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Eltrombopag is a medication that has been developed for certain conditions that lead to thrombocytopenia. It is a small molecule agonist of the c-mpl receptor, which is the physiological target of the hormone thrombopoietin.
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ELTROMBOPAG Eltrombopagis a medication that has been developed for certain conditions that lead to thrombocytopenia.
DESCRIPTION • INDICATION Eltrombopag is a prescription drug which is used under the guidance of the doctor. Eltrombopagdrug may be used as part of a combination therapy. Thereby drug may need to take it with other medications. • Eltrombopag is mainly indicated for the treatment of patients having : • Reduced platelet levels due to chronic immune thrombocytopenia • Reduced platelet counts due to chronic hepatitis C virus infection • Severe aplastic Anemia : • First line treatment of severe aplastic Anemia • Treatment of refractory severe aplastic Anemia
MECHANISM Eltrombopag be part of class of drugs called thrombopoietin (TPO) receptor agonists. A classification of drugs is aassociation of medications which work in a similar way. These drugs are often used to treat similar conditions. Eltrombopag works by raise cells in bone marrow andleads these cells to make various platelets. This effect reducesthe risk of bleeding. • PRECAUTION • The drug causes warning condition, call the doctor while new medication interaction Disease progression warning: Avoid using the drug while the patients have myelodysplastic syndrome (MDS), will increases the risk of death.
Common side effects: Low red blood cells, nausea, fever, weakness, pain in head, cough Serious side effects: • Urine in dark color, • Yellowing of your skin, • Abdomen swelling, • Confusion, • Chest pain, • Dyspnea
PREGNANCY & LACTATION Pregnancy category is C Use the Eltrombopag with caution if asset outweigh risks. Animal studies reveal risk and human studies not available or neither animal nor human studies done. The presence of Eltrombopag or metabolites in human milk, the drug has possible serious side effects for breastfed child. The drug is not recommended during breast feeding. • STORAGE CONDITION • Store at room temperature 20° and 25°. • Discard the left-out medicine if not used within 30 minutes
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