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Tadalista 40 mg is also used to treat the indications of an enlarged prostate (benign prostatic hyperplasia-BPH). It helps to reduce symptoms of BPH such as difficulty in starting the flow of urine, weak stream, and the need to sweat frequently or anxious (including during the thick of the night). Tadalafil 40 is thought to work by relaxing the smooth meat in the prostate and bladder.