India’s 5 Most Influential Women Healthcare Leaders

1. www.womenworldindia.com www.womenworldindia.com W O R L D I N D I A VOL. 11 | ISSUE 03 | 2024 Models of Life Story of History and Evolution of Life Models  A Single Cell Magic How Do Cells in the Body Sense Seasonal Changes?  Dr Manbeena Chawla Executive Editor BioSpectrum Dr. Pioneering Communication in Life Sciences

4. Editor's Note Shapers of a Healthier and More Equitable Future I n this rapidly evolving landscape of healthcare, Indian women leaders are engraving milestones by introducing innovation, accessibilities, and change within the health arena. With barriers being cracked and, most importantly, leadership trends, they raise the stakes and, through results, become catalysts for enhanced healthcare services to millions around the globe. … This influence emanates from their ability to combine compassion with strategy, innovation with execution, and empathy with resilience. In a sector as critical and complex as healthcare, these women leaders are the epitome of visionary approaches that ensure both patient care and organizational growth are in the forefront. Their initiatives often go beyond clinical excellence to holistic healthcare, addressing systemic inefficiencies, and advocacy for inclusivity in services. Their leadership styles reflect a fine balancing of courage and adaptability. Creating intersectoral collaboration opportunities, investing in technological and infrastructural development, mentoring future professionals, and ensuring

5. universal access to quality care are steps taken by these women which transform the healthcare industry forever. They are what it feels like to lead with intent-ensuring access to proper care, building sustainable systems, and taking on all issues of healthcare inequity head-on. Equally notable is their focus on innovation. From championing digital health solutions to pioneering patient-centered care models, these leaders are at the forefront of leveraging technology to enhance healthcare delivery. Their work ensures that India not only meets its current healthcare challenges but also anticipates future needs with strategic foresight. The effect reaches well beyond the health systems themselves in fostering broader cultural change. In challenging stereotypes and being at the forefront of typically male leadership roles, these women role-model their positions and challenge others to similarly shape healthcare impact. Women World ‘India’s 5 Most Influential Women Healthcare Leaders’ are not only molding the future of medicine but are also remodeling societal norms. Their work confirms the need for different voices to drive change and ensure that healthcare in India remains compassionate, accessible, and forward- thinking. As we celebrate their success, we observe their indispensable role in shaping a healthier and more equitable future. Gaurav?PR?Wankhade

6. Dr Pioneering Communication in Life Sciences Cover Story 08

7. Content Profiles Dr Kavyachand Yalamudi Setting New Benchmarks in the Healthcare Industry with Khavyaa Hospitals- Khammam 20 28 A Goddess of Goodace Hospital – Soma Chakraborty Ensuring India Becomes World's Next Healthcare Hub Ar?cles 16 Models of Life Story of History and Evolution of Life Models 24 CXO 32 A Single Cell Magic How Do Cells in the Body Sense Seasonal Changes? Prioritizing Women's Wellness by Using Ayurvedic Wisdom

8. www.twitter.com/womenworldindia www.facebook.com/womenworldindia/ WE ARE ALSO AVAILABLE ON WE ARE ALSO AVAILABLE ON Pooja M. Bansal Editor-in-Chief CONTENT Managing Editor: Gaurav PR Wankhade Email sales@womenworldindia.com For Subscription www.womenworldindia.com Assisting Editor : Prajakta Zurale DESIGN Visualizer: Sandeep Tikode Art & Design Director : Rahul Shinde Art & Design Editor : Sarita Bhagat Asst. Designer : Nagaraj Patil , Satish Garde Copyright © 2024 WomenWorld India, All rights reserved. The content and images used in this magazine should not be reproduced or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from WomenWorld India. Reprint rights remain solely with WomenWorld India. SALES Vice President : Swapnali Vasaikar AVP : Tejaswini Whaval Asst. Manager : Nitin Patil Team Lead : Sapna Walunjkar Nov, 2024 Cover Price: Rs.300/- TECHNICAL Technical Head : Prachi Mokashi Technical Specialist: Rajeshwari Avhad Technical Consultant : Tanaji Fartade SME-SMO Research Analyst : Sagar Lahigade SEO Lead : Prashant Rathod

9. Featuring Organization Description Dr Anita Soni has more than 32 years of experience and is working as Full Time Consultant – Obstetrics & Gynaecology at Dr L H Hiranandani Hospital. Dr Anita Soni, Full Time Consultant– Obstetrics & Gynaecology Dr L H Hiranandani Hospital Dr Kavyachand Yalamudi, CEO and Managing Director Dr Kavyachand Yalamudi is the CEO and Managing Director of Khavyaa Hospitals in Khammam, Telangana and also a full-time visiting consultant physician. Khavyaa Hospitals- Khammam Dr Manbeena Chawla is the Executive Editor at BioSpectrum India and Asia. Dr Manbeena Chawla, Executive Editor BioSpectrum A passionate gynaecologist & laparoscopic surgeon, Dr Shweta Shah is the Founder and Director of TVAMEVA Clinic, at Andheri, Mumbai, with unparalleled experience of a decade in arena of woman health. Dr Shweta Shah, Gynaecologist and Laparoscopic Surgeon TVAMEVA Clinic After a successful career in Corporate Hospitals for ten years, Soma Chakraborty---Founder & Managing Director established Goodace hospital. Soma Chakraborty Goodace Hospital

10. Cover Story Dr Manbeena Chawla Executive Editor BioSpectrum

11. Dr Pioneering Communication in Life Sciences ““ While I was pursuing my PhD in the field of microbiology, I started working as an intern for a science magazine Connect at the Indian Institute of Science (IISc) in Bengaluru, where I developed a liking towards scientific communication, industry research, policy matters, etc.

12. India’s 5 Most Influential Women Healthcare Leaders “ I n a world where scientific advancements are rapidly reshaping our understanding of the universe, there is an urgent need for effective communication between scientists, industry and the consumers. One individual, deeply inspired by the power of science, felt a compelling urge to bridge this gap. BioSpectrum as a brand which is more than 20 years old; what has helped us sail through hard times is our commitment to deliver on time, team effort, and passion for writing and raising relevant developments within the life sciences sector for a better During her time as an intern at a science magazine in her PhD days, she witnessed firsthand the challenges scientists face in conveying their research to a broader audience. The importance of clear and engaging scientific communication became evident as she recognized the potential for science to positively impact society when its discoveries are effectively understood, appreciated and implemented. outome nationally.“ This experience ignited a passion for science communication and policy matters. She realized that by effectively communicating scientific findings, she could contribute to informed decision-making, foster public understanding of complex scientific issues, and inspire future generations of scientists. A PhD in microbiology with extensive research experience gathered at prestigious institutions such as the Indian Institute of Science (IISc) in Bengaluru, International Centre for Genetic Engineering and Biotechnology (ICGEB), and the National Institute of Immunology (NII) in Delhi, Dr Manbeena Chawla gradually understood that effective communication could significantly enhance the impact of scientific research. After completing her PhD degree, actively sought opportunities in the communication field and ultimately in 2017, joined BioSpectrum, a leading biotech business magazine. Since she dedicated herself to fostering collaboration and sharing insights among colleagues while learning from their wealth of experience. Through her journey, Dr Manbeena continues to inspire others in the industry, highlighting the crucial role of communication in advancing scientific knowledge and innovation. opportunities in the communication field and ultimately joined BioSpectrum, a well-established biotech business magazine brand, owned by MM Activ Sci-Tech Communications. The brand has operations in Delhi, Bengaluru, Mumbai, Pune, Nagpur and Singapore. More than 20 years old, BioSpectrum has been a significant part of Dr Manbeena's career for the past seven years. Throughout her tenure, she has witnessed both the highs and lows of the brand's journey. What has enabled the team to navigate challenging times is their unwavering commitment to deliver on time, collaborative efforts, and a shared passion for highlighting significant developments within the life sciences sector, ultimately aiming for improved outcomes on a national scale. Impact on Healthcare and Life Sciences Navigating the Science of Communication Dr Manbeena and her team maintain a robust network within the healthcare and life sciences sectors, actively engaging with key stakeholders, including government representatives, industry leaders, startups, and academics. They prioritize attending relevant meetings to connect with industry captains and gather insights to develop their articles, interviews, and analytical pieces. This engagement helps address bottlenecks and fosters innovation. While pursuing her PhD in microbiology at IISc in Bengaluru, Dr Manbeena began working as an intern at a science magazine called Connect, where she developed a strong interest in scientific communication, industry research, and policy matters. It was during this experience that she recognized the importance of discussing new discoveries in the scientific community, particularly in her home country, along with the challenges that accompany them. After completing her PhD, she actively sought

14. ““ We conduct regular training programmes and workshops for our team members while senior members organize specific induction programmes for new joiners.

16. Vision for BioSpectrum and the Biotechnology Industry Effective communication among team members has been crucial to Dr Manbeena’s success, and she credits her seniors and colleagues for the valuable lessons learned at every stage of her career. The rigorous training that PhD students undergo—focused on meeting deadlines, organizing events, and coordinating with peers—has equipped her with essential skills. She believes that a good leader is one who listens attentively, responds thoughtfully rather than reacting impulsively, and exercises patience when making important decisions. By delivering content promptly, Dr Manbeena’s team enhances customers' trust and confidence in their publication. Maintaining high-quality standards is essential, with each team member equally accountable for balancing reader’s expectations and business needs. This commitment leads to timely improvements in core processes, reducing inefficiencies and optimizing costs, ultimately boosting customer satisfaction and company profits. Vision for BioSpectrum: Strengthening Communication and Trust in Healthcare Under Dr Manbeena's leadership, BioSpectrum has been able to maintain its position as India’s premier publication covering the biotechnology business. It provides comprehensive analyses of policy issues, products, and services across various segments, including biopharma, bioinformatics, bioinfrastructure, and bioagriculture, making it the industry's most credible information source. Among the organization's most transformative initiatives are its networking events, which feature panel discussions on relevant and trending industry topics related to sectors such as biopharma, startups, and suppliers. Additionally, BioSpectrum has gained significant popularity through its annual award-based events, celebrating achievements in both the Indian and Asian life sciences sectors over the past few years. The COVID-19 pandemic posed significant challenges across various sectors, but the healthcare sector experienced an unprecedented surge in workload. Amidst widespread shutdowns, there was a pressing need for information and clarity. This urgency provided BioSpectrum with an opportunity to solidify its presence in the market. During this time, the team organized numerous webinars aimed at connecting with patients and the general public, who were often left in the dark about the evolving situation. Many were seeking reliable information regarding the disease, vaccine development, and the availability of diagnostic tests. Empowering Growth and Innovation In the realm of media and journalism, the team recognized their vital responsibility to disseminate accurate facts and figures. This commitment necessitated thorough and repetitive verification processes, a standard they vowed to uphold moving forward. continue to do so.““ BioSpectrum boasts a robust readership base for its websites, BioSpectrum India and BioSpectrum Asia. To cater to this audience, the team ensures that the websites are updated on an hourly basis, with the monthly digital magazine published on the first of each month. A variety of tools are utilized to enhance their digital marketing strategies. The organization prioritizes the development of its team members by conducting regular training programs and workshops. Senior members facilitate specific induction programs for new hires to help them acclimate. Additionally, BioSpectrum offers a hybrid work environment to enhance employee efficiency, fostering a balanced work culture. The organization also prides itself in maintaining an equal distribution of men and women within its workforce. Being in the field of media and journalism, we have a responsibility to put out correct facts and figures that require repetitive verifications – we will

18. Story of and of Models 16 | Nov, 2024 | www.womenworldindia.com

19. Models of Life 17 | Nov, 2024 | www.womenworldindia.com

20. T Darwin and the Evolutionary Model he journey of life on Earth is nothing short of awe- inspiring complexity, shaped by billions of years. This journey has been understood, represented, and sought across generations by scientists and thinkers in an attempt to explain life's origin, development, and the principles governing its existence: ‘models of life.’ These models not only reflect humanity's ever-expanding knowledge but, more importantly, show the continuous interplay of scientific discovery, philosophical inquiry, and technological advancement. The most impactful model of life in modern times was Charles Darwin's theory of evolution through natural selection, developed during the 19th century. In his landmark publication On the Origin of Species in 1859, Darwin introduced the idea that species share a common origin and change through time through the process of natural selection. This model of evolution revolutionized the concept of the diversity and interconnection of life by its dynamic, tree- like structure replacing a static, hierarchical view of life, based on change, adaptation, and survival, thus reshaping biology and influencing sociology, psychology, and anthropology. The Foundation: Ancient Philosophies and Early Theories The earliest models of life were deeply rooted in philosophy and mythology. Ancient Greek thinkers like Aristotle proposed the idea of a "Great Chain of Being," a hierarchical structure that placed all forms of life in a ranked order. This concept mirrored the societal structures of the time and emphasized the interconnectedness of life, albeit in a static and unchanging framework. The Molecular Era: DNA and the Code of Life The twentieth century brought a molecular era, marked by the discovery of DNA's structure by James Watson and Francis Crick in 1953, a breakthrough revealing the molecular basis of heredity and genetic variation, cementing DNA as the "blueprint of life." In contrast, cultures everywhere began to tell their own stories about life's differentness and complexity. From Hinduism's conception of an eternal cycle of birth and rebirth to indigenous cosmologies that placed humans in harmony with nature, these early models reflected humanity's intrinsic curiosity about life's purpose and origin. With the advent of molecular biology, life was transformed into a system based on information storage, retrieval, and expression. The scientists began to see life as an intricate interplay of genetic instructions and biochemical processes. The discovery of the double helix transformed medicine, agriculture, and biotechnology and let humans manipulate the very code of life. The Advent of Science: Mechanistic Models of Life It marked the changeover from speculative philosophical pursuits to empirical inquiry during the Renaissance. During the 16th and 17th centuries, there emerged the scientific revolution and paved the way for mechanistic models of life. In their works, living things appeared as highly complicated machines directed according to physical and chemical laws for René Descartes and many other thinkers. Systems Biology and Holistic Models Along with advancing scientific tools came the need to develop more integrative models of life. Systems biology is a discipline that emerged to view organisms as a network of interconnected systems rather than isolated parts. This holistic approach emphasizes the interactions between genes, proteins, cells, and their environments. The invention of the microscope in the 17th century unveiled a secret world, full of microorganisms in a world not previously so simple. A new chapter of questions about life's prime building blocks was ushered to the world by observations of such "animalcules," or microbes, that Antonie van Leeuwenhoek made in the form of future models in biology and chemistry. Incorporating complexity science, systems biology expanded our understanding of life's resilience and adaptability. It provided insights into how ecosystems function, how diseases like cancer arise from system-wide imbalances, and how organisms respond to environmental changes. 18 | Nov, 2024 | www.womenworldindia.com

21. Artificial Life and Computational Models The life models' story is yet to be told. It is a reflection of the insatiable thirst for knowledge, along with humanity's creativity and innovative impulse. As we move forward, these models will not only deepen our understanding of life but serve as guidance toward meeting the pertinent challenges of the future. The digital age has brought the most unprecedented advancements in computational models of life. Today, researchers simulate biological systems using algorithms, allowing them to create virtual ecosystems to study evolution, adaptation, and genetic drift. Artificial life is a field at the crossroads of biology and computer science, which explores principles of life through digital simulations, robotics, and synthetic biology. In essence, it is evolution in life models that symbolizes life itself: dynamic, adaptive, and continuously unfolding. Through these models, man continues to unravel the mysteries of existence, asking the question that has long puzzled generations: What is the meaning of being alive? These models challenge the traditional definitions of life, raising philosophical questions on the nature of existence. Can a self-replicating robot or a machine learning algorithm mimic life's fundamental traits? Such questions push the boundaries of our understanding and redefine what it means to be alive. Ethical and Philosophical Implications The evolution of life models is not only a scientific journey but also a very philosophical one. With each and every model, humanity's profound questions of what life really is, the ethical implications of changing it, and how much technological advancement should human beings be able to give rise to without destroying nature's complexity are forced to find answers. For example, tools such as CRISPR which can modify genes raise the question of unintended consequences, equitable access, and even the misuse of technology. Similarly, models of artificial life blur the distinction between what is natural and artificial and make us think through our relationship with technology. The Future of Life Models The coming years will see unparalleled changes in technology and in the environment, and such will change life models: Synthetic biology will make possible the designing of novel life forms; Artificial intelligence will introduce ever-deepening blurs about organic versus artificial systems at large. All these require models directed toward sustainability and ecological balance-the former by curbing climatic change and protecting biodiversity loss. 19 | Nov, 2024 | www.womenworldindia.com

22. Dr Kavyachand Yalamudi Setting New Benchmarks in the Healthcare Industry with Khavyaa Hospitals- Khammam T oday, in Women World India’s efforts to find ‘India’s 5 Most Influential Women Healthcare Leaders,’ we met Dr Kavyachand Yalamudi, Managing Director and CEO of Khavyaa Hospitals—Khammam. She regaled us with her enchanting story, which we are sharing here. Ma’am, as a visionary leader in the industry, could you take us back to the beginning of your journey? What motivated you to step into this dynamic ecosystem? My journey into the healthcare industry is one of resilience, learning, and a profound commitment to serving others. For me, it began with invaluable experiences as a consultant in various corporate hospitals. This phase of my career allowed me to immerse myself in the multifaceted operations of healthcare institutions, from patient care to administrative efficiency. I gained a first-hand understanding of the challenges and opportunities within the healthcare ecosystem, which became the guiding light for my entrepreneurial aspirations. These experiences were instrumental in shaping my vision for establishing a healthcare institution that prioritizes quality care and accessibility. Drawing upon the lessons learned during my consultancy tenure, I recognized the pressing need for enhanced healthcare services in underserved regions. This realization laid the foundation for starting Khavyaa Hospitals, with a mission to provide comprehensive healthcare to the population in and around Khammam and Bhadradri districts in Telangana, India. These areas, like many others, grapple with limited access to specialized medical services, and I felt a deep responsibility to address this gap. The establishment of Khavyaa Hospitals marked the beginning of a journey dedicated to delivering top-notch medical care to communities that needed it the most. However, such an ambitious endeavour could not have been accomplished without the unwavering support of my family. My parents, Mr Ravindar Yalamudi, Chairman of Khavyaa Hospitals, and Ms Parupalli Prasuna, Chief Operations Officer (COO), have been my constant pillars of strength. Their guidance and encouragement played a crucial role in helping me navigate the complexities of the healthcare sector. They believed in my vision and actively contributed their expertise to ensure that Khavyaa Hospitals not only met but exceeded the expectations of those it served. 20 | Nov, 2024 | www.womenworldindia.com

23. Their roles within the organization have been instrumental in driving its growth and success. My father’s strategic leadership as Chairman and my mother’s operational acumen as COO have laid the foundation for an institution that is both patient-centric and operationally efficient. Together, they instilled in me the values of compassion, dedication, and a commitment to excellence—principles that continue to guide our journey at Khavyaa Hospitals. diabetology services in the region, delivering unmatched outcomes in the treatment of diabetes and other related conditions. Our commitment to patient-centric care is evident in the remarkable strides we have made in improving the quality of life for diabetic patients. One of our standout achievements has been successfully transitioning numerous patients from insulin-dependent treatments to oral hypoglycemic drugs. This not only simplifies their treatment regimen but also alleviates the physical and psychological challenges often associated with insulin therapy. By reducing dependency on insulin, we empower our patients to lead healthier, more independent lives. This accomplishment is a testament to the expertise of our medical team and their innovative approaches to patient care. Your company has emerged as India's leading company in its niche. Could you share the guiding philosophy that has propelled your organization's success? Yes. Commitment, courage and consistency are my mantras for success. As stated earlier, my parents and my family have played a major role in the success of the firm. Beyond my parents, the encouragement and support of my extended family have also been pivotal. Their belief in my capabilities and their willingness to stand by me through the challenges of entrepreneurship have been invaluable. Building a healthcare institution is no small feat, but with the collective strength and support of my family, I was able to transform a vision into reality. The industrial landscape is continually evolving. Please brief our audience about your firm’s USPs and how you are currently positioned as one of the best companies in its sector. Khavyaa Hospitals, Khammam, stands as a trailblazer in healthcare delivery, redefining medical excellence in the Khammam and Bhadradri districts of Telangana. What sets us apart in this dynamic and competitive field are the distinctive features that have become the cornerstone of our reputation and success. Khavyaa Hospitals is proud to be the first hospital in the region to house an in-house endocrinologist, a dedicated lady physician, and cutting- edge Artificial Intelligence (AI)-enabled healthcare solutions. These unique selling propositions (USPs) underscore our commitment to innovation, inclusivity, and advanced patient care. Dr Kavyachand Yalamudi Managing Director and CEO Khavyaa Hospitals- Khammam A Revolutionary Presence in Endocrinology and Diabetology: At Khavyaa Hospitals, our endocrinology and diabetology departments are not just services; they are transformational avenues of care. As the pioneers in bringing endocrinology services to the region, we have bridged a critical gap in medical expertise. We take pride in being the go-to destination for managing complex hormonal and metabolic disorders. This is further reinforced by our position as the leading provider of endocrinology and 21 | Nov, 2024 | www.womenworldindia.com

24. India’s 5 Most Influential Women Healthcare Leaders The First Lady Physician: Empowering Care: Another distinguishing feature of Khavyaa Hospitals is the presence of the first dedicated lady physician in the region. This milestone highlights our emphasis on gender inclusivity and our dedication to addressing the unique healthcare needs of women. My being a female physician on board has been instrumental in creating a comfortable and safe environment for female patients, encouraging them to seek timely and necessary medical attention. My presence ensures that women in the region have access to specialized care, which is a critical step towards improving community health outcomes. Transforming Lives, One Patient at a Time: Our mission at Khavyaa Hospitals extends beyond providing treatment—it is about transforming lives. Our team of highly skilled medical professionals is dedicated to delivering outcomes that matter, ensuring that patients experience not just better health but also improved well- being. The success stories of diabetic patients who have transitioned to oral medications and the growing trust of the community in our capabilities are testaments to the impact we have made. Your visionary leadership style is often recognized as a driving force behind your company's achievements. Could you shed light on your approach to leadership and team building within the organization? AI-Powered Healthcare for Precision Medicine: Khavyaa Hospitals has embraced the power of Artificial Intelligence to revolutionize patient care and operational efficiency. As the first AI-equipped hospital in Khammam and Bhadradri districts, we leverage cutting-edge technologies to enhance diagnostic accuracy, streamline workflows, and provide personalized treatment plans. AI enables us to analyze complex medical data, predict patient outcomes, and optimize resource utilization, ensuring that we remain at the forefront of medical innovation. This forward-thinking approach ensures that our patients benefit from the latest advancements in medical science, positioning Khavyaa Hospitals as a pioneer in integrating technology with compassionate care. “ Khavyaa Hospitals Khammam is more than just a healthcare institution—it is a beacon of hope for the people of Khammam and Bhadradri districts. By combining advanced medical expertise, groundbreaking technology, and an unwavering commitment to patient welfare, we have redefined the standards of healthcare in the region. Our USPs reflect our drive to remain at the forefront of medical innovation and our dedication to delivering excellence in every aspect of care. My vision is to ensure that Khavyaa Hospitals - Khammam becomes synonymous with exceptional quality healthcare that is accessible to every patient in need. Backed by outstanding management, skilled healthcare providers, dedicated staff, and a dynamic team of marketing professionals, we have created a brand that stands apart. Our innovative marketing strategies have propelled Khavyaa Hospitals into the spotlight, establishing it as a trusted name across diverse regions in India and setting new benchmarks in the healthcare industry. Unparalleled Excellence in General Medicine:While endocrinology and diabetology are our flagship specialities, Khavyaa Hospitals is also renowned for its expertise in general medicine. Our holistic approach to healthcare ensures that patients receive comprehensive and coordinated care for a wide spectrum of health conditions. Our focus on preventive healthcare, early diagnosis, and effective treatment plans sets us apart as a trusted partner in the community's health journey. The essence of the industry lies in innovation, disruptions, and enhancing the end-user experience. How does your company strike a balance between operational efficiency and customer satisfaction? Our vision for the future is to make Khavyaa Hospitals Khammam a beacon of accessible and exceptional healthcare across Telangana, ensuring our services reach every corner of the state. We take pride in achieving a remarkable 95% patient retention rate, a testament to our unwavering commitment to exceptional care. Through consistent follow-ups and timely medication management, we ensure our patients' health remains a top priority. Notably, we have transformed the lives of numerous diabetic patients by transitioning them from insulin dependency to oral hypoglycemic therapies, significantly enhancing their quality of life. 22 | Nov, 2024 | www.womenworldindia.com

25. responsibilities, we not only enhance their skills but also pave the way for their professional growth. Additionally, we take pride in creating numerous job opportunities and fostering a culture of empowerment and development within our organization. As a leader in India's industrial sector, your company has likely faced its share of challenges. Could you share an instance where your team's resilience and ingenuity triumphed over adversity? As a women-led organization, we have encountered numerous challenges along our journey. However, these obstacles have only fueled our determination, driving us to innovate and introduce groundbreaking advancements in the diagnostics and treatment of various diseases. Through resilience and a commitment to excellence, we have emerged stronger and more impactful over time. The COVID-19 pandemic has reshaped industries globally. How has your company made contingency plans for similar uncertain events in the future? We are fully equipped with advanced technology, skilled staff, and robust resources to combat any pandemic effectively. In our commitment to delivering timely and quality care, we are actively planning collaborations to introduce comprehensive insurance policies, ensuring seamless access to treatment for COVID-19 patients and those affected by other medical conditions. Digitalization and technological advancements are crucial aspects of the modern industrial ecosystem. How does your company integrate these principles into its core functioning and contribute to a technovative future? Khavyaa Hospitals Khammam proudly stands as a pioneer in integrating Artificial Intelligence into Endocrinology and Diabetology, setting a benchmark in advanced healthcare. By seamlessly synchronizing our Electronic Health Records and laboratory diagnostics with AI technology, we have revolutionized early diagnosis and the prediction of complications associated with diabetes, thyroid disorders, hormonal imbalances, and other endocrine issues. This innovative approach enables us to deliver precise, proactive care, transforming patient outcomes. Looking ahead, what is your vision for your company? How do you aspire to continue making a significant impact on India's industrial landscape? Our vision for the future is to make Khavyaa Hospitals Khammam a beacon of accessible and exceptional healthcare across Telangana, ensuring our services reach every corner of the state. We aim to extend our impact nationwide through teleconsultation, providing seamless medical expertise to patients in other parts of India. Additionally, we are planning to expand our footprint by establishing branches in other states, bringing world-class healthcare closer to those in need. The workforce is the cornerstone of any successful organization. How does your company foster a culture of growth, skill development, and empowerment among its employees? For further assistance, please email us at chandk2010@gmail.com or call us at +919704617383. At Khavyaa Hospitals Khammam, we are committed to nurturing talent and empowering individuals through comprehensive training programs for our staff, nursing students, and DMLT students. By offering diverse roles and 23 | Nov, 2024 | www.womenworldindia.com

26. O winter. While these changes do affect our overall health and mood as well as even immune functions, how cells in the body can sense and respond to them is a very intriguing scientific research. Cells are far more intricate than what one would imagine. ur bodies are indeed equipped with super mechanisms to adjust to changes, from the long daylight hours of summer to the chilly nights of Within these basic units, there exist various internal systems interacting with the surroundings to indicate changes in season that would eventually affect the process within the body. It turns out there's "magic" in this single-cell treatment as evidence of how our bodies have evolved to somehow synchronize with Earth's cycles. Suprachiasmatic Nucleus (SCN): The Brain's Clock For example, circadian rhythms as controlled by the brain is a simple way in which our body responds to changes in seasons. The SCN (suprachiasmatic nucleus), which is in the hypothalamus, is known as the master clock, where it controls rhythms in accordance with light and dark stimuli. When we are awake, exposure to light triggers the SCN to send signals through the pineal gland that suppresses melatonin, the chemical causing sleep. Conversely, when the days are short and daylight hours are decreased, it provides less stimulation for SCN to produce lesser amounts of melatonin, which affects more than sleep patterns, to prepare the body for the colder months ahead. How Do Cells Sense Seasonal Changes? in the Body The SCN is therefore the central coordinating hub of peripheral clocks which are present in virtually all cell types. These clocks modulate various metabolic and cellular processes so that even though individual cells cannot visually perceive changes due to seasonal events they still believe in signals orchestrated by the SCN that would keep them in tune with these changes. Photoperiodism: How Light Influences Cells Seasonal changes are also felt by cells via photoperiodism-the biological reaction to changes in the duration of light throughout the seasons. This phenomenon is not limited to mankind but rather involves countless other animals and plants. Photoreceptors in the retina can be specialized and measure changes in daylight hours, passing this information along to the SCN, which-as described above-regulates the body's general response. Therefore, for instance, shorter days will cause the biological processes responsible for metabolism, hormone production, and immune response to be activated in order to get the body ready for the seasonal changes. 24 | Nov, 2024 | www.womenworldindia.com

27. A Single Cell Magic 25 | Nov, 2024 | www.womenworldindia.com

28. Cells of the body, in most tissues but more specially in skin, respond to light exposure by creating vitamin D. Lowered sunlight in winter means vitamin D production is decreased and cellular functions are affected as the body relates less efficiently with the absorption of calcium or the immune response. Similarly, brain cells respond to shorter days with increased melatonin production, affecting sleep patterns and mood among many other things. Thus, the body can change with seasons without use of technology. generally peak with the colder months when infections such as colds and flu are more readily available. Immune cells can sense seasonal changes through a few key avenues: Temperature and Daylight Exposure: The immune cells react to the reduced temperatures as well as the shorter daylight exposures by modulating the production of inflammatory molecules in the body to prepare to fight the infections. Hormonal Responses and Their Cellular Consequence Vitamin D Receptors: Many immune cells are vitamin D receptors. Hence, with less sunlight exposure in winter, the vitamin D decreases, which affects the immune system. Fewer levels of vitamin D may make the immune cells more vulnerable to infections, thus partially explaining why most occur in winter. Hormones are the messengers in the body whose job is to deliver seasonal messages to cells in most types of systems. The effects of daylight duration not only impact melatonin, cortisol, and serotonin-but these hormone changes affect the way cells respond to seasonal environmental changes. Melatonin: The creasing fall of night means the hormone levels of melatonin rise up, accelerating the fall into sleep by dusk since there is less sunlight. Melatonin attaches to specific receptors on the cells of the body and initiates an uninterrupted wave of messages to the cells that it is time to get restful, repair themselves, and boost up their immune systems during colder climates. These adaptations better enable our bodies to fight seasonal infections and respond to the demands placed on the immune system throughout the year. Gene Expression and Epigenetics: A Cellular Memory of Seasons Seasonal changes even affect gene expression inside the cells, it has been found that there are some genes which the cells are active at specific times of the year. For example, those genes that are part of inflammation processes are more active during the winter months, thus giving immunity a head start by having higher rates of seasonal illnesses. These cells thus have an "epigenetic" memory of the environment allowing them to prepare and adapt to seasonal patterns without any annual stimulation. Cortisol: Cortisol is a hormone produced by the adrenal glands; levels will vary with seasonal changes. Increased cortisol during winter due to reduced daylight also interacts with other receptors on cells in various organs to impact immune responses, metabolism, and even emotions. Serotonin: Commonly referred to as the "happiness hormone," serotonin is positively correlated with sunlight exposure and strongly influences mood levels. The reduced exposure of sunlight in winters reduces serotonin production, hence generally influencing mood. Cells may even alter what they do in response to signals from their neighboring cells and tissues, adjusting gene expression to adapt to the seasonal needs of the organism. This is particularly relevant to cells making up organs or systems directly impacted by seasonal variations, like cells in the skin, immune cells, and even neurons in the brain. These hormones maintain cellular processes through sticking to receptors on the cell membranes, enabling the cell to "feel" changes and respond accordingly. The fluctuations of these hormones in the two seasons is important because it makes sure that cells within a biological system remain well-balanced and ready for sudden changes in their surroundings. Seasonal Fluctuations on Immune Cells It is very sensitive to seasonal changes, and the majority of immune cells have their activities at various levels throughout the year. For instance, immunological activities 26 | Nov, 2024 | www.womenworldindia.com

29. Subscribe Today Stay in the known. Subscribe to WOMENWORLDINDIA Get WOMENWORLDINDIA Magazine in print and digital on www.womenworldindia.com W O R L D I N D I A

30. A Goddess of Goodace Hospital Ensuring India Becomes World's Next Healthcare Hub Soma Chakraborty Founder and Managing Director Goodace Hospital 28 | Nov, 2024 | www.womenworldindia.com

31. India’s 5 Most Influential Women Healthcare Leaders I n the dynamic landscape of leadership, women who embody the essential traits of empowering leaders are making significant strides in India’s business arena. Among these influential figures is Soma Chakraborty, the Founder and Managing Director of who stands out as a prominent leader in this field. Recognized as one of the most influential women leaders in healthcare, Soma has dedicated her career to transforming the healthcare sector, leaving a lasting impact on India’s socio-economic landscape. establishment stemmed from a burning desire to carve out her path in life. Even when confronted with adversity, Soma demonstrated remarkable resilience and determination. Overcoming Obstacles with Optimism Goodace Hospital , Soma's path has not been devoid of challenges. A life- altering car accident left her daughter with severe injuries that required constant care. For a year, Soma stayed by her daughter’s side in the hospital, grappling with emotional turmoil and uncertainty about the future. During this tumultuous time, she lost her job and depleted her savings, facing financial hardship and mental distress. “ Visionary Leadership and Social Commitment Soma’s career spans decades, during which she has made substantial contributions across various sectors. Her visionary leadership is characterized by an unwavering commitment to social causes and a relentless advocacy for gender equality. As a trailblazer in healthcare, she has shattered glass ceilings and defied stereotypes, paving the way for countless women to pursue their aspirations and reach their full potential. Her influence extends beyond healthcare into philanthropy, education, and social activism, where she empowers women to break barriers and challenge societal norms. In less than three years since its inception, Goodace Hospital has evolved into a 54-bed facility equipped with state-of-the-art infrastructure including fully equipped ICUs and specialized surgical units. When recognized for her achievements as an influential healthcare leader, Soma humbly remarked, “I would like to confess that a huge step is pending to become an influential healthcare leader in the world. I have achieved very little. Though I always celebrate this small achievement, which motivates me to go ahead for the next goal.” This statement reflects her humility and continuous drive for growth. Despite these setbacks, Soma refused to succumb to despair. She remained hopeful and determined to rebuild her life. When an opportunity arose in a different sector, she embraced it wholeheartedly as the Head of Marketing at a renowned hospital. This marked a turning point in her career; from then on, she channelled her energy into achieving new goals. The Power and Courage of a Woman on Mission Soma's journey exemplifies the importance of daring to dream and the determination required to turn those dreams into reality. From a young age, she aspired to build a successful career fueled by dedication and passion. Her refusal to be confined by limitations or traditional views on retirement speaks volumes about her relentless pursuit of excellence and her desire to make a meaningful impact through her work. Taking New Flights Soma's story of resurgence embodies resilience and unwavering commitment to her dreams. After 12 successful years in corporate hospitals, she felt compelled to create an institution that could make a tangible difference in people’s lives. Motivated by a vision of establishing a hospital catering to middle-class families with affordable healthcare options, she embarked on this challenging journey. She believes that success is not merely a product of luck but rather the result of hard work, perseverance, and a steadfast commitment to one’s goals. Throughout her career, Soma has faced numerous challenges but remained resolute in her pursuit of her dreams. Her aspiration to create her 29 | Nov, 2024 | www.womenworldindia.com

32. The COVID-19 pandemic highlighted the urgent need for accessible healthcare amid rising casualties due to insufficient hospital beds and financial barriers. This urgency reinforced Soma's resolve to realize her dream. Undeterred by the daunting task ahead, she meticulously researched and leveraged her 18 years of experience in the medical field to lay the groundwork for Goodace Hospital. Recognizing the substantial investment required for such an endeavour, Soma courageously committed her savings to fund it while utilizing her extensive network built over the years in the industry. Commitment to Accessible Healthcare Soma’s dedication to ensuring healthcare access for all is evident through her tireless efforts in establishing Goodace Hospital. In May 2021, amidst the ongoing pandemic, she opened its doors, initially serving COVID-19 patients in dire need of care. Despite numerous challenges during this period, Soma's passion for providing healthcare never wavered. Through community service initiatives, Soma has earned recognition that extends beyond local boundaries; Goodace Hospital has become a beacon of hope, offering major surgeries at minimal costs. The hospital’s empanelment with various health schemes ensures that diverse patients can benefit from its services. During the pandemic, Goodace Hospital played an essential role in caring for over 200 COVID-19 patients while performing more than 3,000 surgeries—including complex procedures like brain tumour surgeries—showcasing its expertise in handling diverse medical cases. As the hospital grew, she welcomed two partners who shared her vision for expanding access to quality healthcare services. However, balancing professional responsibilities with personal sacrifices proved difficult; she spent nearly 9- 10 months away from her daughter while managing hospital operations just a kilometre away from where her daughter was cared for. Running a hospital during such crises demanded unwavering dedication and sacrifice. Soma recalls countless sleepless nights spent ensuring smooth operations while delivering life-saving services around the clock. Her commitment underscores her resolve to guarantee healthcare access for all despite obstacles. Beyond medical treatment, Goodace Hospital invests heavily in community outreach through free OPD services provided by super-specialist doctors for underserved populations and health check-up camps in rural districts, reflecting Soma’s belief in proactive healthcare initiatives. Developing an Integrated Healthcare Delivery Model Soma's vision for creating a holistic healthcare ecosystem has materialized through relentless dedication and pursuit of excellence. In less than three years since its inception, Goodace Hospital has evolved into a 54-bed facility equipped with state-of-the-art infrastructure, including fully equipped ICUs and specialized surgical units. This comprehensive setup allows the hospital to provide critical care and specialized surgeries while ensuring high-quality patient care. A Visionary Leader Soma envisions establishing five or six hospitals across different states where middle-class families can access quality treatment from super-specialist doctors. She emphasizes that effective leadership requires grounding oneself in core values: “It serves as your moral compass for leading and inspiring your team.” 30 | Nov, 2024 | www.womenworldindia.com

33. She advocates adapting services through innovation while identifying gaps that may arise during uncertain times—a philosophy rooted deeply in operational excellence principles aimed at enhancing patient experiences alongside cost-efficiency measures via digital transformation initiatives within Goodace Hospital operations. Her management philosophy evolved into seven principles focused on building trust, integrity, empathy, accountability, and respect for individuals’ dignity while fostering skill development among team members. Soma asserts that “your team is the root of your success” and emphasizes selecting capable leaders within teams who can foster relationships built on trust rather than fear or authority—highlighting how ego can hinder organizational growth. Future Aspirations Looking ahead towards future endeavors, Soma expresses aspirations to create Medical Hubs across states comprising nursing colleges alongside pharmaceutical industries, demonstrating ambition aligned closely with India’s growing healthcare market demands amid population needs. Commitment to Social Justice At the heart of Soma's leadership lies a deep commitment to social justice and equality. She champions causes such as women's empowerment and education for underprivileged children while leveraging resources towards meaningful change through philanthropic endeavours that uplift individuals out of poverty by providing education and skills training opportunities. Her leadership exemplifies transformative power driven by empathy coupled with perseverance—a legacy that inspires countless aspiring entrepreneurs seeking success, regardless of their backgrounds or circumstances, on their journeys toward realizing dreams. In essence, Soma Chakraborty continues inspiring others through unwavering dedication towards empowering communities while fostering social impact—a testament showcasing how visionary leadership can create lasting change within society at large—ensuring every individual receives quality healthcare irrespective of financial constraints faced throughout their lives. Navigating Challenges with Innovation In today’s healthcare landscape marked by evolving patient expectations post-pandemic—where patients are more vocal about their needs—Soma believes proactive communication is key: “Don’t wait for patients; inform them about changes affecting service delivery.” 31 | Nov, 2024 | www.womenworldindia.com

34. Priori?zing Women's Wellness by Using Ayurvedic Wisdom I Lanka to India in less than an hour, but talking to our neighbours take us months. Through all the conveniences, time still feels like Sand, getting away with each time we try to hold it. We want to achieve everything. In times when women were not given the right to educate, they had no choice but to be at home catering to only homely things. Then came a time when education was prioritized thanks to our women leaders and women started building up better generations. They evolved into financially stable beings but still had to juggle between home and work and this became too much! It came to a point of explosion as women then started suffering with glucose imbalance issues, PCOD, infertility, painful periods, weight issues, anxieties and depressions. The struggle is real adding hormonal changes into this chaotic pattern or less sleep, more stress and imbalanced diet. n today’s fast paced world of immense Internet Connectivity, the world we live in, seems to have shrunken into our fists, or fingertips! We reach from Sri That is the time when women started looking back to their roots, which were written in an authentic evident-based medically researched books of Ayurveda. Ayurveda originates from India, a land where every State has a geographical and morphological variation. India is seen as the country of colours and you can see this great variation even in the fruits and vegetables that grow specific to the States. 32 | Nov, 2024 | www.womenworldindia.com

35. 33 | Nov, 2024 | www.womenworldindia.com

36. We often forget to understand that we work the best when we relax. Unlike our primitive selves where humans needed to learn to work harder, and walk faster; now times have changed and we now need apps to teach us to relax and take life slower, going one step at a time, like the walk uphill towards a Monastery. It will also give brain power and refresh your taste buds. If you eat this laddoo at breakfast, it will give you more energy for the day. If you eat this by evening, it will make you feel lazy. Prioritizing WHEN to eat certain things than WHAT to eat, is more important. 3 Golden Rules of Thumb for Maintaining Gut and Brain health: With so much happening on the outside, women need to pause, and look inwards to find their centre of balance deep within them. We have heard of ‘Me Time’ which is usually taken as 1-2 hrs of time one needs to take away form their day to do something that they enjoy doing. Those hours are fully their own and they must focus on themselves doing whatever they like- be it watching Netflix, sleeping, scrolling, reading, going for a walk, etc. 1. Curb your sweet tooth a minute before meals. This will give you satisfaction, and turn the food into energy without causing heaviness. 2. Fill out your journal of gratitude by thanking your heart first thing in the morning (as it worked the whole night for you) and brain last thing at night (as it was burning for you the whole day). A new concept of ‘Mindful Me Time’ refreshingly lets a woman focus on every task she does by pausing to take a minute to herself. In that minute she can turn inwards. She can access her emotions. If there are negativities built up, these 60 secs provide her time to regulate and check in with herself by doing what she likes the most. She could grab a green tea, stretch, nap or go for a brisk walk down the corridor for the next few mins. This ‘mindful me-time’ is not an hour post work, but a minute away re-centring in every new task. 3. Go for a walk or do any one of your favorite physical activity for atleast 20 mins in a day, but out in open. Breathe and get your happy hormones going. I am born in a family of very strong women. My grandmother at the age of 85 still makes incredible artificial flowers and that’s her hobby which she is occupied in, happily for almost 12 hours a day. She is the one who says- Women need to have hobbies that keep them happy throughout their lives. Once career, families and everything else passes, you are left on your own. So know your thing which is purely and solely yours and can make you happy. Prioritizing that, I have seen my mother though being a practising doctor, touches base with her jewellery making skills very often. I dance. I dance to any tune I love and that liberates me. Posing a question to you, what is that one thing as a women would you keep doing that exuberates happiness from you? A woman’s happiness is her basic life- need, not a luxury. And it starts when you prioritize your own health beyond anything. If she keeps well, the entire family flourishes. Stress levels and Hormonal responses: Knowing your own mind-body constituency, known as individualistic ‘Prakruti’ is a good place to start knowing your own body. You can then self-access stress levels and your own hormonal responses. Hormones talk, only if we listen to them. These are not just mood swings, but an intense internal chemical reaction that go inside our body throughout the month. Our responses to stress are often dependent on how we are feeling internally. To feel internally good tools such as Meditation, Yogasanas, Ayurvedic Seasonal Therapies and a balanced approach towards diet and lifestyle are essential. I saw my mother doing Yogasanas for maintaining her flexibility while her kids were growing up. Though I didn’t take it seriously back then, I realized that we often take the preventive aspects for granted in our lives. This then piles up into a disorder one-day digging holes into our pockets. Dr. Devika Deshmukh MD Ayurveda Panchakarma (Gold Medallist India) RMAS, CMT (USA) Ayurveda has a very individualistic approach to understanding the physical, physiological and psychological aspects of a human being. For eg: eating a laddoo, might give you mental happiness and glucose in the blood. 34 | Nov, 2024 | www.womenworldindia.com

40. www.womenworldindia.com W O R L D I N D I A