Lab-Scale Extruder & Spheronizer Combo_ Revolutionizing Granulation Technology

1. Lab-Scale Extruder & Spheronizer Combo: Revolutionizing Granulation Technology Introduction Granulation plays a pivotal role in the formulation research and product development of pharmaceuticals, chemicals, and food industries. The process ensures uniformity in size, shape, and density, contributing to improved product performance and stability. In response to the growing demand for efficient and scalable granulation solutions, VJ Instruments introduces the Lab-Scale Extruder & Spheronizer Combo. This integrated system combines cutting-edge extrusion and spheronization technologies to facilitate precise granule and pellet formation, optimizing formulation development with unmatched efficiency and versatility. The Extruder Component: Versatile and Efficient The Extruder is a fundamental part of the system, designed for low-pressure granulation techniques that preserve the integrity of sensitive formulations. Unlike traditional granulation methods, which may compromise product quality, this extruder employs a controlled process to generate uniform extrudates suitable for further refinement. Key Features of the Extruder 1. Interchangeable Heads for Flexibility ○ The system includes four interchangeable extrusion heads, allowing researchers to customize the extrusion process based on specific formulation requirements. This adaptability ensures that a broad spectrum of materials can be processed with ease. 2. Bench-Top Scalability ○ Designed for laboratory-scale research, the extruder can handle batches as small as 200 grams, making it an ideal choice for initial formulation trials. This reduces material wastage and allows for cost-effective experimentation before scaling up. 3. Low-Pressure Granulation ○ The system operates at a low-pressure threshold, minimizing heat generation and preserving the physicochemical properties of sensitive ingredients. This is particularly advantageous for pharmaceutical applications where active ingredients require careful handling. 4. Indicative Results for Scale-Up

2. ○ The extruder provides results that are indicative of larger-scale production, enabling a seamless transition from laboratory research to commercial manufacturing. The Spheronizer Component: Precision in Pellet Formation Following extrusion, the Spheronizer component transforms cylindrical extrudates into uniform, spherical pellets with enhanced flowability and compressibility. This step is crucial in industries where pellet uniformity directly impacts product performance. Key Features of the Spheronizer 1. Large Friction Plate for High-Quality Spheres ○ Equipped with a 230 mm diameter friction plate, the spheronizer ensures consistent shaping of extrudates into spheres. The precision-engineered design optimizes the transformation process, delivering high-quality pellets suitable for various applications. 2. Wide Range of Pellet Sizes ○ The system can produce spheres ranging from 0.5 mm to 10.0 mm in diameter, catering to diverse industry requirements. Whether for pharmaceutical controlled-release formulations or uniform granules in the food industry, this feature offers significant versatility. 3. User-Friendly Design ○ The spheronizer features a GMP-compliant design, ensuring hygiene and regulatory compliance in pharmaceutical and food production environments. ○ Easy disassembly allows for quick cleaning and maintenance, minimizing downtime between batches. ○ Variable plate speeds offer precise control over spheronization conditions, enabling researchers to fine-tune parameters for optimal results. 4. Stainless Steel Control Panel ○ The integrated stainless steel control panel enhances durability and provides intuitive operation. Users can adjust parameters seamlessly, ensuring consistency across multiple trials. Advantages of the Lab-Scale Extruder & Spheronizer Combo 1. Seamless Integration for Enhanced Productivity The Lab-Scale Extruder & Spheronizer Combo eliminates the inefficiencies associated with using separate systems. By seamlessly transitioning from extrusion to spheronization, researchers can streamline their workflow, reducing material loss and processing time. 2. Cost-Effective Research and Development

3. With the ability to process small batches, the system significantly reduces the cost of formulation trials. Researchers can experiment with different compositions without excessive material expenditure, leading to faster and more economical product development. 3. Improved Product Uniformity The precision-engineered components ensure uniform granule and pellet formation, enhancing the quality and consistency of final products. This is especially critical in pharmaceuticals, where uniformity influences drug release profiles and bioavailability. 4. Adaptability Across Industries From pharmaceuticals to food processing and chemical manufacturing, the system's versatility makes it a valuable tool across multiple industries. Whether for sustained-release medications, food flavor encapsulation, or chemical catalysts, the Extruder & Spheronizer Combo delivers superior results. 5. GMP Compliance and Easy Maintenance Designed in accordance with Good Manufacturing Practices (GMP), the system ensures compliance with industry standards. Additionally, its easy-to-clean design minimizes contamination risks, supporting high-quality production. Applications Across Industries 1. Pharmaceutical Industry ● Controlled-Release Drug Formulations: Enables the creation of uniform drug pellets for modified-release applications. ● Taste-Masked Granules: Ideal for developing taste-masked formulations, improving patient compliance. ● Multi-Particulate Drug Delivery Systems: Supports innovative drug delivery solutions for enhanced therapeutic effects. 2. Food Industry ● Encapsulation of Flavors and Nutrients: Preserves active ingredients, extending shelf life. ● Uniform Granule Formation: Ensures consistency in powdered and granular food products. ● Instant Beverage Mixes: Produces free-flowing granules that dissolve efficiently. 3. Chemical Industry ● Catalyst Manufacturing: Facilitates the creation of uniform catalyst beads for chemical reactions.

4. ● Agricultural Formulations: Enhances the delivery of pesticides and fertilizers in controlled-release formats. ● Industrial Additives: Produces high-quality granules for various industrial applications. Conclusion The VJ Instruments Lab-Scale Extruder & Spheronizer Combo represents a transformative advancement in granulation technology. By integrating cutting-edge extrusion and spheronization capabilities into a single system, it empowers researchers and product developers to create high-quality formulations with precision and efficiency. Its versatile design, cost-effective operation, and user-friendly features make it an invaluable asset across multiple industries. Whether for pharmaceutical formulations, food technology, or chemical manufacturing, this dynamic duo offers unparalleled control, consistency, and scalability, making it an essential tool for modern R&D laboratories. Embrace the future of granulation technology with VJ Instruments and take your product development to the next level.