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Pari Tablets (Generic Paroxetine Hydrochloride Tablets)

Pari (Generic Paroxetine Hydrochloride Tablets) is a selective serotonin reuptake inhibitor (SSRI) used in adults to treat mental health conditions like depression, anxiety, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder (PD), Generalised Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Post-Traumatic Stress Disorder (PTSD) and Premenstrual Dysphoric Disorder (PMDD).

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Pari Tablets (Generic Paroxetine Hydrochloride Tablets)

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  1. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) © The Swiss Pharmacy

  2. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Pari (Generic Paroxetine Hydrochloride Tablets) is a selective serotonin reuptake inhibitor (SSRI) used in adults to treat mental health conditions like depression, anxiety, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder (PD), Generalised Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Post-Traumatic Stress Disorder (PTSD) and Premenstrual Dysphoric Disorder (PMDD). © The Swiss Pharmacy

  3. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Pari Tablets are manufactured by IPCA Laboratories Limited, India in the strength of 10 mg, 20 mg, 30 mg and 40 mg. © The Swiss Pharmacy

  4. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Chemical Structure © The Swiss Pharmacy

  5. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) The active ingredient contained in Pari tablets is Paroxetine Hydrochloride. Each film-coated Pari tablet contains Paroxetine Hydrochloride equivalent to 10 mg, 20 mg, 30 mg or 40 mg of Paroxetine. © The Swiss Pharmacy

  6. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Uses of Pari 10 mg, 20 mg, 30 mg and 40 mg Tablets: Pari (Generic Paroxetine tablets) is a type of antidepressant known as an SSRI (selective serotonin reuptake inhibitor). Pari (Generic Paroxetine Hydrochloride Tablets) is used to treat depression, obsessive-compulsive disorder (OCD), panic disorder, generalized anxiety disorder (GAD), social anxiety disorder (also known as social phobia), premenstrual dysphoric disorder (PMDD), and posttraumatic stress disorder (PTSD). Paroxetine belongs to a group of medicines known as selective serotonin reuptake inhibitors (SSRIs). These medicines are thought to work by increasing the activity of the chemical called serotonin in the brain. Paroxetine helps many people recover from depression, and it has fewer unwanted effects than older antidepressants. It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  7. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Uses of Pari 10 mg, 20 mg, 30 mg and 40 mg Tablets: This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  8. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Recommended Adult Dosage Major Depressive Disorder: Major Depressive Disorder: For most patients, the starting dose of Pari Tablets Pari Tablets (Generic Paroxetine Tablets) is 20 mg/day to be administered as a single daily dose with or without food, usually in the morning. Some patients not responding to a 20 mg dose may benefit from dose increases, in 10 mg/day increments, up to a maximum of 50 mg/day. Obsessive Compulsive Disorder: Obsessive Compulsive Disorder: The recommended dose of Paroxetine Hydrochloride tablets in the treatment of OCD is 40 mg daily administered as a single daily dose with or without food, usually in the morning. Patients should be started on 20 mg/day and the dose can be increased in 10 mg/day increments. Dose changes should occur at intervals of at least 1 week. Patients were dosed in a range of 20 to 60 mg/day in the clinical trials. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  9. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Recommended Adult Dosage Panic Disorder: Panic Disorder: The recommended starting dose of Paroxetine Hydrochloride tablets (Pari) in the treatment of panic disorder is 10 mg/day administered as a single daily dose with or without food, usually in the morning. The target dose of Paroxetine tablets in the treatment of panic disorder is 40 mg/day. Dose changes should occur in 10 mg/day increments and at intervals of at least 1 week. Patients were dosed in a range of 10 to 60 mg/day in the clinical trials. The maximum dosage should not exceed 60 mg/day. Social Anxiety Disorder: Social Anxiety Disorder: The recommended starting dose of Paroxetine Hydrochloride tablets (Pari) in the treatment of social anxiety disorder is 20 mg/day administered as a single daily dose with or without food, usually in the morning. Available information does not suggest any additional benefit for doses above 20 mg/day. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  10. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Recommended Adult Dosage Generalized Anxiety Disorder: Generalized Anxiety Disorder: The recommended starting dose of Paroxetine Hydrochloride tablets (Pari) in the treatment of generalized anxiety disorder is 20 mg/day administered as a single daily dose with or without food, usually in the morning. There is no sufficient evidence to suggest a greater benefit to doses higher than 20 mg/day. Posttraumatic Stress Disorder: Posttraumatic Stress Disorder: The recommended starting dose of Paroxetine Hydrochloride tablets (Pari) in the treatment of posttraumatic stress disorder is 20 mg/day administered as a single daily dose with or without food, usually in the morning. There was no sufficient evidence in a fixed dose study, to suggest a greater benefit for a dose of 40 mg/day compared to 20 mg/day. Dose changes, if indicated, should occur in 10 mg/day increments and at intervals of at least 1 week. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  11. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Recommended Adult Dosage Premenstrual Dysphoric Disorder: Premenstrual Dysphoric Disorder: The recommended starting dose of Pari (Generic Paroxetine Hydrochloride Tablets) in the treatment of premenstrual dysphoric disorder is 12.5 mg/day administered as a single daily dose with or without food, usually in the morning. Pari may be administered either daily throughout the menstrual cycle or limited to the luteal phase of the menstrual cycle, depending on physician assessment. The recommended initial dose is 12.5 mg/day. During clinical trials, both 12.5 mg/day and 25 mg/day were shown to be effective. Dose changes should occur at intervals of at least 1 week. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  12. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Contraindications ➔Pari tablets are contraindicated in patients with a known hypersensitivity to Paroxetine Hydrochloride or any component of the tablet. ➔The use of MAOIs intended to treat psychiatric disorders with Pari (Paroxetine Hydrochloride Tablets) or within 14 days of stopping treatment with Paroxetine tablets is contraindicated because of an increased risk of serotonin syndrome. The use of Paroxetine tablets within 14 days of stopping an MAOI intended to treat psychiatric disorders is also contraindicated. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  13. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Contraindications ➔Starting Paroxetine tablets in a patient who is being treated with MAOIs such as Linezolid or intravenous methylene blue is also contraindicated because of an increased risk of serotonin syndrome. ➔Concomitant use in patients taking Pimozide or Thioridazine is contraindicated. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  14. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Storage Instructions Pari Tablets (Generic Paroxetine Hydrochloride Tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  15. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Warnings Increased risk of suicidal thoughts and behavior in pediatric and young adult patients taking antidepressants. Closely monitor all antidepressant-treated patients for clinical worsening and emergence of suicidal thoughts and behaviors. Pari is not approved for use in pediatric patients. Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents (e.g., SSRI, SNRI, triptans), but also when taken alone. If occurs, discontinue Pari (Generic Paroxetine Hydrochloride Tablets) and initiate supportive measures. Embryofetal and Neonatal Toxicity: Can cause fetal and neonatal harm. Increased risk of cardiovascular malformations for exposure during the first trimester. Exposure in late pregnancy may lead to an increased risk for persistent pulmonary hypertension (PPNH) of the newborn. © The Swiss Pharmacy

  16. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Warnings Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs, other antiplatelet drugs, warfarin, and other anticoagulant drugs may increase risk. Activation of Mania/Hypomania: Screen patients for bipolar disorder. Seizures: Use with caution in patients with seizure disorders. Angle-Closure Glaucoma: Angle-closure glaucoma has occurred in patients with untreated anatomically narrow angles treated with antidepressants. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  17. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Possible Side Effects Most common Pari (Paroxetine Hydrochloride Tablets) side effects with an incidence rate of greater than or equal to 5% and at least twice placebo in placebo-controlled MDD, PD, SAD, and PMDD clinical trials: abnormal ejaculation, abnormal vision, asthenia, constipation, decreasedappetite, diarrhea, dizziness, dry mouth, female genital disorder, impotence, insomnia, libido decreased, nausea, somnolence, sweating, tremor. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  18. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Pari Tablets Overdosage Commonly reported adverse events associated with Paroxetine Hydrochloride (Pari tablets) overdosage include somnolence, coma, nausea, tremor, tachycardia, confusion, vomiting, and dizziness. Other notable signs and symptoms observed with overdoses involving paroxetine (alone or with other substances) include mydriasis, convulsions (including status epilepticus), ventricular dysrhythmias (including torsades de pointes), hypertension, aggressive reactions, syncope, hypotension, stupor, bradycardia, dystonia, rhabdomyolysis, symptoms of hepatic dysfunction (including hepatic failure, hepatic necrosis, jaundice, hepatitis, and hepatic steatosis), serotonin syndrome, manic reactions, myoclonus, acute renal failure, and urinary retention. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  19. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Treatment of Pari Tablets Overdosage No specific antidotes for Paroxetine Hydrochloride (Pari Tablets) are known. Treatment should consist of those general measures employed in the management of overdosage with any drugs effective in the treatment of major depressive disorder. Ensure an adequate airway, oxygenation, and ventilation. Monitor cardiac rhythm and vital signs. General supportive and symptomatic measures are also recommended. Induction of emesis is not recommended. Due to the large volume of distribution of this drug, forced diuresis, dialysis, hemoperfusion, or exchange transfusion are unlikely to be of benefit. A specific caution involves patients who are taking or have recently taken Paroxetine who might ingest excessive quantities of a tricyclic antidepressant. In such a case, accumulation of the parent tricyclic and/or an active metabolite may increase the possibility of clinically significant sequelae and extend the time needed for close medical observation. In managing overdosage, consider the possibility of multiple drug involvement. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  20. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Pari Tablets During Pregnancy Paroxetine Hydrochloride (Pari Tablets) has been classified by the US FDA as Pregnancy Category D. Epidemiological studies have shown that infants exposed to Paroxetine Hydrochloride in the first trimester of pregnancy have an increased risk of congenital malformations, particularly cardiovascular malformations. In case Paroxetine Hydrochloride (Pari Tablets) is used during pregnancy, or if the patient becomes pregnant while taking Paroxetine, advise the patient of the potential hazard to the fetus. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

  21. Pari Tablets (Generic Paroxetine Hydrochloride Tablets) Pari Tablets Pari Tablets (Generic Paroxetine Hydrochloride Tablets) are manufactured by IPCA Laboratories Limited, India. URL: URL: https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html https://www.theswisspharmacy.com/product_info.php?info=p9722_Pari-Tablets.html © The Swiss Pharmacy

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