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The 10 Most Advanced Medical Imaging Solution Providers 2023

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The 10 Most Advanced Medical Imaging Solution Providers 2023

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  1. MAY | ISSUE : 02 | 2023 Pg.No: 24 Global Exploration Naviga?ng the Complex World of Medical Imaging Pg.No: 32 DR. MAX AHNEN Demystifying Advancements COO and Co-founder POSITRIGO Understanding the Technology and Applica?ons of Advanced Imaging JANNIS FISCHER CEO and Co-founder POSITRIGO Enriching the Global Healthcare with Precise Imaging Solutions

  2. Positrigo’s vision is to ‘imaging everyone,’ which means that it wants to broaden the availability of func?onal imaging and to allow a wide range of pa?ents with brain-related disorders the access to precision imaging.

  3. Positrigo’s vision is to ‘imaging everyone,’ which means that it wants to broaden the availability of func?onal imaging and to allow a wide range of pa?ents with brain-related disorders the access to precision imaging.

  4. This interoperability enhances communication and n the fast-paced world of healthcare, advanced collaboration between healthcare providers, facilitating medical imaging has become an indispensable tool better patient care and improved outcomes. for accurate diagnosis and treatment planning. As Editor’s technology continues to evolve, so does the need As we navigate the complex landscape of advanced medical I for innovative and reliable medical imaging imaging, it is essential to recognize and acknowledge the solution providers. These companies play a crucial role in Note contributions of these solution providers. Their dedication equipping healthcare facilities with state-of-the-art imaging to innovation, customer support, and data integration is equipment, software, and support services that enable instrumental in advancing the field of medical imaging and healthcare professionals to deliver optimal patient care. revolutionizing healthcare. By partnering with the right medical imaging solution provider, healthcare facilities can The realm of advanced medical imaging encompasses a stay at the forefront of technology, providing the highest wide range of modalities, including magnetic resonance Global Facilitation standard of care to their patients. imaging, computed tomography, positron emission tomography, and ultrasound. Each modality has its unique with Contemporary advantages and applications, catering to the diverse needs Through the latest edition – The 10 Most Advanced of different medical specialties. As such, medical imaging Medical Imaging Solution Providers 2023 of The CIO solution providers must offer a comprehensive portfolio of World, we delve into the world of advanced medical Emulations imaging systems, ensuring they can meet the specific imaging solution providers, exploring their role, requirements of healthcare providers across various innovations, and impact on healthcare delivery. We disciplines. highlight the importance of choosing the right partner in advancing medical imaging capabilities and achieving CIO In today’s interconnected world, interoperability and data excellence in patient care. integration are paramount. Leading medical imaging solutions providers offer solutions that seamlessly integrate with hospital information systems and electronic medical records, allowing for efficient data management and streamlined workflows. - Prh D. Bombarde

  5. This interoperability enhances communication and n the fast-paced world of healthcare, advanced collaboration between healthcare providers, facilitating medical imaging has become an indispensable tool better patient care and improved outcomes. for accurate diagnosis and treatment planning. As Editor’s technology continues to evolve, so does the need As we navigate the complex landscape of advanced medical I for innovative and reliable medical imaging imaging, it is essential to recognize and acknowledge the solution providers. These companies play a crucial role in Note contributions of these solution providers. Their dedication equipping healthcare facilities with state-of-the-art imaging to innovation, customer support, and data integration is equipment, software, and support services that enable instrumental in advancing the field of medical imaging and healthcare professionals to deliver optimal patient care. revolutionizing healthcare. By partnering with the right medical imaging solution provider, healthcare facilities can The realm of advanced medical imaging encompasses a stay at the forefront of technology, providing the highest wide range of modalities, including magnetic resonance Global Facilitation standard of care to their patients. imaging, computed tomography, positron emission tomography, and ultrasound. Each modality has its unique with Contemporary advantages and applications, catering to the diverse needs Through the latest edition – The 10 Most Advanced of different medical specialties. As such, medical imaging Medical Imaging Solution Providers 2023 of The CIO solution providers must offer a comprehensive portfolio of World, we delve into the world of advanced medical Emulations imaging systems, ensuring they can meet the specific imaging solution providers, exploring their role, requirements of healthcare providers across various innovations, and impact on healthcare delivery. We disciplines. highlight the importance of choosing the right partner in advancing medical imaging capabilities and achieving CIO In today’s interconnected world, interoperability and data excellence in patient care. integration are paramount. Leading medical imaging solutions providers offer solutions that seamlessly integrate with hospital information systems and electronic medical records, allowing for efficient data management and streamlined workflows. - Prh D. Bombarde

  6. 08 Enriching the Global Healthcare with Precise Imaging Solutions Medical Imaging Encord Stringing a Powerful Cord of Futuris?c Consultancy Data-Centric Computer Vision Flourishing Healthcare with Exquisite Solu?ons 28 20 24 Global Exploration Mirada C O V E R 36 Naviga?ng the Complex World of Medical Imaging Medical S T O R Y An Anecdote of Health, Demystifying Advancements Hope, and Healing! JANNIS FISCHER Understanding the DR. MAX AHNEN CEO and Co-founder Technology and Applica?ons COO and Co-founder POSITRIGO of Advanced Imaging POSITRIGO 32

  7. 08 Enriching the Global Healthcare with Precise Imaging Solutions Medical Imaging Encord Stringing a Powerful Cord of Futuris?c Consultancy Data-Centric Computer Vision Flourishing Healthcare with Exquisite Solu?ons 28 20 24 Global Exploration Mirada C O V E R 36 Naviga?ng the Complex World of Medical Imaging Medical S T O R Y An Anecdote of Health, Demystifying Advancements Hope, and Healing! JANNIS FISCHER Understanding the DR. MAX AHNEN CEO and Co-founder Technology and Applica?ons COO and Co-founder POSITRIGO of Advanced Imaging POSITRIGO 32

  8. ISSUE 02 | MAY | 2023 THE Fujifilm Holdings Featuring Carestream Healthcare Encord holdings.fujifilm.com carestream.com encord.com Kenji Sukeno Company David Westgate Eric Landau Representa?ve Director & Chairman, President & CEO Co-founder and CEO Board Chairman Carestream Health Healthcare Brief Carestream Healthcare serves Encord offers a FujiFilm Holdings is comprised CI industrial markets globally comprehensive pla?orm to of more than 20 affiliate with non-destruc?ve tes?ng streamline data flows, companies spanning across a INSPIRING THE BUSINESS WORLD products, enabling customers create high quality training broad spectrum of industries CREDITS to capture high-quality images data through AI assisted including medical and life for applica?ons such as aircra? annota?on, and find & fix sciences, electronic, chemical, CREDITS inspec?on, assemblies, errors in your model to get graphic arts, informa?on cas?ngs and forensics. to produc?on AI faster. systems, mo?on picture, broadcast and photography. Chidiebere Moses O. Editor-in-Chief Prashik Bombarde Managing Editor Gilero Invicro LLC Medical Imaging Mirada Medical Featuring Execu?ve Editor Adiba Tarade gilero.com invicro.com Consultancy mirada-medical.com medicalimagingconsultancy.com Company Visualiser Jaine Woods Ted Mosler Roger Gunn Deepak Behera Jon DeVries CEO PhD, Chief Scien?fic Officer Managing Director CEO Art & Design Head Sonia Raizada Brief Gilero has become highly Invicro is an integral part Medical Imaging Mirada Medical's purpose Co-designer Bella Smith sought-a?er by industry of the REALM IDx, Inc. Consultancy approach is is to accelerate cancer Art & Design Assistant Paul White leaders and one of the group, which aims to strategy driven and care. They believe that by most trusted medical accelerate personalized customized to each need, making cancer care device design companies. medicine, discover novel understanding the universally available, free Business Development Manager Jane Adans From concept therapeu?c targets and constraints of ?me, of delays and equipped to development to contract develop innova?ve resources and logis?cs use the latest techniques Marke?ng Manager Lisa Jones manufacturing and design. therapeu?c technologies unique to each they can improve pa?ent Corporate Ofce Business Development Execu?ves Nancy B., Sarah M. for unmet medical needs. technology and company. outcomes and experience. Insights Success Media Tech LLC Michael D., Aaron S. Sales Execu?ves 555 Metro Place North, Suite 100, Dublin, OH 43017, United States Phone - (614)-859-2600 Siemens Healthcare Shimadzu Corpora?on Featuring Positrigo Technical Head Prachi Mokashi Email: info@thecioworld.com siemens-healthineers.com shimadzu.com positrigo.com David Walker For Subscription: www.thecioworld.com Assistant Technical Head Company Dr. Bernd Montag Jannis Fischer (CEO) & Yasunori Yamamoto Technical Consultants Lexi Morgan Follow us on CEO Dr. Max Ahnen (COO) President and CEO www.facebook.com/thecioworld Co-founders www.twitter.com/thecioworld Digital Marke?ng Manager Renuka Kulkarni Brief Positrigo vision is to make The analy?cal and Siemens Healthcare is at Jason Miller We are also available on Assistant Digital Marke?ng Manager func?onal imaging measuring instruments, the center of clinical Lilly Jacob SME-SMO Execu?ve accessible for people industrial machinery, and decision-making and worldwide and create a aircra? equipment that treatment pathways. RNI No.: MAHENG/2018/75953 las?ng social impact. Shimadzu Corpora?on Pa?ent-centered Research Analyst Sarah Miller Copyright © 2023 Insights Success Media and Technology provides are used in a innova?on has been and Pvt. Ltd., All rights reserved. The content and images used in wide range of industries. always will be at the core Nicole Smoot Circula?on Manager this magazine should not be reproduced or transmitted in of our company. any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from Insights Success. Reprint rights remain solely with Insights Success.

  9. ISSUE 02 | MAY | 2023 THE Fujifilm Holdings Featuring Carestream Healthcare Encord holdings.fujifilm.com carestream.com encord.com Kenji Sukeno Company David Westgate Eric Landau Representa?ve Director & Chairman, President & CEO Co-founder and CEO Board Chairman Carestream Health Healthcare Brief Carestream Healthcare serves Encord offers a FujiFilm Holdings is comprised CI industrial markets globally comprehensive pla?orm to of more than 20 affiliate with non-destruc?ve tes?ng streamline data flows, companies spanning across a INSPIRING THE BUSINESS WORLD products, enabling customers create high quality training broad spectrum of industries CREDITS to capture high-quality images data through AI assisted including medical and life for applica?ons such as aircra? annota?on, and find & fix sciences, electronic, chemical, inspec?on, assemblies, errors in your model to get graphic arts, informa?on cas?ngs and forensics. to produc?on AI faster. systems, mo?on picture, broadcast and photography. Chidiebere Moses O. Editor-in-Chief Prashik Bombarde Managing Editor Gilero Invicro LLC Medical Imaging Mirada Medical Featuring Execu?ve Editor Adiba Tarade gilero.com invicro.com Consultancy mirada-medical.com medicalimagingconsultancy.com Company Visualiser Jaine Woods Ted Mosler Roger Gunn Deepak Behera Jon DeVries CEO PhD, Chief Scien?fic Officer Managing Director CEO Art & Design Head Sonia Raizada Brief Gilero has become highly Invicro is an integral part Medical Imaging Mirada Medical's purpose Co-designer Bella Smith sought-a?er by industry of the REALM IDx, Inc. Consultancy approach is is to accelerate cancer Art & Design Assistant Paul White leaders and one of the group, which aims to strategy driven and care. They believe that by most trusted medical accelerate personalized customized to each need, making cancer care device design companies. medicine, discover novel understanding the universally available, free Business Development Manager Jane Adans From concept therapeu?c targets and constraints of ?me, of delays and equipped to development to contract develop innova?ve resources and logis?cs use the latest techniques Marke?ng Manager Lisa Jones manufacturing and design. therapeu?c technologies unique to each they can improve pa?ent Corporate Ofce Business Development Execu?ves Nancy B., Sarah M. for unmet medical needs. technology and company. outcomes and experience. Insights Success Media Tech LLC Michael D., Aaron S. Sales Execu?ves 555 Metro Place North, Suite 100, Dublin, OH 43017, United States Phone - (614)-859-2600 Siemens Healthcare Shimadzu Corpora?on Featuring Positrigo Technical Head Prachi Mokashi Email: info@thecioworld.com siemens-healthineers.com shimadzu.com positrigo.com David Walker For Subscription: www.thecioworld.com Assistant Technical Head Company Dr. Bernd Montag Jannis Fischer (CEO) & Yasunori Yamamoto Technical Consultants Lexi Morgan Follow us on CEO Dr. Max Ahnen (COO) President and CEO www.facebook.com/thecioworld Co-founders www.twitter.com/thecioworld Digital Marke?ng Manager Renuka Kulkarni Brief Positrigo vision is to make The analy?cal and Siemens Healthcare is at Jason Miller We are also available on Assistant Digital Marke?ng Manager func?onal imaging measuring instruments, the center of clinical Lilly Jacob SME-SMO Execu?ve accessible for people industrial machinery, and decision-making and worldwide and create a aircra? equipment that treatment pathways. RNI No.: MAHENG/2018/75953 las?ng social impact. Shimadzu Corpora?on Pa?ent-centered Research Analyst Sarah Miller Copyright © 2023 Insights Success Media and Technology provides are used in a innova?on has been and Pvt. Ltd., All rights reserved. The content and images used in wide range of industries. always will be at the core Nicole Smoot Circula?on Manager this magazine should not be reproduced or transmitted in of our company. any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from Insights Success. Reprint rights remain solely with Insights Success.

  10. The 10 Most Advanced Medical Imaging Solu?on Providers 2023 JANNIS FISCHER CEO and Co-founder POSITRIGO Enriching the Global Healthcare with Precise Imaging Solutions As a medical device manufacturer, we try to support them by offering a state-of-the-art imaging device at a fac?on of today´s cost. C O V E R S T O R Y

  11. The 10 Most Advanced Medical Imaging Solu?on Providers 2023 JANNIS FISCHER CEO and Co-founder POSITRIGO Enriching the Global Healthcare with Precise Imaging Solutions As a medical device manufacturer, we try to support them by offering a state-of-the-art imaging device at a fac?on of today´s cost. C O V E R S T O R Y

  12. hile examining any critical health condition, doctors identify and ascertain the reason for the W patient’s health situation by checking primary symptoms through the visible changes in skin, nails, hair, DR. MAX AHNEN and tongue to understand the eating and sleeping habits of COO and Co-founder the patient. POSITRIGO Moving further to pinpoint the exact illness, doctors insist to conduct pathological tests and several diagnostic procedures, including medical imaging techniques. In Positrigo imaging solu?ons recent healthcare advancements, medical imaging plays a have paved a new dimension significant role throughout the entire clinical process—from in the crucial diagnosis of diagnostics and treatment planning to—surgical procedures rapidly evolving diseases of and follow-up studies. Demen?a, Alzheimer’s disease, Modern advancements in medical science have brought Lewy Body Demen?a (LBD), forward specific and accurate imaging methods that give a Vascular Demen?a, and clear idea through images of the internal body organs of the Frontotemporal Demen?a, patients and provide accurate diagnostic results. respec?vely. Medical imaging gives an exact image of the affected organ or the body parts to be studied, enabling the doctors in having a clearer idea of the ailment and take decisions on the subsequent treatments. journey of making PET imaging more available and more affordable. Within this year the company will Providing innovative imaging solutions, Positrigo has be ready to help Dr. Buck and thousands of his peers emerged as a reliable MedTech organization that has made to do the imaging their patients in need for a proper value-added functional imaging accessible to people diagnosis. worldwide and has been creating a lasting social impact. Headquartered in Zurich, Switzerland, Positrigo is guided Guiding Leadership by its CEODr.Jannis Fischer and its COO Dr. Max Ahnen (both co-founders), in its journey of excellence. Jannis studied physics at FU and HU Berlin with exchanges to ETH Zurich, the University of California Los Angeles, Positrigo has been advancing the clinical routine by and CERN. During his PhD at ETH Zurich, he worked on facilitating broad research in diagnostics, treatment the development of SAFIR, a small animal PET system monitoring and the development of new therapies. With a with unprecedented temporal resolution. BPET (a SAFIR vision to make functional imaging accessible for people spin-off) started in 2017 with the grant of an ETH Pioneer worldwide and to create a lasting social impact. Positrigo Fellowship to Max and Jannis. Since then, other awards makes functional imaging scalable – “imaging everyone!” have followed, e. g. VentureKick and Forbes Europe 30 under 30. Visionary Inspirations The saga of this phenomenal organization began when In 2017, Prof. em. Dr. Alfred Buck – the former head of the Jannis Fischer and Max Ahnen were PhD students in NeuroPET program at University Hospital Zurich - came to particle physics and the above idea was conceived. With Positrigo with a vision to develop a dedicated brain their background in detector design and construction as well Positron Emission Tomography (PET) system. One field of as software development, they managed to build a fully use is Alzheimer’s disease, whose hallmarks can be seen in functional prototype within two years. It was used to scan PET. As more than 100 drugs are on the horizon – 2 of them JANNIS FISCHER ten patients in a pilot clinical trial. This system was the already FDA-cleared – as an urgent matter. Based on its basis for the company Positrigo, which has since built a CEO and Co-founder know-how from particle physics on how to design and build team of engineers working on making it a medical device. complex detector systems, the Positrigo team went onto the POSITRIGO

  13. hile examining any critical health condition, doctors identify and ascertain the reason for the W patient’s health situation by checking primary symptoms through the visible changes in skin, nails, hair, DR. MAX AHNEN and tongue to understand the eating and sleeping habits of COO and Co-founder the patient. POSITRIGO Moving further to pinpoint the exact illness, doctors insist to conduct pathological tests and several diagnostic procedures, including medical imaging techniques. In Positrigo imaging solu?ons recent healthcare advancements, medical imaging plays a have paved a new dimension significant role throughout the entire clinical process—from in the crucial diagnosis of diagnostics and treatment planning to—surgical procedures rapidly evolving diseases of and follow-up studies. Demen?a, Alzheimer’s disease, Modern advancements in medical science have brought Lewy Body Demen?a (LBD), forward specific and accurate imaging methods that give a Vascular Demen?a, and clear idea through images of the internal body organs of the Frontotemporal Demen?a, patients and provide accurate diagnostic results. respec?vely. Medical imaging gives an exact image of the affected organ or the body parts to be studied, enabling the doctors in having a clearer idea of the ailment and take decisions on the subsequent treatments. journey of making PET imaging more available and more affordable. Within this year the company will Providing innovative imaging solutions, Positrigo has be ready to help Dr. Buck and thousands of his peers emerged as a reliable MedTech organization that has made to do the imaging their patients in need for a proper value-added functional imaging accessible to people diagnosis. worldwide and has been creating a lasting social impact. Headquartered in Zurich, Switzerland, Positrigo is guided Guiding Leadership by its CEODr.Jannis Fischer and its COO Dr. Max Ahnen (both co-founders), in its journey of excellence. Jannis studied physics at FU and HU Berlin with exchanges to ETH Zurich, the University of California Los Angeles, Positrigo has been advancing the clinical routine by and CERN. During his PhD at ETH Zurich, he worked on facilitating broad research in diagnostics, treatment the development of SAFIR, a small animal PET system monitoring and the development of new therapies. With a with unprecedented temporal resolution. BPET (a SAFIR vision to make functional imaging accessible for people spin-off) started in 2017 with the grant of an ETH Pioneer worldwide and to create a lasting social impact. Positrigo Fellowship to Max and Jannis. Since then, other awards makes functional imaging scalable – “imaging everyone!” have followed, e. g. VentureKick and Forbes Europe 30 under 30. Visionary Inspirations The saga of this phenomenal organization began when In 2017, Prof. em. Dr. Alfred Buck – the former head of the Jannis Fischer and Max Ahnen were PhD students in NeuroPET program at University Hospital Zurich - came to particle physics and the above idea was conceived. With Positrigo with a vision to develop a dedicated brain their background in detector design and construction as well Positron Emission Tomography (PET) system. One field of as software development, they managed to build a fully use is Alzheimer’s disease, whose hallmarks can be seen in functional prototype within two years. It was used to scan PET. As more than 100 drugs are on the horizon – 2 of them JANNIS FISCHER ten patients in a pilot clinical trial. This system was the already FDA-cleared – as an urgent matter. Based on its basis for the company Positrigo, which has since built a CEO and Co-founder know-how from particle physics on how to design and build team of engineers working on making it a medical device. complex detector systems, the Positrigo team went onto the POSITRIGO

  14. Positrigo’s vision is to ‘imaging everyone,’ which means that it wants to broaden the availability of func?onal imaging and to allow a wide range of pa?ents with brain-related disorders the access to precision imaging.

  15. Positrigo’s vision is to ‘imaging everyone,’ which means that it wants to broaden the availability of func?onal imaging and to allow a wide range of pa?ents with brain-related disorders the access to precision imaging.

  16. By the end of 2023, the management expects to have Alzheimer’s disease has been a serious concern that affects regulatory approval in Europe to start marketing the around 40 million individuals worldwide, causing a device. tremendous medical and socio-economic burden. Specialized dementia diagnosis is critical to be able to offer individualized therapy and to monitor treatment progress. Driving Fundamentals This is precisely why Positrigo has developed a solution which assists in making specialized Alzheimer’s disease Positrigo’s vision is to “imaging everyone,” which diagnostic more broadly available. means that it wants to broaden the availability of functional imaging and to allow a wide range of LBD or the Lewy body dementia (LBD), is a disease patients with brain-related disorders the access to associated with abnormal deposits of a protein called alpha- precision imaging. The company is built around the synuclein in the brain. These deposits, called Lewy bodies, following core values: affect chemicals in the brain whose changes, in turn, can lead to problems with thinking, movement, behavior, and 1. Customer Focus - We put customers first mood. The Positrigo imaging solutions help the doctors in 2. Quality - We demand excellence tracing alpha-synuclein and help to identify the possibilities 3. Collaboration - We work well together of LBD. 4. Passion and Commitment - We care Vascular dementia is basically referring to describing Key Differentiators problems with reasoning, planning, judgment, memory, and other thought processes caused by brain damage from The product offering of Positrigo is unique as impaired blood flow to the brain. Factors that increase the NeuroLF, is one of the smallest dedicated brain PET risk of heart disease and stroke — including diabetes, high systems coming to market in 2023. Beside the ultra- blood pressure, high cholesterol and smoking — also raise compact design, the device offers high patient comfort the vascular dementia risk. Controlling these factors may and satisfaction, it comes with an attractive price-value help lower the chances of developing vascular dementia. proposition and is intuitive and easy to use. Positrigo imaging helps in detecting after such and elements that can identify the possibilities of severe diseases, thereby NeuroLF offers a variety of USPs, namely… offering the doctors with the right direction in diagnosis and offering the proper consultation to the patients with Ÿ Limited space requirements convincing evidence, making them aware of the gravity of Ÿ Intuitive and easy to use the situation and encourage their cooperation in the Ÿ High patient comfort and satisfaction treatments. Ÿ Compelling price-value proposition NeuroLF is an efficient and reliable imaging system that Positrigo’s imaging solutions have paved a new dimension can help in diagnosing Frontotemporal Dementia. in the crucial diagnosis of rapidly evolving diseases of Frontotemporal dementia (FTD), a common cause of Dementia, including Alzheimer’s disease, Lewy Body dementia, is a group of disorders that occur when nerve Positrigo has been Dementia (LBD), Vascular Dementia, and Frontotemporal cells in the frontal and temporal lobes of the brain are lost. Dementia, respectively. advancing the clinical This causes the lobes to shrink. These shrinkages are rou?ne by facilita?ng neurodegeneration, which is visible through the NeuroLF Abnormal brain changes cause the disorders grouped under broad research in imaging of neurodegeneration tracers. the general term “dementia”. These changes trigger a decline in thinking skills, also known as cognitive abilities, diagnos?cs, treatment In Neuro Oncology, over the past decades, brain PET with severe enough to impair daily life and independent monitoring and the numerous radiolabelled molecules has been evaluated to function. When there is no test to determine if some patient development of new overcome limitations of conventional MRI in the Neuro- has dementia, the physicians diagnose types of dementia Oncology assessment. The task force of the Response based on a careful medical history, a physical examination, therapies Assessment in Neuro-Oncology (RANO) working group laboratory tests and functional imaging. Among the various emphasized that for gliomas, the additional clinical value of tests, Positron Emission Tomography (PET) is known as the radiolabelled amino acids compared with standard MRI is gold standard in functional imaging for dementia diagnosis. outstanding and justifies the widespread clinical use.

  17. By the end of 2023, the management expects to have Alzheimer’s disease has been a serious concern that affects regulatory approval in Europe to start marketing the around 40 million individuals worldwide, causing a device. tremendous medical and socio-economic burden. Specialized dementia diagnosis is critical to be able to offer individualized therapy and to monitor treatment progress. Driving Fundamentals This is precisely why Positrigo has developed a solution which assists in making specialized Alzheimer’s disease Positrigo’s vision is to “imaging everyone,” which diagnostic more broadly available. means that it wants to broaden the availability of functional imaging and to allow a wide range of LBD or the Lewy body dementia (LBD), is a disease patients with brain-related disorders the access to associated with abnormal deposits of a protein called alpha- precision imaging. The company is built around the synuclein in the brain. These deposits, called Lewy bodies, following core values: affect chemicals in the brain whose changes, in turn, can lead to problems with thinking, movement, behavior, and 1. Customer Focus - We put customers first mood. The Positrigo imaging solutions help the doctors in 2. Quality - We demand excellence tracing alpha-synuclein and help to identify the possibilities 3. Collaboration - We work well together of LBD. 4. Passion and Commitment - We care Vascular dementia is basically referring to describing Key Differentiators problems with reasoning, planning, judgment, memory, and other thought processes caused by brain damage from The product offering of Positrigo is unique as impaired blood flow to the brain. Factors that increase the NeuroLF, is one of the smallest dedicated brain PET risk of heart disease and stroke — including diabetes, high systems coming to market in 2023. Beside the ultra- blood pressure, high cholesterol and smoking — also raise compact design, the device offers high patient comfort the vascular dementia risk. Controlling these factors may and satisfaction, it comes with an attractive price-value help lower the chances of developing vascular dementia. proposition and is intuitive and easy to use. Positrigo imaging helps in detecting after such and elements that can identify the possibilities of severe diseases, thereby NeuroLF offers a variety of USPs, namely… offering the doctors with the right direction in diagnosis and offering the proper consultation to the patients with Ÿ Limited space requirements convincing evidence, making them aware of the gravity of Ÿ Intuitive and easy to use the situation and encourage their cooperation in the Ÿ High patient comfort and satisfaction treatments. Ÿ Compelling price-value proposition NeuroLF is an efficient and reliable imaging system that Positrigo’s imaging solutions have paved a new dimension can help in diagnosing Frontotemporal Dementia. in the crucial diagnosis of rapidly evolving diseases of Frontotemporal dementia (FTD), a common cause of Dementia, including Alzheimer’s disease, Lewy Body dementia, is a group of disorders that occur when nerve Positrigo has been Dementia (LBD), Vascular Dementia, and Frontotemporal cells in the frontal and temporal lobes of the brain are lost. Dementia, respectively. advancing the clinical This causes the lobes to shrink. These shrinkages are rou?ne by facilita?ng neurodegeneration, which is visible through the NeuroLF Abnormal brain changes cause the disorders grouped under broad research in imaging of neurodegeneration tracers. the general term “dementia”. These changes trigger a decline in thinking skills, also known as cognitive abilities, diagnos?cs, treatment In Neuro Oncology, over the past decades, brain PET with severe enough to impair daily life and independent monitoring and the numerous radiolabelled molecules has been evaluated to function. When there is no test to determine if some patient development of new overcome limitations of conventional MRI in the Neuro- has dementia, the physicians diagnose types of dementia Oncology assessment. The task force of the Response based on a careful medical history, a physical examination, therapies Assessment in Neuro-Oncology (RANO) working group laboratory tests and functional imaging. Among the various emphasized that for gliomas, the additional clinical value of tests, Positron Emission Tomography (PET) is known as the radiolabelled amino acids compared with standard MRI is gold standard in functional imaging for dementia diagnosis. outstanding and justifies the widespread clinical use.

  18. previously trained clinicians. Positrigo provides the latest It is known that amino acid PET can help to define updates on its developments through its clinical newsletters metabolic hotspots for specific tumour tissue sampling, a on the following topics of technique that can be particularly useful if biopsy rather than open resection is considered. Ÿ Clinical Training on Demand Ÿ Educational Webinars For neuro-oncologists and medical professionals involved Ÿ Whitepapers and Case Stories in the diagnosis and care of patients with brain tumors, the Ÿ Continuing Education Opportunities following three indications for PET imaging are of particular clinical interest: Expert Opinion Ÿ The identification of neoplastic tissue, including the Speaking from the industry perspective, Jannis says, “The delineation of tumor extent for the further diagnostic I am happy and proud healthcare sector is a very challenging sector where the and therapeutic management delivery of high-quality patient care contrasts with Ÿ The differentiation of treatment related changes from to say that we have permanent cost pressure. Therefore, it is – in my view - tumor progression at follow-up been very fortunate at critical for healthcare providers to constantly look for Ÿ The assessment of response to a certain anticancer Positrigo to a?ract the improvements, process optimizations and to remain therapy, including its (predictive) effect on the patients’ innovative. As a medical device manufacturer, we try to outcome right talent to develop support them by offering a state-of-the-art imaging device cu?ng-edge imaging at a faction of today’s cost.” Epilepsy is one condition that might occur because of a technologies. genetic disorder or an acquired brain injury, such as a Reflecting Experience trauma or stroke. During a seizure, a person experiences abnormal behaviour, symptoms, and sensations, sometimes Replying as an advice to the young medical professionals, including loss of consciousness. Jannis said, “My advice to entrepreneurs and enthusiasts aspiring to venture into the medical imaging niche is to stay For patients with epilepsy a PET scan is used to localize the very close to clinicians who are using the imaging part of the brain that is causing the seizure activity. There technology on a daily basis. This will allow you to design a are various PET tracers to measure glucose, serotonin and solution-centred device and a technology that the end users oxygen metabolism, cerebral blood flow and receptor will accept. binding in epilepsy. Imaging brain glucose metabolism with 18Fluoro-2-deoxyglucose (FDG) PET is the most utilized In addition, it is prudent to bring a team of subject matter technique in routine clinical practice. experts together as the development of imaging technology is highly complex and requires unique expertise and skill Making an Impact sets. I am happy and proud to say that we have been very fortunate at Positrigo to attract the right talent to develop The vision and goals are designed to make functional cutting-edge imaging technologies.” imaging accessible to everyone. Positrigo has planned to accomplish this by developing a dedicated brain PET Expanding in Newer Geographies system that is capable to offer functional imaging with the same quality and performance standards as the much larger Positrigo’s plan to scale newer horizons is by bringing its whole-body devices but at a fraction of today’s cost. This first product to market in Europe in 2023. Together with its would allow even smaller neurologist offices to offer brain dedicated sales partners, it plans to deliver the first devices PET imaging thus enabling much more patients to benefit and to recognize revenue by the end of this year. In 2024 from this highly precise diagnostic modality. the company expects to obtain FDA clearance for its technology which will allow it to penetrate the US From the Beginning to the End geographies. For this reason, Positrigo aims to grow its sales team in the US, focusing on becoming the market Besides the initial product training Positrigo team is always leader for dedicated brain PET systems with the vision to ready to help and be of support along the way. It offers “imaging everyone”. trainings on demand for the new employees and / or prepares continuing education opportunities for the

  19. previously trained clinicians. Positrigo provides the latest It is known that amino acid PET can help to define updates on its developments through its clinical newsletters metabolic hotspots for specific tumour tissue sampling, a on the following topics of technique that can be particularly useful if biopsy rather than open resection is considered. Ÿ Clinical Training on Demand Ÿ Educational Webinars For neuro-oncologists and medical professionals involved Ÿ Whitepapers and Case Stories in the diagnosis and care of patients with brain tumors, the Ÿ Continuing Education Opportunities following three indications for PET imaging are of particular clinical interest: Expert Opinion Ÿ The identification of neoplastic tissue, including the Speaking from the industry perspective, Jannis says, “The delineation of tumor extent for the further diagnostic I am happy and proud healthcare sector is a very challenging sector where the and therapeutic management delivery of high-quality patient care contrasts with Ÿ The differentiation of treatment related changes from to say that we have permanent cost pressure. Therefore, it is – in my view - tumor progression at follow-up been very fortunate at critical for healthcare providers to constantly look for Ÿ The assessment of response to a certain anticancer Positrigo to a?ract the improvements, process optimizations and to remain therapy, including its (predictive) effect on the patients’ innovative. As a medical device manufacturer, we try to outcome right talent to develop support them by offering a state-of-the-art imaging device cu?ng-edge imaging at a faction of today’s cost.” Epilepsy is one condition that might occur because of a technologies. genetic disorder or an acquired brain injury, such as a Reflecting Experience trauma or stroke. During a seizure, a person experiences abnormal behaviour, symptoms, and sensations, sometimes Replying as an advice to the young medical professionals, including loss of consciousness. Jannis said, “My advice to entrepreneurs and enthusiasts aspiring to venture into the medical imaging niche is to stay For patients with epilepsy a PET scan is used to localize the very close to clinicians who are using the imaging part of the brain that is causing the seizure activity. There technology on a daily basis. This will allow you to design a are various PET tracers to measure glucose, serotonin and solution-centred device and a technology that the end users oxygen metabolism, cerebral blood flow and receptor will accept. binding in epilepsy. Imaging brain glucose metabolism with 18Fluoro-2-deoxyglucose (FDG) PET is the most utilized In addition, it is prudent to bring a team of subject matter technique in routine clinical practice. experts together as the development of imaging technology is highly complex and requires unique expertise and skill Making an Impact sets. I am happy and proud to say that we have been very fortunate at Positrigo to attract the right talent to develop The vision and goals are designed to make functional cutting-edge imaging technologies.” imaging accessible to everyone. Positrigo has planned to accomplish this by developing a dedicated brain PET Expanding in Newer Geographies system that is capable to offer functional imaging with the same quality and performance standards as the much larger Positrigo’s plan to scale newer horizons is by bringing its whole-body devices but at a fraction of today’s cost. This first product to market in Europe in 2023. Together with its would allow even smaller neurologist offices to offer brain dedicated sales partners, it plans to deliver the first devices PET imaging thus enabling much more patients to benefit and to recognize revenue by the end of this year. In 2024 from this highly precise diagnostic modality. the company expects to obtain FDA clearance for its technology which will allow it to penetrate the US From the Beginning to the End geographies. For this reason, Positrigo aims to grow its sales team in the US, focusing on becoming the market Besides the initial product training Positrigo team is always leader for dedicated brain PET systems with the vision to ready to help and be of support along the way. It offers “imaging everyone”. trainings on demand for the new employees and / or prepares continuing education opportunities for the

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  22. 10 Most Advanced Medical Imaging Solu?on Providers 2023 Eric Landau Co-founder and CEO Encord Stringing a Powerful Cord of Futuris?c Data-Centric Computer Vision nnovations do not have to be always solving huge labels. Again the result was outstanding with the highest problems. Rather powerful innovations are those expense clinician seeing 16X labelling efficiency I which solve everyday issues for those who are the improvement, cutting down the model development time most important social contributors like healthcare givers. from one year to two months and a 6.4X average increase in This is the story of such an innovative company which is labelling efficiency for GI videos. stringing a powerful cord between technology and healthcare professionals by using futuristic data-centric Furthermore, MSK adopted Encord to build custom label computer vision. structures for pulmonary thrombosis projects, thus making them entirely feasible for the company. Today, Machine Doctors in the Division of Nephrology, at Stanford learning and data operations teams of all sizes use Medicine, were facing a complex problem. They had to use Encord's collaborative applications, automation features, three different kinds of software to identify, annotate, and and APIs to build models and annotate, manage, and count podocytes and glomeruli in microscopy images. evaluate their datasets. Similarly, King's College London had been using clinicians to annotate pre-cancerous polyp videos had prohibitively In Eric's words, "We work with some of the world's leading high costs to produce large datasets. Likewise, Memorial AI companies, enterprises, hospitals, and research Sloan Kettering Cancer Center staff were finding detecting institutions." and classifying vena cava filters in complex label structures (ontologies) rendered existing and open-source tools Elaborating on his own journey Erics shares that during his unusable. undergrad, he studied physics. He began a PhD but left to take a job in finance. After almost a decade of working in Simply, in the words of King's College's Director for finance, Eric was ready for a new challenge. He joined an Gastroenterology and Endoscopy, this has been like mental entrepreneur network here in London, which is where he torture to them. As the director and many more heads of met Ulrik. Ulrik told Eric about his seed idea for Encord, Encord was named by CB Insights as one of the 100 most promising private AI such institutions were living in the agony thinking they had stressing the need to solve the data bottleneck by companies of 2022. In this interview, King’s College Hospital’s Director for to endure it lifelong, came along Encord and using the automating data annotation in medical AI and beyond. Gastroenterology and Endoscopy Dr Bu Hayee discusses how Encord’s tool power of advanced technologies like AI and ML, first its Encord's eliminated the “mental torture” of manual data labelling. Co-founder and CEO, Eric Landau convinced Stanford to Erics reveals, "I thought it was the best startup idea I had use Encord's annotation tools and SDK to automate heard, and it was a lot better than the ones I had had, so we Hall of In this NVIDIA post, Fareedc Iqbal, the CEO of SurgEase, a company that offers segmentations, count, and calculate sizes of segments. The founded the company and began solving the problems telepresence technology for gastroenterology, said, “Encord’s so?ware has been result was astonishing, as with Encord, Stanford researchers associated with putting together and managing high-quality Fame instrumental in aiding us in solving some of the hardest problems in endoscopic reduced experiment duration from an average of 21 to 4 training data for machine learning models." days (80%) while processing 3X the number of images. disease assessment.” In an interview with The CIO World, Eric spoke at length Eric also convinced Dr Bu Hayee, the Director from King's about the inception, the journey and their future plans for Encord’s technology has been used by Stanford University, King’s College London, College to deploy Encord's micro-model module to increase Encord. and Memorial Sloan Ke?ering. Case studies with links to academic papers are clinician labelling efficiency and automate 97% of produced available on Encord’s website h?ps://encord.com/ MAY, 2023 MAY, 2023 www.thecioworld.com www.thecioworld.com 20 21

  23. 10 Most Advanced Medical Imaging Solu?on Providers 2023 Eric Landau Co-founder and CEO Encord Stringing a Powerful Cord of Futuris?c Data-Centric Computer Vision nnovations do not have to be always solving huge labels. Again the result was outstanding with the highest problems. Rather powerful innovations are those expense clinician seeing 16X labelling efficiency I which solve everyday issues for those who are the improvement, cutting down the model development time most important social contributors like healthcare givers. from one year to two months and a 6.4X average increase in This is the story of such an innovative company which is labelling efficiency for GI videos. stringing a powerful cord between technology and healthcare professionals by using futuristic data-centric Furthermore, MSK adopted Encord to build custom label computer vision. structures for pulmonary thrombosis projects, thus making them entirely feasible for the company. Today, Machine Doctors in the Division of Nephrology, at Stanford learning and data operations teams of all sizes use Medicine, were facing a complex problem. They had to use Encord's collaborative applications, automation features, three different kinds of software to identify, annotate, and and APIs to build models and annotate, manage, and count podocytes and glomeruli in microscopy images. evaluate their datasets. Similarly, King's College London had been using clinicians to annotate pre-cancerous polyp videos had prohibitively In Eric's words, "We work with some of the world's leading high costs to produce large datasets. Likewise, Memorial AI companies, enterprises, hospitals, and research Sloan Kettering Cancer Center staff were finding detecting institutions." and classifying vena cava filters in complex label structures (ontologies) rendered existing and open-source tools Elaborating on his own journey Erics shares that during his unusable. undergrad, he studied physics. He began a PhD but left to take a job in finance. After almost a decade of working in Simply, in the words of King's College's Director for finance, Eric was ready for a new challenge. He joined an Gastroenterology and Endoscopy, this has been like mental entrepreneur network here in London, which is where he torture to them. As the director and many more heads of met Ulrik. Ulrik told Eric about his seed idea for Encord, Encord was named by CB Insights as one of the 100 most promising private AI such institutions were living in the agony thinking they had stressing the need to solve the data bottleneck by companies of 2022. In this interview, King’s College Hospital’s Director for to endure it lifelong, came along Encord and using the automating data annotation in medical AI and beyond. Gastroenterology and Endoscopy Dr Bu Hayee discusses how Encord’s tool power of advanced technologies like AI and ML, first its Encord's eliminated the “mental torture” of manual data labelling. Co-founder and CEO, Eric Landau convinced Stanford to Erics reveals, "I thought it was the best startup idea I had use Encord's annotation tools and SDK to automate heard, and it was a lot better than the ones I had had, so we Hall of In this NVIDIA post, Fareedc Iqbal, the CEO of SurgEase, a company that offers segmentations, count, and calculate sizes of segments. The founded the company and began solving the problems telepresence technology for gastroenterology, said, “Encord’s so?ware has been result was astonishing, as with Encord, Stanford researchers associated with putting together and managing high-quality Fame instrumental in aiding us in solving some of the hardest problems in endoscopic reduced experiment duration from an average of 21 to 4 training data for machine learning models." days (80%) while processing 3X the number of images. disease assessment.” In an interview with The CIO World, Eric spoke at length Eric also convinced Dr Bu Hayee, the Director from King's about the inception, the journey and their future plans for Encord’s technology has been used by Stanford University, King’s College London, College to deploy Encord's micro-model module to increase Encord. and Memorial Sloan Ke?ering. Case studies with links to academic papers are clinician labelling efficiency and automate 97% of produced available on Encord’s website h?ps://encord.com/ MAY, 2023 MAY, 2023 www.thecioworld.com www.thecioworld.com 20 21

  24. Herein are the highlights of that exclusive interview! However, until recently, the AI world has been very model- centric, so healthcare professionals haven't been able to use Eric, please brief our audience about Encord and kindly AI to its full potential. By taking a data-centric approach to tell us the source of inspiration for venturing into the AI and focusing on improving the quality and quantity of medical imaging niche. the training data used to train medical AI models, we can eliminate potential demographic biases and make model We are an early-stage startup that provides a computer- predictions as realistic as possible to what happens in a vision-first platform for annotating and managing training clinical setting. Because we want medical professionals to data. When my co-founder Ulrik was studying at Imperial be able to use AI in practice in a way that's consistent with College London, he worked on a project where he was the values of the medical profession, Encord has focused on visualizing scale image datasets for medical AI. Through delivering an efficient, user-friendly platform that allows this work, he realized the difficulties that doctors face when for all the security, privacy, and integrity expected when labelling these images. Hand labelling medical images take handling patient data. an enormous amount of time, so Encord started off working in the medical imaging field because he understood how Kindly elaborate upon the services that make Encord suboptimal the data annotation process was, and how it stand out as one of themost advanced medical imaging could be done a lot more efficiently if doctors had a solution providers in the modern healthcare industry. technological solution for it. We are technologically focused. We knew this problem Can you elaborate upon the core values on which needed a more sustainable, long-term solution than the Encord is built, what is its vision and mission? current solutions which were built upon improving manual labelling processes or increasing the amount of manual At Encord, we value curiosity and a growth mentality. Our labellers. Rather than continue to throw a lot of doctors at team prioritizes humility– being willing to learn from the problem, we wanted to create a technological solution mistakes– and resourcefulness–being scrappy and creative that used doctors' time as efficiently as possible. The micro- when solving new problems– which enables them to model technology we developed enables doctors to develop great products and deliver high-quality customer automate data labelling with just a handful of manually support. labelled images. We are the only company that provides an automated solution to the problem of annotating training Encord's mission is to accelerate the pace of data-centric data. AI in medicine so that healthcare institutions and medical A healthcare provider could use a very sophisticated model, Talk to doctors, nurses, AI professionals, and as many other professionals can reap the benefits of this technology. AI We are also very hands-on from a company-to-consumer but if the model hasn't been trained on a vast amount of data stakeholders as you can. Really listen to them to understand has the potential to make healthcare and medical treatments perspective. We don't throw one-size-fits-all solutions at a that is reflective of the patient population, then the their experience and the challenges they're encountering. A lot increasingly proactive rather than reactive. problem; instead, we really try to understand each technology and its outputs will be fundamentally flawed. of entrepreneurs will speak first and say, "This is what I think individual customer's needs to make sure they get the the problem is," but that's not the right approach. solution most likely to work for their existing issues. Healthcare providers need to put processes in place that Encord's mission is to validate the technology and make sure it delivers valuable, First, you listen, then you synthesize the information you've What is your opinion on healthcare providers' aligning real-world patient care. Conditional upon that, they learned in all of these conversations to understand the accelerate the pace of their offerings with newer technological developments, shouldn't be shy about or afraid of using technology problem, and finally, you begin to formulate a solution from especially when it comes to catering to the dynamic data-centric AI in because it can be immensely useful in delivering patient that starting point. needs of the healthcare space? care. medicine so that How do you envision scaling Encord's services and We are technologically forward-thinking, so we encourage What advice would you like to give to the budding operations in 2023 and beyond? healthcare institutions healthcare providers to align their offerings with newer entrepreneurs and enthusiasts aspiring to venture into technological developments. That said, those technological and medical the medical imaging niche that you are catering to? We're going to continue the growth of the team and expand solutions also have to work and deliver real-world value, so geographically, with a particular focus on the U.S. market professionals can reap the technology shouldn't just be used because of the hype Don't assume you know the answer to the problem or even where we are working to establish a stronger presence. We surrounding it. When it comes to machine learning, this is the problem itself. You need to talk to a lot of people to also have exciting new healthcare-focused partnerships in the the benefits of this where the power of data-centric AI really comes into play. understand the problem and its solution. Don't be shy about works, with some of the world's best academic institutions and talking to people. industrial AI partners. technology. MAY, 2023 MAY, 2023 www.thecioworld.com www.thecioworld.com 22 23

  25. Herein are the highlights of that exclusive interview! However, until recently, the AI world has been very model- centric, so healthcare professionals haven't been able to use Eric, please brief our audience about Encord and kindly AI to its full potential. By taking a data-centric approach to tell us the source of inspiration for venturing into the AI and focusing on improving the quality and quantity of medical imaging niche. the training data used to train medical AI models, we can eliminate potential demographic biases and make model We are an early-stage startup that provides a computer- predictions as realistic as possible to what happens in a vision-first platform for annotating and managing training clinical setting. Because we want medical professionals to data. When my co-founder Ulrik was studying at Imperial be able to use AI in practice in a way that's consistent with College London, he worked on a project where he was the values of the medical profession, Encord has focused on visualizing scale image datasets for medical AI. Through delivering an efficient, user-friendly platform that allows this work, he realized the difficulties that doctors face when for all the security, privacy, and integrity expected when labelling these images. Hand labelling medical images take handling patient data. an enormous amount of time, so Encord started off working in the medical imaging field because he understood how Kindly elaborate upon the services that make Encord suboptimal the data annotation process was, and how it stand out as one of themost advanced medical imaging could be done a lot more efficiently if doctors had a solution providers in the modern healthcare industry. technological solution for it. We are technologically focused. We knew this problem Can you elaborate upon the core values on which needed a more sustainable, long-term solution than the Encord is built, what is its vision and mission? current solutions which were built upon improving manual labelling processes or increasing the amount of manual At Encord, we value curiosity and a growth mentality. Our labellers. Rather than continue to throw a lot of doctors at team prioritizes humility– being willing to learn from the problem, we wanted to create a technological solution mistakes– and resourcefulness–being scrappy and creative that used doctors' time as efficiently as possible. The micro- when solving new problems– which enables them to model technology we developed enables doctors to develop great products and deliver high-quality customer automate data labelling with just a handful of manually support. labelled images. We are the only company that provides an automated solution to the problem of annotating training Encord's mission is to accelerate the pace of data-centric data. AI in medicine so that healthcare institutions and medical A healthcare provider could use a very sophisticated model, Talk to doctors, nurses, AI professionals, and as many other professionals can reap the benefits of this technology. AI We are also very hands-on from a company-to-consumer but if the model hasn't been trained on a vast amount of data stakeholders as you can. Really listen to them to understand has the potential to make healthcare and medical treatments perspective. We don't throw one-size-fits-all solutions at a that is reflective of the patient population, then the their experience and the challenges they're encountering. A lot increasingly proactive rather than reactive. problem; instead, we really try to understand each technology and its outputs will be fundamentally flawed. of entrepreneurs will speak first and say, "This is what I think individual customer's needs to make sure they get the the problem is," but that's not the right approach. solution most likely to work for their existing issues. Healthcare providers need to put processes in place that Encord's mission is to validate the technology and make sure it delivers valuable, First, you listen, then you synthesize the information you've What is your opinion on healthcare providers' aligning real-world patient care. Conditional upon that, they learned in all of these conversations to understand the accelerate the pace of their offerings with newer technological developments, shouldn't be shy about or afraid of using technology problem, and finally, you begin to formulate a solution from especially when it comes to catering to the dynamic data-centric AI in because it can be immensely useful in delivering patient that starting point. needs of the healthcare space? care. medicine so that How do you envision scaling Encord's services and We are technologically forward-thinking, so we encourage What advice would you like to give to the budding operations in 2023 and beyond? healthcare institutions healthcare providers to align their offerings with newer entrepreneurs and enthusiasts aspiring to venture into technological developments. That said, those technological and medical the medical imaging niche that you are catering to? We're going to continue the growth of the team and expand solutions also have to work and deliver real-world value, so geographically, with a particular focus on the U.S. market professionals can reap the technology shouldn't just be used because of the hype Don't assume you know the answer to the problem or even where we are working to establish a stronger presence. We surrounding it. When it comes to machine learning, this is the problem itself. You need to talk to a lot of people to also have exciting new healthcare-focused partnerships in the the benefits of this where the power of data-centric AI really comes into play. understand the problem and its solution. Don't be shy about works, with some of the world's best academic institutions and talking to people. industrial AI partners. technology. MAY, 2023 MAY, 2023 www.thecioworld.com www.thecioworld.com 22 23

  26. Global Exploration Navigating Complex WORLD the of MEDICAL IMAGING Furthermore, the integration of artificial intelligence (AI) edical imaging is a rapidly evolving field that algorithms has revolutionized medical imaging by plays a vital role in modern healthcare. It automating processes, assisting in image interpretation, and M encompasses various imaging modalities and aiding in the detection of abnormalities. technologies that enable healthcare professionals to visualize and diagnose a wide range of medical conditions. Applications in Diagnostic Medicine Further, we embark on a global exploration of the complex Medical imaging plays a critical role in the diagnosis and world of medical imaging, delving into its advancements, management of various medical conditions. X-rays are challenges, and impact on patient care! commonly used to evaluate fractures, detect lung diseases, and assess dental health. Ultrasound is invaluable in The Evolution of Medical Imaging prenatal care, assessing cardiac function, and detecting abnormalities in organs such as the liver, kidneys, and The journey of medical imaging began with the discovery reproductive system. CT scans provide detailed cross- of X-rays by Wilhelm Conrad Roentgen in 1895. Since sectional images, aiding in the diagnosis of cancer, then, the field has experienced remarkable advancements, cardiovascular diseases, and neurological conditions. MRI with the development of technologies such as ultrasound, offers exceptional soft tissue contrast, making it particularly computed tomography (CT), magnetic resonance imaging valuable in diagnosing brain, spinal, and musculoskeletal (MRI), and nuclear medicine. Each imaging modality offers disorders. Nuclear medicine techniques, including positron unique capabilities and is used for specific diagnostic emission tomography (PET), enable the visualization of purposes, contributing to the comprehensive toolkit metabolic activity, aiding in the detection and staging of available to healthcare professionals. cancer, cardiac diseases, and neurological conditions. Advancements in Imaging Technology Challenges and Limitations In recent years, medical imaging technology has undergone While medical imaging has transformed healthcare, it is not significant advancements, revolutionizing the field. Digital without challenges and limitations. One significant concern imaging has replaced traditional film-based techniques, is the increasing demand for imaging services, leading to providing enhanced image quality, faster image acquisition, longer wait times and potential delays in diagnosis. and improved storage and accessibility of patient data. MAY, 2023 MAY, 2023 www.thecioworld.com www.thecioworld.com 24 25

  27. Global Exploration Navigating Complex WORLD the of MEDICAL IMAGING Furthermore, the integration of artificial intelligence (AI) edical imaging is a rapidly evolving field that algorithms has revolutionized medical imaging by plays a vital role in modern healthcare. It automating processes, assisting in image interpretation, and M encompasses various imaging modalities and aiding in the detection of abnormalities. technologies that enable healthcare professionals to visualize and diagnose a wide range of medical conditions. Applications in Diagnostic Medicine Further, we embark on a global exploration of the complex Medical imaging plays a critical role in the diagnosis and world of medical imaging, delving into its advancements, management of various medical conditions. X-rays are challenges, and impact on patient care! commonly used to evaluate fractures, detect lung diseases, and assess dental health. Ultrasound is invaluable in The Evolution of Medical Imaging prenatal care, assessing cardiac function, and detecting abnormalities in organs such as the liver, kidneys, and The journey of medical imaging began with the discovery reproductive system. CT scans provide detailed cross- of X-rays by Wilhelm Conrad Roentgen in 1895. Since sectional images, aiding in the diagnosis of cancer, then, the field has experienced remarkable advancements, cardiovascular diseases, and neurological conditions. MRI with the development of technologies such as ultrasound, offers exceptional soft tissue contrast, making it particularly computed tomography (CT), magnetic resonance imaging valuable in diagnosing brain, spinal, and musculoskeletal (MRI), and nuclear medicine. Each imaging modality offers disorders. Nuclear medicine techniques, including positron unique capabilities and is used for specific diagnostic emission tomography (PET), enable the visualization of purposes, contributing to the comprehensive toolkit metabolic activity, aiding in the detection and staging of available to healthcare professionals. cancer, cardiac diseases, and neurological conditions. Advancements in Imaging Technology Challenges and Limitations In recent years, medical imaging technology has undergone While medical imaging has transformed healthcare, it is not significant advancements, revolutionizing the field. Digital without challenges and limitations. One significant concern imaging has replaced traditional film-based techniques, is the increasing demand for imaging services, leading to providing enhanced image quality, faster image acquisition, longer wait times and potential delays in diagnosis. and improved storage and accessibility of patient data. MAY, 2023 MAY, 2023 www.thecioworld.com www.thecioworld.com 24 25

  28. Limited access to imaging facilities, particularly in remote To Conclude, or underserved areas, poses another obstacle. Additionally, ensuring patient safety, minimizing radiation exposure, and The complex world of medical imaging holds immense managing the increasing volume of imaging data are significance in modern healthcare. From its humble ongoing challenges that require careful attention and beginnings to the current era of cutting-edge technology, innovative solutions. medical imaging has revolutionized diagnostics, treatment planning, and patient care. Advancements in imaging Global Perspectives on Medical Imaging technology, the wide range of applications, and ongoing research and innovation have propelled the field forward. Medical imaging practices vary across countries and healthcare systems globally. Developed nations often have However, challenges such as access, wait times, radiation well-established infrastructure, advanced imaging exposure, and resource disparities persist. It is crucial to technologies, and comprehensive quality control measures. address these challenges through collaborative efforts, In contrast, developing regions face resource constraints, technological advancements, and policy changes. limited access to advanced imaging modalities, and a Promoting equitable access to imaging services, enhancing training programs, and fostering international collaborations shortage of trained personnel. Efforts are underway to bridge these gaps through initiatives like telemedicine, are key steps in navigating the complex world of medical mobile imaging units, and training programs for healthcare imaging on a global scale. professionals. Collaborative partnerships between organizations, governments, and global health agencies are Moving forward, the future of medical imaging holds crucial for sharing expertise, knowledge, and resources to tremendous promise. Advancements in AI, machine improve access to medical imaging services worldwide. learning, and data analytics will further enhance image analysis, improve diagnostic accuracy, and expedite patient Research and Innovation care. Emerging technologies, such as molecular imaging and functional imaging, will unlock new possibilities in Medical imaging serves as a foundation for research and personalized medicine and targeted therapies. Ethical innovation in healthcare. The analysis of large datasets of considerations and patient-centered care must remain at the medical images allows researchers to identify patterns, forefront, ensuring the responsible and beneficial use of develop predictive models, and gain new insights into medical imaging technologies. disease mechanisms. Collaboration between imaging specialists, clinicians, and researchers is crucial for As healthcare continues to evolve, the global exploration of advancing the field and translating research findings into medical imaging will remain essential in transforming clinical practice. Furthermore, ongoing research aims to patient outcomes and shaping the future of healthcare develop novel imaging techniques, enhance imaging delivery. With continued dedication, collaboration, and protocols, and explore innovative applications in areas such innovation, we can navigate the complexities of medical as precision medicine and image-guided therapies. imaging and unlock its full potential in improving healthcare worldwide. Ethical Considerations and Patient-Centered Care As medical imaging continues to advance, ethical - P. D. Bombarde considerations and patient-centered care become increasingly important. Protecting patient privacy, ensuring informed consent, and maintaining data security are critical aspects of the provision and utilization of medical imaging. Additionally, maintaining a patient-centered approach involves effective communication with patients, addressing their concerns, and providing clear explanations about the imaging procedures and their implications. MAY, 2023 www.thecioworld.com 26

  29. Limited access to imaging facilities, particularly in remote To Conclude, or underserved areas, poses another obstacle. Additionally, ensuring patient safety, minimizing radiation exposure, and The complex world of medical imaging holds immense managing the increasing volume of imaging data are significance in modern healthcare. From its humble ongoing challenges that require careful attention and beginnings to the current era of cutting-edge technology, innovative solutions. medical imaging has revolutionized diagnostics, treatment planning, and patient care. Advancements in imaging Global Perspectives on Medical Imaging technology, the wide range of applications, and ongoing research and innovation have propelled the field forward. Medical imaging practices vary across countries and healthcare systems globally. Developed nations often have However, challenges such as access, wait times, radiation well-established infrastructure, advanced imaging exposure, and resource disparities persist. It is crucial to technologies, and comprehensive quality control measures. address these challenges through collaborative efforts, In contrast, developing regions face resource constraints, technological advancements, and policy changes. limited access to advanced imaging modalities, and a Promoting equitable access to imaging services, enhancing training programs, and fostering international collaborations shortage of trained personnel. Efforts are underway to bridge these gaps through initiatives like telemedicine, are key steps in navigating the complex world of medical mobile imaging units, and training programs for healthcare imaging on a global scale. professionals. Collaborative partnerships between organizations, governments, and global health agencies are Moving forward, the future of medical imaging holds crucial for sharing expertise, knowledge, and resources to tremendous promise. Advancements in AI, machine improve access to medical imaging services worldwide. learning, and data analytics will further enhance image analysis, improve diagnostic accuracy, and expedite patient Research and Innovation care. Emerging technologies, such as molecular imaging and functional imaging, will unlock new possibilities in Medical imaging serves as a foundation for research and personalized medicine and targeted therapies. Ethical innovation in healthcare. The analysis of large datasets of considerations and patient-centered care must remain at the medical images allows researchers to identify patterns, forefront, ensuring the responsible and beneficial use of develop predictive models, and gain new insights into medical imaging technologies. disease mechanisms. Collaboration between imaging specialists, clinicians, and researchers is crucial for As healthcare continues to evolve, the global exploration of advancing the field and translating research findings into medical imaging will remain essential in transforming clinical practice. Furthermore, ongoing research aims to patient outcomes and shaping the future of healthcare develop novel imaging techniques, enhance imaging delivery. With continued dedication, collaboration, and protocols, and explore innovative applications in areas such innovation, we can navigate the complexities of medical as precision medicine and image-guided therapies. imaging and unlock its full potential in improving healthcare worldwide. Ethical Considerations and Patient-Centered Care As medical imaging continues to advance, ethical - P. D. Bombarde considerations and patient-centered care become increasingly important. Protecting patient privacy, ensuring informed consent, and maintaining data security are critical aspects of the provision and utilization of medical imaging. Additionally, maintaining a patient-centered approach involves effective communication with patients, addressing their concerns, and providing clear explanations about the imaging procedures and their implications. MAY, 2023 www.thecioworld.com 26

  30. 10 Most Advanced Medical Imaging Solu?on Providers 2023 Deepak Behera The Versatile MD Leader Medical Imaging Consultancy Dr. Behera is a physician-scien?st turned execu?ve with more than 20 years of experience across the pharmaceu?cal Medical industry, health technologies, academia, and clinical health care fields. He began as a Nuclear Medicine physician and transi?oned into “bench-to-bedside” academic and scien?fic research at Stanford University. A?er that, he gained experience Consultancy in the industry of medical affairs and clinical Flourishing Healthcare with Exquisite Solu?ons development. He pairs his training as a physician with his ability to think as an academic, allowing Here are some of the highlights of the discussion: ringing new products and technologies to market in clients to receive expert knowledge in the healthcare field can be a challenging feat to clinical development & FDA interac?ons. Please brief our readers about Medical Imaging B manage, given the complexities of today’s global There are many facets to understanding Consultancy and kindly tell us the source of your market trends, cultural considerations, and need for value payer and clinical adop?ons, the logis?cs inspiration for venturing into the medical imaging driven solutions. unique to radiopharmaceu?cals, medical niche. affairs strategy, product launch, and A business’s need and vision, the impact on stakeholders, commercializa?on. I think clinical development, regulatory approval, and and marketplace forces, may need careful balancing. A market adoption of medical imaging products, especially symbiotic relationship among various stakeholders sought using radiopharmaceuticals, is a complex and niche These are all necessary components when and nurtured in a business venture allows not just co- environment. There are numerous and significant naviga?ng the complex existence, but also the synergistic possibility of untapped differences to be considered between this type of medicine radiopharmaceu?cal first-in-human to growth potential. and other pharma and device industries, including market pathway, and Dr. Behera excels at regulatory pathways, clinical study designs, business needs maneuvering through these nuances. In recent years, we have seen a paradigm shift in healthcare assessment, logistics, and scale of manufacturing and and new-gen technologies. This includes the rapidly supply chain, as well as eventual clinical market advancing area of radiopharmaceuticals and medical Dr. Behera enjoys the challenge of balancing positioning. imaging technologies. There is a high need and demand for the structured medical and regulatory partners with relevant expertise to support the incoming environments with the innova?ve realm of This can be daunting to understand and navigate, and new growth in this extremely specialized and niche area. crea?ng commercial value by iden?fying, entrants into this field often struggle to manage these defining, and ar?cula?ng the best product- complexities. Deepak Behera, MD at Medical Imaging Consultancy, market fits and establishing new clinical has set out to support this need by bringing together pathways via educa?onal marke?ng. At the same time, medical imaging and distinctive proficiencies towards development and radiopharmaceuticals are a rapidly growing field, and new commercialization of products and technologies in medical products addressing a multitude of clinical needs are imaging. constantly entering the market. There is a mismatch between innovators and people with relevant experience We discussed with Deepak Behera on his journey towards and understanding of the multiple aspects in this field founding Medical Imaging Consultancy, his core principles, necessary to take such products to market. and his views on the changing landscape of healthcare space in general. This was the inspiration for establishing Medical Imaging Consultancy, or MiC in short. MAY, 2023 www.thecioworld.com 28

  31. 10 Most Advanced Medical Imaging Solu?on Providers 2023 Deepak Behera The Versatile MD Leader Medical Imaging Consultancy Dr. Behera is a physician-scien?st turned execu?ve with more than 20 years of experience across the pharmaceu?cal Medical industry, health technologies, academia, and clinical health care fields. He began as a Nuclear Medicine physician and transi?oned into “bench-to-bedside” academic and scien?fic research at Stanford University. A?er that, he gained experience Consultancy in the industry of medical affairs and clinical Flourishing Healthcare with Exquisite Solu?ons development. He pairs his training as a physician with his ability to think as an academic, allowing Here are some of the highlights of the discussion: ringing new products and technologies to market in clients to receive expert knowledge in the healthcare field can be a challenging feat to clinical development & FDA interac?ons. Please brief our readers about Medical Imaging B manage, given the complexities of today’s global There are many facets to understanding Consultancy and kindly tell us the source of your market trends, cultural considerations, and need for value payer and clinical adop?ons, the logis?cs inspiration for venturing into the medical imaging driven solutions. unique to radiopharmaceu?cals, medical niche. affairs strategy, product launch, and A business’s need and vision, the impact on stakeholders, commercializa?on. I think clinical development, regulatory approval, and and marketplace forces, may need careful balancing. A market adoption of medical imaging products, especially symbiotic relationship among various stakeholders sought using radiopharmaceuticals, is a complex and niche These are all necessary components when and nurtured in a business venture allows not just co- environment. There are numerous and significant naviga?ng the complex existence, but also the synergistic possibility of untapped differences to be considered between this type of medicine radiopharmaceu?cal first-in-human to growth potential. and other pharma and device industries, including market pathway, and Dr. Behera excels at regulatory pathways, clinical study designs, business needs maneuvering through these nuances. In recent years, we have seen a paradigm shift in healthcare assessment, logistics, and scale of manufacturing and and new-gen technologies. This includes the rapidly supply chain, as well as eventual clinical market advancing area of radiopharmaceuticals and medical Dr. Behera enjoys the challenge of balancing positioning. imaging technologies. There is a high need and demand for the structured medical and regulatory partners with relevant expertise to support the incoming environments with the innova?ve realm of This can be daunting to understand and navigate, and new growth in this extremely specialized and niche area. crea?ng commercial value by iden?fying, entrants into this field often struggle to manage these defining, and ar?cula?ng the best product- complexities. Deepak Behera, MD at Medical Imaging Consultancy, market fits and establishing new clinical has set out to support this need by bringing together pathways via educa?onal marke?ng. At the same time, medical imaging and distinctive proficiencies towards development and radiopharmaceuticals are a rapidly growing field, and new commercialization of products and technologies in medical products addressing a multitude of clinical needs are imaging. constantly entering the market. There is a mismatch between innovators and people with relevant experience We discussed with Deepak Behera on his journey towards and understanding of the multiple aspects in this field founding Medical Imaging Consultancy, his core principles, necessary to take such products to market. and his views on the changing landscape of healthcare space in general. This was the inspiration for establishing Medical Imaging Consultancy, or MiC in short. MAY, 2023 www.thecioworld.com 28

  32. Technology evaluation for investment and business achieve; two, realize that it takes a village to accomplish MiC’s goal is to become an extension of our client’s team, decisions. anything related to medical imaging. Engaging the people get in their shoes, and endeavor toward our mutual success. • Clinical support for intellectual property creation. with the right skill-set to achieve their goals will be the key to success. Given the nature of industry needs, this is much better What is your opinion on healthcare providers’ aligning appreciated by our partners and clients as opposed to a their offerings with newer technological developments, We always encourage new ideas because those will transactional model, where service providers are recruited If we do good, especially when it comes to catering to the dynamic ultimately be the future. Big things always start small, and and paid for specific deliverables without a solid attachment good will come needs of the healthcare space? we aim to help turn those ideas into reality. to the client’s problems and overall vision and strategy. How do you envision scaling Medical Imaging Healthcare is in a major evolutionary re-vamp right now. Our belief is that if we do good, good will come to us. Consultancy in 2023 and beyond? We have seen a dynamic shift in the practice and to us.,,,, management of healthcare over the last few years due to Kindly elaborate upon the services that make Medical COVID-19. This has created the need for a more fluid Our offering is our personnel and subject matter expertise. Imaging Consultancy stand out from the competition. healthcare space, which requires integrated and patient- We plan to expand by bringing on more expert consultants focused technology to be developed. What makes us stand out is our ability to bring synergy My team and I set out to solve this need by using our as well as our footprint on social media and continue our from various fields and interest in the success of our clients existing and growing knowledge of this industry and Healthcare is currently undergoing the transformation that participation in networking events, thus allowing us to as opposed to simply completing a project or getting further partnering with early to mid-stage pharma, biotech, and transportation went from a ‘taxi only’ to a co-existing ‘taxi expand our community of partners and product placement business. device companies to provide strategic and operational & Uber’ or vacationing went from a ‘hotel only’ to a co- experts. advice related to radiopharmaceutical and medical imaging existing ‘hotel & AirBnB’ stage. Our organization comprises experts in research products. We are committed to continuous learning so that we can development, medical affairs, clinical trial design and Healthcare is rapidly adopting a hybrid old-school clinic bring new ideas to the table for our clients. Individuals support, and regulatory strategy. We are committed to In addition to having an in-house knowledge base, MiC also plus telemedicine scenario. interested in learning more and becoming a part of Medical helping businesses design thoughtful and successful leverages a network of adjacent service providers in Imaging Consultancy are always welcome for a chat over a development & marketing plans to minimize time and cost. marketing, payer engagement, regulatory operations, In addition, the traditionally closed and siloed healthcare cup of coffee. clinical operations, chemistry, physics, statistics, medical environment is opening up to myriads of possibilities by At the same time, maximize efforts for product positioning writing, dosimetry, CROs, clinical trial sites, etc. to fill gaps beginning to allow data from various silos to interact with for marketing, development, and investment potential. and needs for our partners. each other. The potential for data science, machine learning, and even artificial intelligence to impact healthcare is MiC offers a wide range of services, including: Over the years, MiC has built fundamental relationships enormous at both individual and population levels. with major manufacturers and suppliers of • Clinical development strategy and planning. radiopharmaceuticals and imaging products, most major We are re-training ourselves on what the healthcare model • Regulatory support in clinical questions and decisions, universities and academic centers in the US, as well as a should look like, and this is a great place to be for the including FDA interactions. vast number of community radiologists and nuclear growth and development of new ideas and tools which will • Clinical trial design, including image analysis medicine physicians. We are able to strategically utilize this improve the practice of medicine. strategies. network to prepare for launching products onto the market. • Clinical/Medical executive representative for sponsor. We offer our clients a variety of services such as clinical Need drives change, which is often the most challenging (e.g., fractional CMO roles) development strategy and planning, a customized strategy roadblock regarding new product design and integration. • Medical/clinical support for clinical operations – plan, product-market analysis, commercialization, and The need is here, and we are committed to helping to bring drafting and reviewing of clinical trial protocols and product launch activities. the change. other study documents, reviewing the interpretation of clinical trial data, site visits for training and education. Can you elaborate upon the core values on which What advice would you like to give to the budding • US representative for non-US companies. Medical Imaging Consultancy is built and its mission? entrepreneurs and enthusiasts aspiring to venture into • Medical advice, strategy, and management for the medical imaging niche you are catering to? investigator-sponsored studies. The goal of Medical Imaging Consultancy is to nudge • Medical monitoring and consulting for healthcare towards a better patient outcome while There is a significant need in the medical imaging and pharmacovigilance, including being client’s medical generating value along the way for all stakeholders. radiopharmaceutical development area. We wholeheartedly safety officer. welcome more interest in this area. This is a multi-specialty, • Clinical/scientific support for business development My team and I aim to be the support information system multi-dimensional area in need of very many skill-sets. activities and strategic collaborations. companies need to launch them towards future growth and • Product launch and post-marketing medical affairs, success. We are vested in our client’s success, and our My advice to entrepreneurs venturing into this will be two- including development reader training programs, mission is to guide them to a place where they have the fold: one, identify and understand what they want to training, and educational materials for field personnel. tools and knowledge to operate self-sufficiently. MAY, 2023 MAY, 2023 www.thecioworld.com www.thecioworld.com 30 31

  33. Technology evaluation for investment and business achieve; two, realize that it takes a village to accomplish MiC’s goal is to become an extension of our client’s team, decisions. anything related to medical imaging. Engaging the people get in their shoes, and endeavor toward our mutual success. • Clinical support for intellectual property creation. with the right skill-set to achieve their goals will be the key to success. Given the nature of industry needs, this is much better What is your opinion on healthcare providers’ aligning appreciated by our partners and clients as opposed to a their offerings with newer technological developments, We always encourage new ideas because those will transactional model, where service providers are recruited If we do good, especially when it comes to catering to the dynamic ultimately be the future. Big things always start small, and and paid for specific deliverables without a solid attachment good will come needs of the healthcare space? we aim to help turn those ideas into reality. to the client’s problems and overall vision and strategy. How do you envision scaling Medical Imaging Healthcare is in a major evolutionary re-vamp right now. Our belief is that if we do good, good will come to us. Consultancy in 2023 and beyond? We have seen a dynamic shift in the practice and to us.,,,, management of healthcare over the last few years due to Kindly elaborate upon the services that make Medical COVID-19. This has created the need for a more fluid Our offering is our personnel and subject matter expertise. Imaging Consultancy stand out from the competition. healthcare space, which requires integrated and patient- We plan to expand by bringing on more expert consultants focused technology to be developed. What makes us stand out is our ability to bring synergy My team and I set out to solve this need by using our as well as our footprint on social media and continue our from various fields and interest in the success of our clients existing and growing knowledge of this industry and Healthcare is currently undergoing the transformation that participation in networking events, thus allowing us to as opposed to simply completing a project or getting further partnering with early to mid-stage pharma, biotech, and transportation went from a ‘taxi only’ to a co-existing ‘taxi expand our community of partners and product placement business. device companies to provide strategic and operational & Uber’ or vacationing went from a ‘hotel only’ to a co- experts. advice related to radiopharmaceutical and medical imaging existing ‘hotel & AirBnB’ stage. Our organization comprises experts in research products. We are committed to continuous learning so that we can development, medical affairs, clinical trial design and Healthcare is rapidly adopting a hybrid old-school clinic bring new ideas to the table for our clients. Individuals support, and regulatory strategy. We are committed to In addition to having an in-house knowledge base, MiC also plus telemedicine scenario. interested in learning more and becoming a part of Medical helping businesses design thoughtful and successful leverages a network of adjacent service providers in Imaging Consultancy are always welcome for a chat over a development & marketing plans to minimize time and cost. marketing, payer engagement, regulatory operations, In addition, the traditionally closed and siloed healthcare cup of coffee. clinical operations, chemistry, physics, statistics, medical environment is opening up to myriads of possibilities by At the same time, maximize efforts for product positioning writing, dosimetry, CROs, clinical trial sites, etc. to fill gaps beginning to allow data from various silos to interact with for marketing, development, and investment potential. and needs for our partners. each other. The potential for data science, machine learning, and even artificial intelligence to impact healthcare is MiC offers a wide range of services, including: Over the years, MiC has built fundamental relationships enormous at both individual and population levels. with major manufacturers and suppliers of • Clinical development strategy and planning. radiopharmaceuticals and imaging products, most major We are re-training ourselves on what the healthcare model • Regulatory support in clinical questions and decisions, universities and academic centers in the US, as well as a should look like, and this is a great place to be for the including FDA interactions. vast number of community radiologists and nuclear growth and development of new ideas and tools which will • Clinical trial design, including image analysis medicine physicians. We are able to strategically utilize this improve the practice of medicine. strategies. network to prepare for launching products onto the market. • Clinical/Medical executive representative for sponsor. We offer our clients a variety of services such as clinical Need drives change, which is often the most challenging (e.g., fractional CMO roles) development strategy and planning, a customized strategy roadblock regarding new product design and integration. • Medical/clinical support for clinical operations – plan, product-market analysis, commercialization, and The need is here, and we are committed to helping to bring drafting and reviewing of clinical trial protocols and product launch activities. the change. other study documents, reviewing the interpretation of clinical trial data, site visits for training and education. Can you elaborate upon the core values on which What advice would you like to give to the budding • US representative for non-US companies. Medical Imaging Consultancy is built and its mission? entrepreneurs and enthusiasts aspiring to venture into • Medical advice, strategy, and management for the medical imaging niche you are catering to? investigator-sponsored studies. The goal of Medical Imaging Consultancy is to nudge • Medical monitoring and consulting for healthcare towards a better patient outcome while There is a significant need in the medical imaging and pharmacovigilance, including being client’s medical generating value along the way for all stakeholders. radiopharmaceutical development area. We wholeheartedly safety officer. welcome more interest in this area. This is a multi-specialty, • Clinical/scientific support for business development My team and I aim to be the support information system multi-dimensional area in need of very many skill-sets. activities and strategic collaborations. companies need to launch them towards future growth and • Product launch and post-marketing medical affairs, success. We are vested in our client’s success, and our My advice to entrepreneurs venturing into this will be two- including development reader training programs, mission is to guide them to a place where they have the fold: one, identify and understand what they want to training, and educational materials for field personnel. tools and knowledge to operate self-sufficiently. MAY, 2023 MAY, 2023 www.thecioworld.com www.thecioworld.com 30 31

  34. Demystifying Advancements emit gamma rays to detect metabolic and molecular activity within the body. Applications in Diagnostics Understanding the Advanced imaging technologies have significantly improved the accuracy and speed of diagnoses across Technology and various medical specialties. In radiology, advanced imaging plays a crucial role in the detection and characterization of tumors, identification of abnormalities in the cardiovascular Applications of system, evaluation of musculoskeletal injuries, and assessment of brain disorders. In cardiology, advanced imaging techniques aid in the diagnosis of heart diseases, Advanced Imaging evaluation of blood flow, and assessment of cardiac function. Additionally, advanced imaging is invaluable in oncology for staging tumors, monitoring treatment response, and guiding surgical interventions. Advancements in Image-Guided Interventions Advanced imaging has also transformed the field of image- guided interventions, where medical procedures are performed with real-time imaging guidance. Techniques such as interventional radiology, image-guided surgery, and dvanced imaging technologies have minimally invasive procedures rely on advanced imaging revolutionized the field of healthcare, enabling technologies to precisely target and treat specific areas of healthcare professionals to visualize and the body. These advancements have led to shorter procedure diagnose medical conditions with times, reduced invasiveness, improved patient outcomes, A unprecedented detail and accuracy. and faster recovery. Further, we delve into the intricacies of advanced imaging, Innovations in Artificial Intelligence exploring the technology behind it and the wide range of applications that benefit patients and healthcare providers! Artificial intelligence (AI) has emerged as a powerful tool in advanced imaging, revolutionizing image analysis and The Technology Behind Advanced Imaging interpretation. AI algorithms can analyze large datasets of medical images, identify patterns, and assist healthcare Advanced imaging encompasses a variety of technologies, professionals in diagnosing diseases. For example, AI each offering unique capabilities for capturing and algorithms can aid radiologists in detecting subtle interpreting medical images. These technologies include abnormalities in mammograms for early breast cancer magnetic resonance imaging (MRI), computed tomography detection or assist in the detection of lung nodules on CT (CT), positron emission tomography (PET), and single- scans. AI-powered software can also help radiologists photon emission computed tomography (SPECT). Each prioritize urgent cases, streamline workflow, and improve imaging modality utilizes different principles and equipment diagnostic accuracy. to generate detailed images of the human body. Challenges and Considerations MRI relies on powerful magnets and radio waves to create detailed images of soft tissues, organs, and internal While advanced imaging technologies offer numerous structures. CT scans utilize a combination of X-rays and benefits, they also present challenges and considerations. computer algorithms to produce cross-sectional images of Accessibility and affordability of advanced imaging can the body. PET and SPECT employ radioactive tracers that vary, especially in resource-limited settings. MAY, 2023 MAY, 2023 www.thecioworld.com www.thecioworld.com 32 33

  35. Demystifying Advancements emit gamma rays to detect metabolic and molecular activity within the body. Applications in Diagnostics Understanding the Advanced imaging technologies have significantly improved the accuracy and speed of diagnoses across Technology and various medical specialties. In radiology, advanced imaging plays a crucial role in the detection and characterization of tumors, identification of abnormalities in the cardiovascular Applications of system, evaluation of musculoskeletal injuries, and assessment of brain disorders. In cardiology, advanced imaging techniques aid in the diagnosis of heart diseases, Advanced Imaging evaluation of blood flow, and assessment of cardiac function. Additionally, advanced imaging is invaluable in oncology for staging tumors, monitoring treatment response, and guiding surgical interventions. Advancements in Image-Guided Interventions Advanced imaging has also transformed the field of image- guided interventions, where medical procedures are performed with real-time imaging guidance. Techniques such as interventional radiology, image-guided surgery, and dvanced imaging technologies have minimally invasive procedures rely on advanced imaging revolutionized the field of healthcare, enabling technologies to precisely target and treat specific areas of healthcare professionals to visualize and the body. These advancements have led to shorter procedure diagnose medical conditions with times, reduced invasiveness, improved patient outcomes, A unprecedented detail and accuracy. and faster recovery. Further, we delve into the intricacies of advanced imaging, Innovations in Artificial Intelligence exploring the technology behind it and the wide range of applications that benefit patients and healthcare providers! Artificial intelligence (AI) has emerged as a powerful tool in advanced imaging, revolutionizing image analysis and The Technology Behind Advanced Imaging interpretation. AI algorithms can analyze large datasets of medical images, identify patterns, and assist healthcare Advanced imaging encompasses a variety of technologies, professionals in diagnosing diseases. For example, AI each offering unique capabilities for capturing and algorithms can aid radiologists in detecting subtle interpreting medical images. These technologies include abnormalities in mammograms for early breast cancer magnetic resonance imaging (MRI), computed tomography detection or assist in the detection of lung nodules on CT (CT), positron emission tomography (PET), and single- scans. AI-powered software can also help radiologists photon emission computed tomography (SPECT). Each prioritize urgent cases, streamline workflow, and improve imaging modality utilizes different principles and equipment diagnostic accuracy. to generate detailed images of the human body. Challenges and Considerations MRI relies on powerful magnets and radio waves to create detailed images of soft tissues, organs, and internal While advanced imaging technologies offer numerous structures. CT scans utilize a combination of X-rays and benefits, they also present challenges and considerations. computer algorithms to produce cross-sectional images of Accessibility and affordability of advanced imaging can the body. PET and SPECT employ radioactive tracers that vary, especially in resource-limited settings. MAY, 2023 MAY, 2023 www.thecioworld.com www.thecioworld.com 32 33

  36. Maintenance and operational costs of imaging equipment particularly in underserved areas, will help ensure that can be significant, requiring healthcare institutions to patients around the world can benefit from these life-saving carefully manage their resources. Additionally, patient advancements. safety, radiation exposure, and the ethical use of patient data are critical concerns that must be addressed. As we navigate the complex world of advanced imaging, it is crucial to prioritize patient safety, data security, and Future Directions and Possibilities ethical considerations. Striking a balance between technological advancements and patient-centered care will The future of advanced imaging holds tremendous promise. be key to delivering the best possible outcomes for Ongoing research aims to enhance the speed and resolution individuals. of imaging techniques, develop novel contrast agents, and refine image reconstruction algorithms. Furthermore, advancements in hybrid imaging, combining multiple - P. D. Bombarde imaging modalities, may lead to even more precise and comprehensive diagnostic capabilities. Integration with other technologies, such as robotics and virtual reality, may further enhance surgical interventions and training. To Conclude, Advanced imaging technologies have become invaluable tools in modern healthcare, empowering healthcare professionals to provide accurate diagnoses, guide interventions, and improve patient outcomes. Understanding the technology behind advanced imaging and its vast applications is essential for healthcare providers and patients alike. As advancements continue, it is crucial to address challenges, promote accessibility, and ensure the responsible use of advanced imaging technologies. With ongoing research, we can expect even more remarkable developments in the field of advanced imaging. The integration of artificial intelligence and machine learning will further enhance image analysis and interpretation, leading to more precise and efficient diagnoses. Moreover, advancements in imaging technology will likely result in improved image quality, faster acquisition times, and reduced radiation exposure for patients. To fully harness the potential of advanced imaging, collaboration between researchers, healthcare professionals, and technology developers is vital. By working together, they can address challenges, share knowledge, and drive innovation in the field. Additionally, ongoing efforts to improve access to advanced imaging technologies, MAY, 2023 www.thecioworld.com 34

  37. Maintenance and operational costs of imaging equipment particularly in underserved areas, will help ensure that can be significant, requiring healthcare institutions to patients around the world can benefit from these life-saving carefully manage their resources. Additionally, patient advancements. safety, radiation exposure, and the ethical use of patient data are critical concerns that must be addressed. As we navigate the complex world of advanced imaging, it is crucial to prioritize patient safety, data security, and Future Directions and Possibilities ethical considerations. Striking a balance between technological advancements and patient-centered care will The future of advanced imaging holds tremendous promise. be key to delivering the best possible outcomes for Ongoing research aims to enhance the speed and resolution individuals. of imaging techniques, develop novel contrast agents, and refine image reconstruction algorithms. Furthermore, advancements in hybrid imaging, combining multiple - P. D. Bombarde imaging modalities, may lead to even more precise and comprehensive diagnostic capabilities. Integration with other technologies, such as robotics and virtual reality, may further enhance surgical interventions and training. To Conclude, Advanced imaging technologies have become invaluable tools in modern healthcare, empowering healthcare professionals to provide accurate diagnoses, guide interventions, and improve patient outcomes. Understanding the technology behind advanced imaging and its vast applications is essential for healthcare providers and patients alike. As advancements continue, it is crucial to address challenges, promote accessibility, and ensure the responsible use of advanced imaging technologies. With ongoing research, we can expect even more remarkable developments in the field of advanced imaging. The integration of artificial intelligence and machine learning will further enhance image analysis and interpretation, leading to more precise and efficient diagnoses. Moreover, advancements in imaging technology will likely result in improved image quality, faster acquisition times, and reduced radiation exposure for patients. To fully harness the potential of advanced imaging, collaboration between researchers, healthcare professionals, and technology developers is vital. By working together, they can address challenges, share knowledge, and drive innovation in the field. Additionally, ongoing efforts to improve access to advanced imaging technologies, MAY, 2023 www.thecioworld.com 34

  38. An Adept Leadership An Anecdote of Health, Hope, and Healing! Seasoned business leader Jon DeVries joined Mirada Medical as CEO in September 2021. DeVries is a renowned tech visionary known for advancing ar?ficial cience and society have always been working in intelligence (AI) adop?on in We are at a key stage in tandem. Be it the ever-evolving technological healthcare and commercializing S transformation, rediscovering algorithms, or Mirada's evolution with some medical imaging solu?ons. transgressing software advantages for diagnostics segments new solutions and partnerships of healthcare, the scientific inventions have been in development that will once Since joining Mirada Medical, Jon transforming society for the better. again see Mirada break ground has sort to comprehended the world-leading scien?fic, so?ware, in a new category. Understanding this bridging role of technology that and medical capabili?es of the integrates science with society, it is important to scout, organiza?on and focused them on learn and acknowledge the hustles of healthcare disruptors clear areas of cancer care where Jon, please enlighten us about Mirada Medical and who are paving the way for the next generational it can deliver the most value. kindly tell us about your source of inspiration for innovations in the diagnostics segment, specifically in the Having already established the AI- venturing into the medical imaging niche. radiology niche. Autocontouring category in cancer care, Jon's work paves the Mirada is a world leader in software for quantitative image And, if one scouts around the modern trends of diagnostics way for Mirada to deliver analysis and disease characterization used to diagnose marvel, it is hardly possible to be inconsiderate towards transforma?onal innova?on in cancer and guide the delivery of radiation-based treatments. medical imaging solution providers. Instigated with such exci?ng new areas of cancer care. Mirada's software is currently used in over 2,000 hospitals mindboggling thought, we at The CIO World investigated globally and sold directly to hospitals as well as through around the globe and dropped by one of the leading strategic partnerships with the world's leading imaging and imaging and radiotherapy companies. Known for its agile Jon DeVries radiotherapy companies, including GE, Boston Scientific, development and trustworthy approach is Mirada Medical. CEO Canon, Philips, Varian, and Change Healthcare. Mirada Medical As a leading platform for the powerful image registration, visualization, and contour editing software, Mirada exemplifies the true meaning of technology leadership while twirling the wind and ensuring that every cancer patient finds hope in the healthcare community. Can you elaborate upon the core values on which Kindly elaborate upon the services that positioned Standing at the helm of this transformation is its Chief Mirada Medical is built, what is its mission and vision Mirada Medical as one of the advanced medical imaging Executive Officer,Jon DeVries, an influential leader for for the modern healthcare industry? solution providers in the healthcare industry. the Miradaites. He is an expert in world-leading medical software systems, and since he joined Mirada, he has been Our purpose is to accelerate cancer care. We believe that by Mirada's leadership and innovation are founded on its dedicated to delivering transformative innovation in the making cancer care universally available, free of delays, scientific credentials and proactive willingness to work with cancer care segment. and equipped to use the latest techniques, we can improve industry partners. Solutions, such as RTx, Mirada's patient outcomes and experience. Medical imaging sits at powerful image registration, visualization, and contour To know more about the Mirada and its executive leader- the heart of this, and through our scientific advancement, editing software, are so well respected that when GE Jon DeVries, explore the further excerpts from the interview! technical innovation, and clinical expertise we deliver Healthcare sort of enhancing their own cancer visualization solutions that personalize image-guided cancer treatment and diagnostic capabilities, they integrate it fully into their and help clinicians achieve this goal. solutions. Equally, this 'Mirada Inside' approach sees its MAY, 2023 MAY, 2023 www.thecioworld.com www.thecioworld.com 36 37

  39. An Adept Leadership An Anecdote of Health, Hope, and Healing! Seasoned business leader Jon DeVries joined Mirada Medical as CEO in September 2021. DeVries is a renowned tech visionary known for advancing ar?ficial cience and society have always been working in intelligence (AI) adop?on in We are at a key stage in tandem. Be it the ever-evolving technological healthcare and commercializing S transformation, rediscovering algorithms, or Mirada's evolution with some medical imaging solu?ons. transgressing software advantages for diagnostics segments new solutions and partnerships of healthcare, the scientific inventions have been in development that will once Since joining Mirada Medical, Jon transforming society for the better. again see Mirada break ground has sort to comprehended the world-leading scien?fic, so?ware, in a new category. Understanding this bridging role of technology that and medical capabili?es of the integrates science with society, it is important to scout, organiza?on and focused them on learn and acknowledge the hustles of healthcare disruptors clear areas of cancer care where Jon, please enlighten us about Mirada Medical and who are paving the way for the next generational it can deliver the most value. kindly tell us about your source of inspiration for innovations in the diagnostics segment, specifically in the Having already established the AI- venturing into the medical imaging niche. radiology niche. Autocontouring category in cancer care, Jon's work paves the Mirada is a world leader in software for quantitative image And, if one scouts around the modern trends of diagnostics way for Mirada to deliver analysis and disease characterization used to diagnose marvel, it is hardly possible to be inconsiderate towards transforma?onal innova?on in cancer and guide the delivery of radiation-based treatments. medical imaging solution providers. Instigated with such exci?ng new areas of cancer care. Mirada's software is currently used in over 2,000 hospitals mindboggling thought, we at The CIO World investigated globally and sold directly to hospitals as well as through around the globe and dropped by one of the leading strategic partnerships with the world's leading imaging and imaging and radiotherapy companies. Known for its agile Jon DeVries radiotherapy companies, including GE, Boston Scientific, development and trustworthy approach is Mirada Medical. CEO Canon, Philips, Varian, and Change Healthcare. Mirada Medical As a leading platform for the powerful image registration, visualization, and contour editing software, Mirada exemplifies the true meaning of technology leadership while twirling the wind and ensuring that every cancer patient finds hope in the healthcare community. Can you elaborate upon the core values on which Kindly elaborate upon the services that positioned Standing at the helm of this transformation is its Chief Mirada Medical is built, what is its mission and vision Mirada Medical as one of the advanced medical imaging Executive Officer,Jon DeVries, an influential leader for for the modern healthcare industry? solution providers in the healthcare industry. the Miradaites. He is an expert in world-leading medical software systems, and since he joined Mirada, he has been Our purpose is to accelerate cancer care. We believe that by Mirada's leadership and innovation are founded on its dedicated to delivering transformative innovation in the making cancer care universally available, free of delays, scientific credentials and proactive willingness to work with cancer care segment. and equipped to use the latest techniques, we can improve industry partners. Solutions, such as RTx, Mirada's patient outcomes and experience. Medical imaging sits at powerful image registration, visualization, and contour To know more about the Mirada and its executive leader- the heart of this, and through our scientific advancement, editing software, are so well respected that when GE Jon DeVries, explore the further excerpts from the interview! technical innovation, and clinical expertise we deliver Healthcare sort of enhancing their own cancer visualization solutions that personalize image-guided cancer treatment and diagnostic capabilities, they integrate it fully into their and help clinicians achieve this goal. solutions. Equally, this 'Mirada Inside' approach sees its MAY, 2023 MAY, 2023 www.thecioworld.com www.thecioworld.com 36 37

  40. What advice would you like to give to the budding entrepreneurs and enthusiasts aspiring to venture into the medical imaging niche? Have a focus and purpose that puts the patient at the heart of everything that you do. You may never engage directly with a patient, but through your service or your partner's, patient outcomes should drive everything that you do. How do you envision scaling Mirada Medical's services and operations in 2023 and beyond? We are at a key stage in Mirada's evolution with some new solutions and partnerships in development that will once again see Mirada break ground in a new category. We're tremendously excited, but I'm afraid that launch announcements will come later in the year. So, watch this space. Please give us a few testimonials from your clients and awards or recognition that accurately highlight your organization's position in the market. ''Mirada RTx has become an indispensable part of the treatment preparation workflow in our clinic. The software provides us with a ton of options for image registration and contouring in a user-friendly environment that enables you to generate your own layouts and macros. Mirada employees are very communicative and helpful, offering support via online meetings when necessary. During live technologies integrated into solutions offered by industry visits, they dive into our clinical workflows to be able to heavyweights such as Canon, Reflexion, SORNA, and adapt the software to our specific needs.'' Boston Scientific. Ÿ Ellen Brunenberg, Medical Physicist, Department of What is your opinion on healthcare providers' aligning Radiation Oncology, Radboudumc, Nijmegen, The their offerings with newer technological developments, Netherland especially when it comes to catering to the ever-evolving needs of the healthcare sector? ''The Mirada application has exceeded my expectations. XD is so much better than anything I've read on before.'' Healthcare providers have always had to innovate their offerings and stay in touch with developments, in order to Ÿ Phillip Kuo, MD, PhD, Professor, Medical Imaging, improve patient outcomes. The challenge today is the University Medical Center Tucson, AZ phenomenal pace of change that clinics have to contend with and the sophisticating demands of the patient. Healthcare providers need to be agile and equipped to move quickly to evaluate and adopt the latest technologies. At the same time, vendors like Mirada need to bring to market solutions that can be seamlessly integrated into workflows with zero to minimal impact on the operations of the clinic. MAY, 2023 www.thecioworld.com 38

  41. What advice would you like to give to the budding entrepreneurs and enthusiasts aspiring to venture into the medical imaging niche? Have a focus and purpose that puts the patient at the heart of everything that you do. You may never engage directly with a patient, but through your service or your partner's, patient outcomes should drive everything that you do. How do you envision scaling Mirada Medical's services and operations in 2023 and beyond? We are at a key stage in Mirada's evolution with some new solutions and partnerships in development that will once again see Mirada break ground in a new category. We're tremendously excited, but I'm afraid that launch announcements will come later in the year. So, watch this space. Please give us a few testimonials from your clients and awards or recognition that accurately highlight your organization's position in the market. ''Mirada RTx has become an indispensable part of the treatment preparation workflow in our clinic. The software provides us with a ton of options for image registration and contouring in a user-friendly environment that enables you to generate your own layouts and macros. Mirada employees are very communicative and helpful, offering support via online meetings when necessary. During live technologies integrated into solutions offered by industry visits, they dive into our clinical workflows to be able to heavyweights such as Canon, Reflexion, SORNA, and adapt the software to our specific needs.'' Boston Scientific. Ÿ Ellen Brunenberg, Medical Physicist, Department of What is your opinion on healthcare providers' aligning Radiation Oncology, Radboudumc, Nijmegen, The their offerings with newer technological developments, Netherland especially when it comes to catering to the ever-evolving needs of the healthcare sector? ''The Mirada application has exceeded my expectations. XD is so much better than anything I've read on before.'' Healthcare providers have always had to innovate their offerings and stay in touch with developments, in order to Ÿ Phillip Kuo, MD, PhD, Professor, Medical Imaging, improve patient outcomes. The challenge today is the University Medical Center Tucson, AZ phenomenal pace of change that clinics have to contend with and the sophisticating demands of the patient. Healthcare providers need to be agile and equipped to move quickly to evaluate and adopt the latest technologies. At the same time, vendors like Mirada need to bring to market solutions that can be seamlessly integrated into workflows with zero to minimal impact on the operations of the clinic. MAY, 2023 www.thecioworld.com 38

  42. THE CI INSPIRING THE BUSINESS WORLD www.thecioworld.com

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