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18 Nov. 2009. ANS.ppt. 2. Autonomic Nervous System. Functionally defined part of Peripheral Nervous System.Regulate visceral activity -- heart, blood vessels, digestive organs, urinary sys., most glands, parts of reproductive systems, etc.Mostly automatic, involuntary.. 18 Nov. 2009. ANS.ppt. 3. Autonomic Nervous System.
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1. 18 Nov. 2009 ANS.ppt 1 Autonomic Nervous System
2. 18 Nov. 2009 ANS.ppt 2
3. 18 Nov. 2009 ANS.ppt 3 Autonomic Nervous System
4. 18 Nov. 2009 ANS.ppt 4 Autonomic Nervous System Sympathetic Division
Parasympathetic Division
5. 18 Nov. 2009 ANS.ppt 5 Autonomic Nervous System Sympathetic Division
Parasympathetic Division
6. 18 Nov. 2009 ANS.ppt 6 Sympathetic Division Stress responses
Increased pulse & respiratory rate
Vasoconstriction to skin & viscera
Sweating (cold sweat)
Release of "adrenalin” (epinephrine)
Inhibition of digestive activity
Loss of appetite
7. 18 Nov. 2009 ANS.ppt 7 Parasympathetic Division Relaxation responses
Slower pulse & respiratory rate
Increased blood flow to skin & viscera
Increased digestive activity
SLUD
Salivation, Lacrimation, Urination, Digestion/Defecation
Increased reproductive interest, receptiveness
Penile erection, engorgement of vulva
8. 18 Nov. 2009 ANS.ppt 8 Autonomic Nervous System: Anatomy Two kinds of efferent neurons
Preganglionic neuron/axon
Cell body in CNS, axon to autonomic ganglion (usu. myelinated)
9. 18 Nov. 2009 ANS.ppt 9 Autonomic Nervous System: Anatomy Two kinds of efferent neurons
Ganglionic neuron
Cell body in ganglion, postganglionic axon to effector
(unmyelinated)
10. 18 Nov. 2009 ANS.ppt 10 Parasympathetic: Anatomy Ganglia
Terminal, = intramural ganglia
in walls of viscera, close to effector cells
Preganglionic axons relatively long
11. 18 Nov. 2009 ANS.ppt 11 Parasympathetic: Anatomy Connection of ANS to CNS
Craniosacral Division
preganglionic neurons from cranial nerves III, VII, IX,
preganglionic neurons from sacral spinal nerves S2-S4
12. 18 Nov. 2009 ANS.ppt 12 Parasympathetic: Anatomy Parasympathetic pathway
Hypothalamus & brain stem
Cranial or sacral outflow
Long preganglionic axon to intramural ganglion
Short ganglionic neuron (postganglionic axon)
13. 18 Nov. 2009 ANS.ppt 13 Sympathetic: Anatomy Ganglia
Sympathetic trunk = sympathetic chain ganglia
paired on either side of vertebrae
Prevertebral = collateral ganglia
unpaired among abdominal viscera
Celiac ganglion
Superior mesenteric ganglion
Inf. mesenteric ganglion
14. 18 Nov. 2009 ANS.ppt 14 Sympathetic: Anatomy Ganglia
Sympathetic trunk = sympathetic chain ganglia
paired on either side of vertebrae
Prevertebral = collateral ganglia
unpaired among abdominal viscera
Celiac ganglion
Superior mesenteric ganglion
Inf. mesenteric ganglion
15. 18 Nov. 2009 ANS.ppt 15 Sympathetic: Anatomy Connection of ANS to CNS
Sympathetic = Thoracolumbar Division
Preganglionic neurons from T1 - L2
Rami communicantes connect spinal nerves to sympathetic chain ganglia.
16. 18 Nov. 2009 ANS.ppt 16 Sympathetic: Anatomy Sympathetic pathway
Hypothalamus & brain stem
Spinal segment T1-L2
Preganglionic axon to ganglion
Synapse with ganglionic neuron
Postganglionic axon to effector.
17. 18 Nov. 2009 ANS.ppt 17 Sympathetic: Anatomy Adrenal medulla
One in each adrenal gland
Develops as “misplaced” sympathetic ganglion
Neuron-like cells without axons
Secrete epinephrine, norepinephrine
18. 18 Nov. 2009 ANS.ppt 18 “Dual Innervation” Most organs innervated by both sympathetic and parasympathetic divisions (Table 14.4).
Sympathetic only:
Adrenal medulla, sweat glands, arrector pili, kidney, liver (by epinephrine)
Arteries (constriction of most, dilation in skeletal muscles)
Parasympathetic only:
Ciliary muscle of eye contracts for near vision
Penis/clitoris erection; vaginal lubrication
19. 18 Nov. 2009 ANS.ppt 19 Autonomic neurotransmitters Parasympathetic
Preganglionic axons
ACh
Postganglionic axons
ACh
All “cholinergic” Sympathetic
Preganglionic axons
ACh (“cholinergic”)
Postganglionic axons
norepinephrine (NE)
“adrenergic”
20. 18 Nov. 2009 ANS.ppt 20 Cholinergic (ACh) receptors Nicotinic receptors (excitatory)
Somatic neuromuscular junctions
Parasympathetic ganglionic dendrites (in ganglia)
Sympathetic ganglionic dendrites (in ganglia)
Adrenal medulla cells
21. 18 Nov. 2009 ANS.ppt 21 Cholinergic (ACh) receptors Muscarinic (excitatory or inhibitory)
Parasympathetic effectors
Smooth muscle cells
Cardiac muscle cells; inhibition of cardiac muscle
Slows heartbeat
22. 18 Nov. 2009 ANS.ppt 22 Adrenergic receptors All Sympathetic
Alpha receptors bind specifically to Norepinephrine (NE)
pupil dilation
constriction of some arterioles
constriction of renal arteries ? decreased urine production
contraction of spleen ? more blood into circulation
23. 18 Nov. 2009 ANS.ppt 23 Adrenergic receptors Beta receptors bind specifically to Epinephrine (E)
constrict salivary gland arterioles ? decrease salivation
liver cells, glycogen ? glucose in blood
adipocytes, stored fat ? glycerol & fatty acids in blood
increase heart rate & force of contraction
dilate arteries to skeletal muscle, constrict others
decrease GI tract activity
relax urinary bladder wall
24. 18 Nov. 2009 ANS.ppt 24 ANS Interactions:A day in a life Sympathetic
Commuting, traffic
Pop quiz
Late for appointment
Caught in rain shower
Soaked!! Cold!
1st date: I like him, does he like me?
Parasympathetic
Second cup of coffee
Bathroom
Lunch with friends
Home, warm shower
Great dinner! Mmmm.
Good night kiss!! He likes me!