1 / 23

P. Finocchiaro INFN Laboratori Nazionali del Sud, Catania, Italy

Photosensor applications. Medical imaging: scintillation detectors for TOF-PET. P. Finocchiaro INFN Laboratori Nazionali del Sud, Catania, Italy. Medical Imaging: X-rays. radiography. Computed Tomography. analog picture is impressed on the film.

aamaral
Download Presentation

P. Finocchiaro INFN Laboratori Nazionali del Sud, Catania, Italy

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Photosensor applications Medical imaging: scintillation detectors for TOF-PET P. Finocchiaro INFN Laboratori Nazionali del Sud, Catania, Italy

  2. Medical Imaging: X-rays radiography Computed Tomography analog picture is impressed on the film digital data acquired, slices are computed (and printed on the film)

  3. Medical Imaging: Magnetic Resonance MRI sensitive to the magnetic moment of protons digital data acquired slices of H distribution are computed

  4. Medical Imaging: g-rays SPECT digital data acquired, slices are computed and printed on the film g-camera a g radioactive tracer is injected collimator photodetector g collimator scintillator

  5. Medical Imaging: g-rays PET residual nucleus b+decay e+ 511 keV 511 keV a b+ radioactive tracer is injected

  6. Medical Imaging: g-rays PET digital data acquired • data selected by: • 2-pixel coincidence • energy ≈ 511 keV data stored as sinograms or list mode Energy [a.u.] Energy [a.u.] • sinogram: a special 2D histogram • list mode: data recorded event by event slices are computed can be combined with CT or MRI

  7. Medical Imaging: g-rays PET data stored as sinograms data stored in list mode slices are computed can be combined with CT or MRI • sinogram: a special 2D histogram • list mode: data recorded event by event

  8. Medical Imaging: summary

  9. Medical Imaging: g-rays TOF-PET ∆t ∆x ∆t Line Of Response (LOR) -6 0 3 -3 6 X position along LOR

  10. Medical Imaging: g-rays TOF-PET digital data acquired data stored as list mode: position, energy, time • data selected by: • 2-pixel coincidence • energy ≈ 511 keV slices are computed with probability weight can be combined with CT or MRI improved resolution reduced background

  11. Medical Imaging: g-rays TOF-PET further issue: Depth Of Interaction DOI Unknown DOI Known DOI several methods available to handle DOI blurred images

  12. Medical Imaging: g-rays TOF-PET the TOPEM project TOPEM: A TOF-PET endorectal probe for diagnosis and follow up of the prostate cancer size ≈ 25 x 15 x 50 mm3 outer PET detector Lines of coincidence backplane contacts endorectal PET probe probe should also be compatible with MRI array of SiPM ≈ 450 LYSO scintillators connector array of SiPM backplane contacts

  13. Medical Imaging: g-rays TOF-PET the TOPEM project outer PET detector SiPM 3x3x15 mm3 LYSO scintillator SiPM endorectal PET probe single scintillator prototype need to measure position (LOR, time), energy, DOI

  14. Medical Imaging: g-rays TOF-PET the TOPEM project need to measure position (LOR, time), energy, DOI LOR known from geometry detector i detector j time measured by the two scintillators position along LOR X position along LOR

  15. Medical Imaging: g-rays TOF-PET the TOPEM project need to measure position (LOR, time), energy, DOI

  16. Light propagation and attenuation attenuation length latt • latt is a constant depending on • material type • shape • surface finish • wrapping

  17. Medical Imaging: g-rays TOF-PET the TOPEM project need to measure position (LOR, time), energy, DOI detector i detector j energy measured by the two scintillators 511 keV 511 keV measured energy independent of the hit position • scintillator surface and wrapping chosen to obtain a convenient latt ≈ 15 mm

  18. Medical Imaging: g-rays TOF-PET the TOPEM project need to measure position (LOR, time), energy, DOI

  19. Medical Imaging: g-rays TOF-PET the TOPEM project need to measure position (LOR, time), energy, DOI

  20. Medical Imaging: g-rays TOF-PET the TOPEM project need to measure position (LOR, time), energy, DOI DOI measured by the two SiPM DOI

  21. Medical Imaging: g-rays TOF-PET the TOPEM project need to measure position (LOR, time), energy, DOI DOI calibration

  22. Conclusion need to use detectors with: good time resolution (≈ 200 ps) reasonable energy resolution (< 15% @ 511 keV) reasonable DOI resolution: double readout surface finish & wrapping such that latt ≈ L

  23. Thanks for your patience...

More Related