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What is a Phylogenetic Tree?. What is a phylogenetic tree used for?. A phylogenetic tree is used to help represent evolutionary relationships between organisms that are believed to have some common ancestry. The name “dendogram” is the broad term for trees.
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What is a phylogenetic tree used for? • A phylogenetic tree is used to help represent evolutionary relationships between organisms that are believed to have some common ancestry. • The name “dendogram” is the broad term for trees.
Where did the idea for a tree come from? • Charles Darwin is credited with the earliest representation of a phylogenetic tree published in his book The Origin of Species.
What does this tree look like? • There are many different ways to represent the information found in a phylogenetic tree. • The basic format of a tree is generally in one of the two forms shown, although there are other ways to represent the data.
What do the lines represent? • Each line on the tree represents one particular organism of interest. • The distance of the lines is used to determine how closely two organisms are related to one another or how long ago the may have had a common ancestor. • The line that connect all the other lines is the representation of the common ancestor that is being looked at to compare other organisms to.
The “Rooted” vs. “Unrooted” tree • A rooted tree is used to make inferences about the most common ancestor of the leaves or branches of the tree. Most commonly the root is referred to as an “outgroup”. • An unrooted tree is used to make an illustration about the leaves or branches, but not make assumption regarding a common ancestor.
The bifurcating tree • A tree that bifurcates has a maximum of 2 descendants arising from each of the interior nodes.
The multi-furcating tree • A tree that multi-furcates has multiple descendants arising from each of the interior nodes.
Where do I go to make a tree? • Many computational biology programs have dendogram programs. • An example of a free program that is available via the EMBL-EBI (European BioInformatics Institute) called ClutsalW or ClustalX. • You pick the program based on the format of your computer, i.e. command line verses graphical interface
What criteria is important when building a tree? • There are many different things that you should consider as you get set to build your tree. • Some examples are; • Efficiency • Power • Consistency/Reliability • Robustness • Are underlying assumptions ever violated
Limitations to the use of trees • It is important to remember that trees do have limitations. For example, trees are meant to provide insight into a research question and not intended to represent an entire species history. • Several factors, like gene transfers, may affect the output placed into a tree. • All knowledge of limitations related to DNA degradation over time must be considered, especially in the case of evolutionary trees aimed at ancient or extinct organisms.