Drugs acting on the gastrointestinal tract
Drugs used to inhibit or neutralise gastric secretion. . to reduce acid secretion and peptic ulceration (both duodenal and gastric), reflux, oesophagitis (in which gastric juice causes damage to the oesophagus) Reasons why peptic ulcers develop: - increased mucosal irritation , mucosal-damaging mechanisms enhanced acidity (acid, pepsin,stress, alcohol, cigarette smoking
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