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Medicine at the Benchtop and the Bedside: Course Guidelines

Medicine at the Benchtop and the Bedside: Course Guidelines. Robert H. Chow, MD PhD USC-Caltech MD-PhD Program Keck School of Medicine. Medicine at the Benchtop and the Bedside. Seminar course for MD-PhD students Purpose: to introduce a clinical problem and research

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Medicine at the Benchtop and the Bedside: Course Guidelines

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  1. Medicine at the Benchtop and the Bedside: Course Guidelines Robert H. Chow, MD PhD USC-Caltech MD-PhD Program Keck School of Medicine

  2. Medicine at the Benchtop and the Bedside • Seminar course for MD-PhD students • Purpose: • to introduce a clinical problem and research related to that problem • to introduce the faculty and their research • to keep your mind active and curious during the first two years of med school! • Two students present • 2nd-yr student presents clinical problem • 1st-yr student presents research paper • One or two faculty mentors

  3. Tentative Outline Friday, September 25, 2009 Faculty facilitator: Dr. Robert Chow Student facilitator: none Friday, October 16, 2009 Faculty facilitator/s: Dr. James Weiland and Dr. Rajat Agrawal Student facilitators: TBA Friday, October 23, 2009 Faculty facilitator/s: Dr. Peter Jones and TBA Student facilitators: TBA Friday, October 30, 2009 Faculty facilitator/s: Dr. Ellis Meng and Dr. Uttam Sinha Student facilitators: TBA Friday, November 20, 2009 Faculty facilitator/s: Dr. Shelly Lu and TBA Student facilitators: TBA Friday, December 4, 2009 Faculty facilitator/s: Dr. Andrea Armani and Dr. Jane Emerson Student facilitators: TBA

  4. Following this slide are two sets of slides which can serve as templates for the student presentations • The mentor(s) may decide that an alternative format is preferable, in which case follow the mentors’ guidelines

  5. Template for Clinical Presentation For Medicine at the Benchtop and Bedside Robert H. Chow Zilkha Neurogenetic Institute

  6. History of • if there are juicy tidbits about the history of this clinical problem or the research…

  7. Case Presentation • Chief complaint • History of presenting illness • Physical Examination • Pertinent laboratory findings

  8. Clinical Presentation: Symptoms/Signs • What is difference between a symptom and a sign? • In detail, typical presenting symptoms and signs

  9. Diagnosis • Pathognomonic signs/symptoms • Lab tests • Possible springboard for the research part of this seminar

  10. Differential Diagnosis • Here, you list and discuss other diagnoses that should be considered for the presenting signs/symptoms

  11. Natural history • The clinical course of the disease/ illness when no treatment is given • Possible springboard for research portion of seminar

  12. Epidemiology • Characteristics at population level • Possible springboard for research portion of seminar

  13. Etiology/Pathogenesis • May review pertinent anatomy/ physiology here • Possible springboard for the research part of this seminar

  14. Therapy/Response • Current approach to therapy • Scientific basis of therapy (or lack thereof !) -- another springboard for the reseach part of the seminar

  15. Other interesting aspects of the clinical problem • Clinically relevant offshoots…

  16. Template for Research Paper Presentation For Medicine at the Benchtop and Bedside Robert H. Chow Zilkha Neurogenetic Institute

  17. Title of Article Authors (at least the first and last) Institutional Affiliation(s)

  18. Major Hypothesis or Question • Subhypothesis/ subquestion 1 • Subhypothesis/ subquestion 2 • Etc.

  19. Background • Short rationale or history of study of this hypothesis

  20. Preparation • Which animal/ tissue/ cell type used for the study • Any relevant details about the preparation, particularly justification for using this preparation

  21. Materials and Methods • Method(s) used to perform study • Approach to analysis

  22. Result 1 • Usually a figure clipped from paper

  23. Result 2 • Another figure… • It’s not necessary to review every figure in the paper, just the ones you want to focus on • Etc.

  24. Author’s Conclusions • Summarize what the authors state is the important conclusion(s) of the paper

  25. Critique of Paper • Similar to review of submitted manuscript or grant proposal • Evaluate the paper: • Author’s expertise • Validity of approach/ model/ methods • Quality of data • Validity of analysis • Validity of conclusions • Thoughts on how the study might have been improved -------------------------------------------------------------- • Ideas on how to follow up on the findings of the paper…

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