. Ltd., which is a leading CRO present worldwide, offers Reference standard of Sumatriptan and the impurities associated with it formed during its drug development stages. Details of some of the standards are mentioned below: 1.Sumatriptan Product Code-PA 19 36000 CAS No- 103628-46-2 2.Sumatriptan Impurity D – An important degradation product of Sumatriptan. https://www.pharmaffiliates.com/ 1

  2. Sumatriptan- An oldest drug in the Triptan class - Pharmaffiliates Analytics and Synthetics Pvt. Ltd. Product Code- PA 19 36040 CAS No- 212069-94-8 3.Sumatriptan D6 Product Code- PA D 80640 CAS No- 1020764-38-8 For details on other impurities of Sumatriptan follow the link given below https://www.pharmaffiliates.com/impurities/10892/sumatriptan All the reference standards are provided by Pharmaffiliates in a pack size of 25 mg and 50 mg. The pack sizes can be customized as per the changing requirements. The Deuterium labeled standards are provided in pack sizes of 1mg and 10mg. A certificate of analysis along with NMR, MSDS, IR and all other required documentation to ensure statutory domestic and international requirements are provided along with the standard. Our standards are of high purity and are scientifically characterized. The laboratory and quality systems of Pharmaffiliates have successfully passed major second and third party audits which include NABL accreditation, ISO Guide 34 and USFDA. For more details visit our website www.pharmaffiliates.com https://www.pharmaffiliates.com/ 2

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