HeartSynergy0207

1. HeartSynergy0207

2. Overview • Why Fish Oil? • Fish Oil—a safe and natural source of DHA • The fetus is dependent on mother for DHA • Fish Oil supports a healthy pregnancy • Proven benefits • Why Nordic Naturals? • Unsurpassed purity and freshness • Natural triglyceride structure for enhanced absorption • Nordic Naturals is committed to environmental responsibilityand sustainability • Prenatal DHA/ProDHA • 450 mg DHA per serving • Small, easy to swallow 500 mg capsules • Third-party tested to be free of environmental contaminants

3. Why fish oil? • Omega-3 fats are not synthesized in the body and must be obtained through diet • Fish Oil is a safe and natural source of the Omega-3 fats, EPA and DHA • EPA and DHA are both important during pregnancy • However DHA is particularly important throughout pregnancy and during the early stages of life • DHA is a required nutrient for the proper development of the… • nervous system • brain • eyes • immune system J Perinat Med 2007;35::S19–24. Obstet Gynecol Surv 2004;59:722–30.

4. Why DHA? • The fetus is dependent on its mother for DHA intake • During the last trimester of pregnancy, there is a significant pull of DHA from the mother to the fetus to support the growth of the brain and nervous system • Mothers continue to provide DHA during the first stage of life via breast milk • A mother’s intake of DHA must be sufficient to maintain her own healthy levels and meet fetal demands, especially during the period of rapid nervous system development (last trimester–age 2)

5. Fish Oil supports a healthy pregnancy • The importance of DHA during pregnancy has been investigated for more than 30 years • Numerous studies have documented impaired nervous system and brain development in humans and laboratory animals fed no DHA • It has been proposed that dietary DHA played a significant role in the evolutionary expansion of the human brain Br J Nutr 2006;96:7–17. Biomed Environ Sci 2006;19:474–480. Pediatr Res 2005;58:741–748. Biol Psychiatry 2006;60:987–990.

6. Fish Oil supports a healthy pregnancy Research has shown that Fish Oil supplementation: • Improves DHA status of mothers, their breast milk, and infants Br J Nutr 1995;74:723–731, Eur J Clin Nutr 2004;58:429–443, Am J Clin Nutr 2003;77:226–233. Higher DHA status: • May help women to get pregnant Obstet Gynecol Surv 2004;59:722–30. • May lower the risk of premature births Exp Biol Med 2001;226:498–506, BJOG 2000;107:382–395. • Can reduce the risk of post-partum depression J Affect Disord 2002;69:15–29.

7. Fish Oil supports healthy children Research shows that getting enough DHA during pregnancy also… • Can improve behavior, attention, focus, and learning in children Child Dev 2004;75:1254–1267. • May improve intelligence in babies and children Pediatrics 2003;111:39–44. • May reduce the risk of allergies in infants J Allergy Clin Immunol 2003;112:1178–1184. • Can positively influence infant immune development Clin Exp Allergy 2004;34:1237–1242.

8. Fish Oil supports a child’s future • A Scandinavian study found that children born to mothers who had taken cod liver oil (2 tsp/day) during pregnancy and lactation had higher IQs than those born to mothers who had taken the corn oil placebo Pediatrics 2003;111:39-44. • Lower brain DHA levels are associated with cognitive deficits and increased behavioral indicators of anxiety, aggression, and depression in children Prostaglandins Leukot Essent Fatty Acids 2006;75:329–349.

9. Fish Oil supports healthy mothers • A woman’s demand for DHA increases significantly during pregnancy, and her reserves will remain low for 9–12 months after delivery unless her diet is supplemented • Shorter time between pregnancies increases the risk of developing DHA deficiency • Researchers have associated low levels of DHA with post-partum depression Seafood consumption, the DHA content of mothers' milk and prevalence rates of postpartum depression: a cross-national, ecological analysis. J Affect Disord. 2002;69:15–29.

10. How much DHA is required for a healthy pregnancy? • World’s leading experts on lipids conclude that during pregnancy and lactation women must ensure a minimum DHA intake of 300 mg daily Requirements for the essential omega-3 fats, EPA and DHA; ISSFAL 1999: National Institutes of Health. Washington DC. In the US, Dietary Reference Intakes (DRI) for DHA during pregnancy have not been established

11. DHA deficiency during pregnancy • The diet in industrialized nations is high in saturated, trans, and omega-6 fats • Foods rich in DHA (e.g., cold water fish) are less commonly consumed • The FDA and Environmental Protection Agency have advised women who may become pregnant, nursing mothers, and young children to avoid certain types of fish because of heavy metals and other environmental contaminants • Women are avoiding fish when they need DHA the most!

12. Are expecting mothers getting enough DHA? • National nutritional surveys have shown that the average intake of DHA during the last trimester of pregnancy is between zero and 100 mg J Lipid Res Mar 2005;46:516–525. • 90% of women surveyed were well below the minimum recommendation of 300 mg daily • Pregnant women in the United States reportedly have the third lowest intake of DHA in the world International Conference on Fatty Acids. Bethesda, MD;2004.

13. Is Fish Oil safer than fish? • Fish Oil is a safe and natural source of DHA ideal for pregnancy and nursing • High quality fish oil products are carefully processed to remove environmental contaminants such as heavy metals, PCBs, and Dioxins • Studies have concluded that Fish Oil may be a healthier source of DHA than fish because environmental toxins can be removed from fish oil Measurement of mercury levels in concentrated over-the-counter fish oil preparations: Is fish oil healthier than fish? Arch Pathol Lab Med 2003;127:1603–1605. Measurement of organochlorines in commercial over-the-counter fish oil preparations: Implications for dietary and therapeutic recommendations for omega-3 fatty acids and a review of the literature. Arch Pathol Lab Med 2005;129:74–77.

14. Prenatal DHA (DHA/ProDHA) • Provides essential nutrients, EPA and DHA • 450 mg of DHA per serving • Third-party tested with no detectable levels of heavy metals or other environmental contaminants • Small, easy to swallow soft gel caps • Absolutely pure and fresh with no fishy repeat

16. Quality matters • The primary concern with taking fish oil supplements is the quality of the supplement • Freshness • Purity • Source of raw material • Environmental responsibility • Taste • Good safety profile

17. Absorption—designed to digest triglycerides

18. The Nordic Naturals difference • Exclusive Raw Material • Cod Liver Oil: Only 100% Arctic Cod from Northern Norwegian waters • Fish Oil: Only anchovies and sardines—low on the food chain • Natural Triglyceride Form of Fish Oil • Triglyceride oil is the form of fat: • Naturally found in food, fish, and the human body • That our bodies are designed to efficiently digest • Naturally stabilized • In contrast, the ethyl ester form of fish oils, while accepted by the FDA, are considered synthetic and inferior oils in European countries—several countries will not allow these chemically modified oils to be sold as natural products or food supplements (2005 communications)

19. Commitment to a healthy environment Our planet is our most precious inheritance. At Nordic Naturals, we honor the richness of this gift through environmentally conscious practicesin the oceans, at our offices, and in our production facilities. In partnership with innovative individuals and organizations worldwide, we bring you the purest and freshest fish oils in the world, obtained through our environmentally responsible fishing practices.

20. Website dedicated to fish oil research www.omega-research.com Research abstracts Published reviews News Easy to navigate Free Resource for everyone

21. Thank You!Nordic Naturals Call: 800.662.2544 or visit: www.nordicnaturals.comDisclaimer: This information is provided by Nordic Naturals, Inc. for educational purposes only. Current and peer-reviewed research is cited. It is not intended as medical advice of any kind. The educational information in this document is not intended to diagnose, treat, or cure any disease, nor has this document been reviewed or approved by the FDA.