Forzest Tablets (Generic Tadalafil Tablets)

1. Forzest Tablets (Generic Tadalafil Tablets) © The Swiss Pharmacy

2. Forzest Tablets (Generic Tadalafil Tablets) Forzest (Generic Tadalafil Tablets) is used to treat erectile dysfunction, also known as impotence, in adult men. This is when a man cannot get, or maintain, a hard erect penis suitable for sexual activity. In order for tadalafil to be effective for the treatment of erectile dysfunction, sexual stimulation is required. Forzest is also used to treat urinary symptoms associated with a common condition called benign prostatic hyperplasia. © The Swiss Pharmacy

3. Forzest Tablets (Generic Tadalafil Tablets) Forzest Tablets are manufactured by Hetero Labs Ltd. and marketed by Sun Pharmaceutical Industries Limited, India. They are available in the strength of 20 mg. © The Swiss Pharmacy

4. Forzest Tablets (Generic Tadalafil Tablets) Chemical Structure © The Swiss Pharmacy

5. Forzest Tablets (Generic Tadalafil Tablets) The active ingredient contained in Forzest tablets is Tadalafil. Each film-coated Forzest tablet contains 20 mg of Tadalafil. © The Swiss Pharmacy

6. Forzest Tablets (Generic Tadalafil Tablets) Uses of Forzest 20mg Tablets: Forzest (Generic Tadalafil Tablets) is used to treat men who have erectile dysfunction (also called sexual impotence). Tadalafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection. By controlling the enzyme, Forzest helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. Tadalafil is also used to treat men who have signs and symptoms of benign prostatic hyperplasia (BPH). URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

7. Forzest Tablets (Generic Tadalafil Tablets) Uses of Forzest 20mg Tablets: BPH is caused by an enlarged prostate. Men with BPH usually have difficulty urinating, a decreased flow of urination, hesitation at the beginning of urination, and a need to get up at night to urinate. Tadalafil (Forzest Tablets) is also used in both men and women to treat the symptoms of pulmonary arterial hypertension to improve your ability to exercise. This is high blood pressure that occurs in the main artery that carries blood from the right side of the heart (the ventricle) to the lungs. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

8. Forzest Tablets (Generic Tadalafil Tablets) Recommended Adult Dosage Erectile Dysfunction (ED): Erectile Dysfunction (ED): For most patients, the recommended starting dose of Forzest Tablets Tadalafil Tablets) for use as needed is 10 mg taken prior to anticipated sexual activity and with or without food. Increase to 20 mg or decrease to 5 mg based upon efficacy / tolerability. Improves erectile function compared to placebo up to 36 hours post dose. Not to be taken more than once per day. i.e. 24 hours must pass before you take your next dose. Forzest Tablets (Generic URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

9. Forzest Tablets (Generic Tadalafil Tablets) Recommended Adult Dosage Tadalafil Tablets for once daily use: Tadalafil Tablets for once daily use: Erectile Dysfunction (ED): 2.5 mg taken once daily, without regard to timing of sexual activity. May increase to 5 mg based upon efficacy and tolerability. BPH: BPH: 5 mg, taken at approximately the same time every day ED and BPH: 5 mg, taken at approximately the same time every day URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

10. Forzest Tablets (Generic Tadalafil Tablets) Recommended Adult Dosage Pulmonary Arterial Hypertension (PAH): Pulmonary Arterial Hypertension (PAH): The recommended dose of Tadalafil tablets (Forzest) is 40 mg (two 20 mg tablets) taken once daily with or without food. Dividing the dose (40 mg) over the course of the day is not recommended. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

11. Forzest Tablets (Generic Tadalafil Tablets) Contraindications ➔Forzest is contraindicated in patients with a known hypersensitivity to Tadalafil or any component of the tablet. ➔Administration of Forzest (Generic Tadalafil Tablets) to patients using any form of organic nitrate is contraindicated. Forzest was shown to potentiate the hypotensive effect of nitrates ➔Administration of this medicine with guanylate cyclase (GC) stimulators, such as Riociguat is also contraindicated. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

12. Forzest Tablets (Generic Tadalafil Tablets) Contraindications The following groups of patients with cardiovascular disease were not included in clinical trials and the use of Tadalafil (Forzest tablets) is therefore contraindicated: ➔Patients with myocardial infarction within the last 90 days ➔Patients with unstable angina or angina occurring during sexual intercourse ➔Patients with New York Heart Association Class 2 or greater heart failure in the last 6 months ➔Patients with uncontrolled arrhythmias, hypotension (less than 90/50 mm Hg), or uncontrolled hypertension ➔Patients with a stroke within the last 6 months. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

13. Forzest Tablets (Generic Tadalafil Tablets) Contraindications ➔Forzest tablets are contraindicated in patients who have loss of vision in one eye because of non-arteritic anterior ischaemic optic neuropathy (NAION), regardless of whether this episode was in connection or not with previous PDE5 inhibitor exposure. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

14. Forzest Tablets (Generic Tadalafil Tablets) Storage Instructions Forzest Tablets (Generic Tadalafil Tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

15. Forzest Tablets (Generic Tadalafil Tablets) Warnings Patients should not use Forzest tablets if sex is inadvisable due to cardiovascular status. Use of Forzest with alpha-blockers, antihypertensives or substantial amounts of alcohol (5 units or more) may lead to hypotension. Forzest is not recommended in combination with alpha-blockers for the treatment of BPH because efficacy of the combination has not been adequately studied and because of the risk of blood pressure lowering. Caution is advised when Forzest is used as a treatment for ED in men taking alpha-blockers. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

16. Forzest Tablets (Generic Tadalafil Tablets) Warnings Patients should seek emergency treatment if an erection lasts for more than 4 hours. Use Forzest with caution in patients predisposed to priapism. Patients should stop Forzest (Generic Tadalafil Tablets) and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non-arteritic anterior ischemic optic neuropathy (NAION). URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

17. Forzest Tablets (Generic Tadalafil Tablets) Warnings Forzest tablets should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a “crowded” optic disc may also be at an increased risk of NAION. Patients should stop Forzest tablets and seek prompt medical attention in the event of sudden decrease or loss of hearing Prior to initiating treatment with Forzest for BPH, consideration should be given to other urological conditions that may cause similar symptoms. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

18. Forzest Tablets (Generic Tadalafil Tablets) Driving or Operating Machinery Tadalafil (Forzest tablets) may make you feel dizzy or affect your vision and so may affect your ability to drive or operate machinery safely. Don't drive or operate machinery until you know how this medicine affects you and you are sure it won't affect your performance. It's best to avoid drinking too much alcohol if you're taking Tadalafil. Drinking alcohol can reduce your ability to get an erection and so might make the Tadalafil less effective. As Tadalafil can also make some people feel dizzy or lightheaded, this could be made worse if you drink alcohol. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

19. Forzest Tablets (Generic Tadalafil Tablets) Possible Side Effects Most common Forzest (Generic Tadalafil Tablets) side effects with an incidence rate of greater than or equal to 2% include headache, dyspepsia, back pain, myalgia, nasal congestion, flushing, and pain in limb. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

20. Forzest Tablets (Generic Tadalafil Tablets) Possible Side Effects The following side effects occurred in less than 2% of the patients during Tadalafil clinical trials: Body as a Whole — asthenia, face edema, fatigue, pain Cardiovascular — angina pectoris, chest pain, hypotension, myocardial infarction, postural hypotension, palpitations, syncope, tachycardia Digestive — abnormal liver function tests, dry mouth, dysphagia, esophagitis, gastritis, GGTP increased, loose stools, nausea, upper abdominal pain, vomiting, gastroesophageal reflux disease, hemorrhoidal hemorrhage, rectal hemorrhage Musculoskeletal — arthralgia, neck pain Nervous — dizziness, hypesthesia, insomnia, paresthesia, somnolence, vertigo URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

21. Forzest Tablets (Generic Tadalafil Tablets) Possible Side Effects The following side effects occurred in less than 2% of the patients during Tadalafil clinical trials: Renal and Urinary — renal impairment Respiratory — dyspnea, epistaxis, pharyngitis Skin and Appendages — pruritus, rash, sweating Ophthalmologic — blurred vision, changes in color vision, conjunctivitis (including conjunctival hyperemia), eye pain, lacrimation increase, swelling of eyelids Otologic — sudden decrease or loss of hearing, tinnitus Urogenital — erection increased, spontaneous penile erection URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

22. Forzest Tablets (Generic Tadalafil Tablets) Forzest Tablets Overdosage Single doses up to 500 mg have been given to healthy subjects, and multiple daily doses up to 100 mg have been given to patients. Adverse events observed were similar to those seen at lower doses. In cases of Forzest overdose, standard supportive measures should be adopted as required. Hemodialysis contributes negligibly to Tadalafil elimination. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

23. Forzest Tablets (Generic Tadalafil Tablets) Forzest Tablets During Pregnancy Tadalafil (Forzest Tablets) has been classified by the US FDA as Pregnancy Category B. Tadalafil tablets are not indicated for use in Women. There are no data regarding the use of Tadalafil tablets in pregnant women to inform any drug-associated risks for adverse developmental outcomes. During animal reproduction studies, no adverse developmental effects were observed with oral administration of Tadalafil to pregnant rats or mice during organogenesis at exposures up to 11 times the maximum recommended human dose (MRHD) of 20mg/day. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy

24. Forzest Tablets (Generic Tadalafil Tablets) Forzest Tablets Forzest Tablets (Generic Tadalafil Tablets) are manufactured by Hetero Labs and marketed by Sun Pharmaceutical Industries, India. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9558_Forzest-Tablets.html © The Swiss Pharmacy