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A highly active pancreatic cancer pipeline contains an array of products with varying molecule types and mechanisms of action, which provides a striking contrast to the current, chemotherapy dominated, market. Within the pipeline, there are 185 products that act on a first-in-class molecular target, representing 52% of the total pancreatic cancer pipeline products that have a disclosed molecular target
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Frontier Pharma Pancreatic Cancer - Aarkstore.com Category : Pharmaceuticals and Healthcare For More Information Visit : www.aarkstore.com
SummaryPancreatic cancer is the 12th most common cancer globally, and the fourth most fatal, with a mortality rate of 10.9 deaths per 100,000 people per year. The poor prognosis of pancreatic cancer patients has highlighted a significant need for new and improved approaches to treatment, which is not being met by the current market. A highly active pancreatic cancer pipeline contains an array of products with varying molecule types and mechanisms of action, which provides a striking contrast to the current, chemotherapy dominated, market. Within the pipeline, there are 185 products that act on a first-in-class molecular target, representing 52% of the total pancreatic cancer pipeline products that have a disclosed molecular target. A drastically different pipeline and market composition implies that the approach to pancreatic cancer treatment is changing and first-in-class innovation is playing a significant role in this. Scope- Gemcitabine based regimens continue to dominate the market, which has seen few new entrants over the past decade. The continued reliance on generic chemotherapies is one reason why the prognosis has shown little improvement. - What survival benefits do current therapies provide? - What are the current unmet needs that the pipeline needs to address? For More Information Visit : www.aarkstore.com
Table of Content 1 Table of Contents 2 1.1 List of Tables 3 1.2 List of Figures 3 2 Executive Summary 4 2.1 Large and Diverse Pipeline Contrasts the Limited Market 4 2.2 Pancreatic Cancer Shows High Levels of First-in-Class Innovation 4 2.3 High Deal Activity Reflects Dynamic Pipeline 4 3 The Case for Innovation 5 3.1 Growing Opportunities for Biologic Products 6 3.2 Diversification of Molecular Targets 6 3.3 Innovative First-in-Class Product Developments Remain Attractive 6 3.4 Regulatory and Reimbursement Policy Shifts Favor First-in-Class Product Innovation 7 3.5 Sustained Innovation 7 3.6 GBI Research Report Guidance 8 4 Clinical and Commercial Landscape 9 4.1 Disease Overview 9 4.2 Disease Symptoms 9 4.3 Epidemiology 9 For More Information Visit : www.aarkstore.com
List Of Tables Table 1: Tumor Node Metastasis Classification 13Table 2: Pancreatic Cancer Therapeutics, ECOG Performance Status Scores and Description 15Table 3: Pancreatic Cancer Therapeutics, Common Endpoints in Oncology Clinical Trials and their Description 16 Table 4: Pancreatic Cancer Therapeutics, Efficacy of GemcitabineMonotherapy 16 Table 5: Pancreatic Cancer Therapeutics, Efficacy of GemcitabineMonotherapy 17 Table 6: Pancreatic Cancer Therapeutics, Efficacy of Gemcitabine in Combination with Eloxatin20 List Of Figures Figure 1: Innovation Trends in Product Approvals 5 Figure 2: Sales Performance of First-in-Class and Non-First-in-Class Product Post Marketing Approval 7 Figure 3: Genetically Altered Signaling Pathways in Pancreatic Cancer 12 Figure 4: Overview of Marketed Products in Pancreatic Cancer 27 Figure 5: Overview of Pipeline Products 30 • Browse full report Or Sample Request @ • http://www.aarkstore.com/pharmaceuticals-healthcare/127902/frontier-pharma-pancreatic-cancer-identifying-and-commercializing-first-in-class-innovation
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