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Evergraf 0.25mg consist of an active ingredient known as Everolimus which intrudes with the growth of cancer cell and the process is slowed down, this tablet is not a curable medication, which helps to slow their spreading into the body
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APPLE PHARMACEUTICALS We will not dispense any prescription medication without a valid prescription from a licensed physician
EVEROLIMUS Evergraf 0.25mg Tablets
DESCRIPTION INDICATION • Primarily Evergraf 0.25mg tablets indicated for the treatment : • * kidney carcinoma • * Breast carcinoma • * Brain carcinoma • Everolimus is also indicated in various advanced stage cancer in stomach, intestines or pancreas. Evergraf 0.25mg consist of an active ingredient known as Everolimus which is intrude with growth of cancer cell and process is slows down. Evergraf 0.25mg tablets is not a curable medication, which is helps to slow their spreading in to the body.
MECHANISM DOSAGE • Evergraf 0.25mg tablets should be given with or without food. • Dosage regimen of Evergraf 0.25mg; • In breast cancer, renal cell cancer, pancreatic cancer, Neuro endocrine cancer: • The prescribed dosage is 10mg should be taken as a single dose. • In Brain or intracranial cancer: • The prescribed dosage of Evergraf as a single dose. is 4.5mg/m2 given orally • In pediatric: • The pediatric dosage of Evergraf as a single dose in brain or intracranial tumor is 4.5mg/m2 should be given orally. Everolimus is an inhibitor of mTOR, joins at high compatibility to FK506 binding protein 12, via producing drug complex that inhibits the productive of mTOR. This inhibition reduces the activity of effectors downstream, which may lead to stoppage of cell progression from G1 into S phase, finally causes cell growth arrest and apoptosis
PREGNANCY AND LACTATION STORAGE • Evergraf 0.25mg tablet store at 25°C • Store the medicine away from moisture, heat and light Pregnancy category of Everolimus C In patients Evergraf 0.25mg is used only after knowing the benefits to the mother exceed the risk to fetus. Breast feeding should not be suggested MISSED DOSE • In case of missed dose, patients must consult with medical practitioner and follow the instructions given by them. Thereby missed dose should be avoid and follow the regular dosing schedule.
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