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6. What Is MTP Kit? MTP Kit (Medical Termination of Pregnancy Kit)is a combination of two drugs used and applied to induce medication abortion. These drugs are Misoprostol Pills and Mifepristone Pills. This is a set of two medicines especially used for medical abortion/termination of intrauterine pregnancy up to 63 days of fertilization. http://www.usmedskart.com +1 (844) 257 2665

7. Why Medical Termination Of Pregnancy? Pregnancy is a highly sensitive issue. Parents have to be prepared for it in many ways. Pregnancy and subsequent childbirth, raising a family demands huge financial, physical, mental and psychological resources. The role of woman is more critical here. She sacrifices almost everything to become a mother. She sacrifices her job, career, and health, even herself for this reason. So if for certain reasons the parents or the pregnant woman is not prepared for childbirth, medical termination of pregnancy remains a scientific, medical solution. There are many legal and medical reasons those may also require termination of unwanted pregnancy. A forced rape resulting into a undesirable pregnancy or any fatal untreatable genetic disease that may carry to the fetus also demands a safe and secured medical termination of that pregnancy. Medical Termination of Pregnancy Kit is highly sensitive product and must be used under extreme discretion, with legal permission and most importantly, under the observation of a specialist doctor. http://www.usmedskart.com +1 (844) 257 2665

8. What Is The Composition Of MTP Kit? Each kit contains 5 tablets of- • 1 Mifepristone tablet- 200 mg. • 4 Misoprostol tablets- 200 mcg. How to administer MTP Kit? Mifepristone tablet in the MTP Kit is to be taken orally and Misoprostol tablets are to be administered through vaginal route. http://www.usmedskart.com +1 (844) 257 2665

9. Doses of MTP kit? The dosage is Mifepristone 200 mg orally followed 1 - 3 days later by Misoprostol 800 mcg, 4 tablets of 200 mcg, vaginally. The Misoprostol may be administered by a health care provider or self-administered by the woman. For women at 49 - 63 days of gestation, if abortion has not occurred 4 hours after administration of Misoprostol, a second dose of Misoprostol 400 mcg ,2 tablets of 200 mcg may be administered vaginally or orally, depending upon preference and amount of bleeding. http://www.usmedskart.com +1 (844) 257 2665

10. Working Mechanism of MTP Kit Mifepristone Pills:- Mifepristone is a synthetic steroid with an anti-progestational action as a result of competition with progesterone at the progesterone receptors. This results in termination of pregnancy. Mifepristone antagonizes the endometrial and myometrial effects of progesterone. During pregnancy, it sensitizes the myometrium to the contraction - inducing action of prostaglandin. During the first trimester, pre-treatment with Mifepristone allows the dilatation and opening of the cervix uteri. MisoprostolPills:- Misoprostol is a synthetic prostaglandin E1 which is a potent inhibitor of gastric acid secretion in humans. It also causes the cervix to soften and the uterus to contract. Prostaglandin E1 causes myometrial contractions by interacting with specific receptors on myometrial cells. This interaction results in a change in calcium concentration, thereby initiating muscle contraction. By interacting with prostaglandin receptors, Misoprostol causes the cervix to soften and the uterus to contract, resulting in the expulsion of the uterine contents. http://www.usmedskart.com +1 (844) 257 2665

11. Precaution with use of MTP Kit The patient should return for a follow-up visit approximately 14 days after the administration of Mifepristone. This visit is very important to confirm by clinical examination or ultrasonography scan that a complete termination of pregnancy has occurred. A follow-up visit must take place within a period of 14 - 21 days after administration of Mifepristone to verify by the appropriate means, clinical examination, ultrasound scan, and beta-HCG measurement that expulsion has been completed and that vaginal bleeding has stopped. In case of persistent bleeding, even light, beyond the control visit, its disappearance should be checked within a few days. If an ongoing pregnancy is suspected, a further ultrasound scan may be required to evaluate its viability. http://www.usmedskart.com +1 (844) 257 2665

12. Contraindications for MTP Kit Any known allergy to any of the ingredients of MTP kit, any chance of ectopic pregnancy, IUD still in place, chronic adrenal failure, uterine bleeding disorders, woman on any anti-coagulant therapy, steroid dependent females, suffering from uncontrolled or severe asthma are the contraindications of MTP Kit. http://www.usmedskart.com +1 (844) 257 2665

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